Enrico Klotzsch: Catalogue data in Spring Semester 2020 |
| Name | Dr. Enrico Klotzsch |
| Address | Professur Angew. Mechanobiologie ETH Zürich, GLC G 12.1 Gloriastrasse 37/ 39 8092 Zürich SWITZERLAND |
| enrico.klotzsch@hest.ethz.ch | |
| URL | http://n.ethz.ch/~kenrico |
| Department | Health Sciences and Technology |
| Relationship | Lecturer |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 376-1611-00L | Biomedical Interfaces  | 4 credits | 2V + 1U | S. Lickert, V. Vogel, M. Aramesh, E. Klotzsch | |
| Abstract | This class serves as an introduction into the design of materials for biomedical applications. Its focus lies on controlling interactions at the interface between biomolecules or living cells and synthetic materials. Knowing some basic concepts allows us to define prototypical requirements for material surfaces and to utilize molecular engineering principles for their realization. | ||||
| Learning objective | 1. The students will know basic rules that determine the interaction of biological molecules or cells with synthetic materials on the nanoscale. 2. The students will be able to define essential requirements how to functionalize materials in the context of specific biomedical applications. 3. The students will be able to predict the outcome of self-assembly processes and utilize these to achieve a desired function or biological behavior at interfaces. | ||||
| Content | - protein-surface interactions - anti-adhesive surface coatings - biosensors - bacteria-surface interactions - cell-nanoparticle interactions - drug delivery systems - cell-matrix interactions - soft tissue engineering | ||||
| Lecture notes | Handouts of the lecture can be accessed online. All hand-outs are in English. | ||||
| Literature | Selected chapters of - Biomaterials Science: an Introduction to Materials in Medicine, by B. Ratner, 3rd Ed. Academic Press (2013). - Biomimetic Materials and Design: Biointerfacial Strategies, Tissue Engineering and Targeted Drug Delivery, by A.K. Dillow and A.M. Lowman, CRC Press (2002). - Biomaterials: Principles and Practices, by J.Y. Wong et al., CRC Press (2013). - Molecular Biology of the Cell, by B. Alberts et al., Taylor & Francis, 5th Ed. (2007). Detailed literature references will be provided in the lectures. | ||||
| Prerequisites / Notice | This interdisciplinary class addresses students from all disciplines at the Bachelor level. Profound basic knowledge in cell biology and biochemistry is required. A few lectures will be held in english. | ||||