Andrea Alimonti: Catalogue data in Autumn Semester 2020

Name Prof. Dr. Andrea Alimonti
FieldExperimental Oncology and Translational Cancer Medicine
Institute of Oncology Research
Via F. Chiesa 5
6500 Bellinzona
Telephone+4158 6667115
DepartmentHealth Sciences and Technology
RelationshipFull Professor

376-0303-00LColloquium in Translational Science (Autumn Semester)1 credit1KM. Ristow, A. Alimonti, N. Cesarovic, C. Ewald, V. Falk, J. Goldhahn, K. Maniura, J. Mitchell, R. M. Rossi, S. Schürle-Finke, G. Shivashankar, E. Vayena, V. Vogel
AbstractCurrent topics in translational medicine presented by speakers from academia and industry.
ObjectiveGetting insight into actual areas and problems of translational medicine.
ContentTimely and concise presentations of postgraduate students, post-docs, senior scientists, professors, as well as external guests from both academics and industry will present topics of their interest related to translational medicine.
Prerequisites / NoticeNo compulsory prerequisites, but student should have basic knowledge about biomedical research.
377-0517-00LOncology Restricted registration - show details
Only for Human Medicine BSc
2 credits2VA. Alimonti, A. Calcinotto, A. Stathis, J.‑P. Theurillat
AbstractAdvances in our knowledge of cancer genetics and the immune system are changing the ways in which we treat various types of cancer. This is a unique course designed to help students to learn about cutting-edge principle of cancer genetics, targeted and immunotherapies from leading expert in the field.
ObjectiveStudents will learn basic concepts of cancer patient’s management and anti-cancer therapy both clinically approved and experimental.
ContentBasic knowledge in oncology
- The cancer outbreak and its prevention
- Tumor diagnostic, imaging and screening
- Basic principle of cancer managment (neo-adjuvant, adjuvant, palliative. RT/Surgery/CT)
- Management of tumor recurrence and Follow up

- The promise of Immuno-oncology
- Basic Tumor Immunology
- Checkpoint Blockade
- CAR T and other experimental Immunotherapies

Oncology practice
- Clinical application: Evidence Based Medicine in oncology
- Clinical application: Immunology
- Clinical application: Chemo-radiotherapy and Theragnostic
- Clinical application: Targeted therapy in cancer

Experimental oncology
- Co-clinical trial: the relevance of mouse models
- Next Generation sequencing and precision oncology
- Microbiota and Cancer therapy
- Liquid biopsy (CTC and clusters), proteomics, circulating DNA/RNA hip or hope?).

Targeted therapy
- From Arsenic Trioxide and Glivec to modern targeted therapies
- Cancer Genomics and Epigenomics
- Basic knowledge of signal transduction and cancer metabolism
- Mechanism of resistance to targeted therapies

Experimental oncology 2
- Senescence therapy and senolytic
- Cancer metabolism (therapy and imaging)
- Nanomedicine and cancer (approved and experimental)
- How to do Oncology in the Big Pharma
Prerequisites / NoticeVoraussetzungen:
LE 377-0105-00L Bewegungsapparat
LE 377-0107-00L Nervensystem
LE 377-0201-00L Herz-Kreislauf-System
LE 377-0203-00L Atmungs-System
LE 377-0205-00L Nieren und Homöostase
LE 377-0301-01L Blut, Immunsystem
LE 377-0301-02L Ernährung und Verdauung
LE 377-0301-03L Endokrinologie, Stoffwechsel
LE 377-0401-00L Sinnesorgane
LE 377-0403-00L Haut und Anhangsorgane