Elisabeth Giger: Catalogue data in Autumn Semester 2022 |
| Name | Dr. Elisabeth Giger |
| Address | Kinderspital Zürich Steinwiesstrasse 75 8032 Zürich SWITZERLAND |
| Telephone | 0442663865 |
| gigere@ethz.ch | |
| URL | http://n.ethz.ch/~gigere |
| Department | Chemistry and Applied Biosciences |
| Relationship | Lecturer |
| Number | Title | ECTS | Hours | Lecturers | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 535-0421-00L | Galenical Pharmacy I  | 2 credits | 2G | J.‑C. Leroux, E. Giger | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Principles and technologies for the manufacturing of dosage forms and drug delivery systems. Knowledge of pharm. excipients, materials, containers, liquid and semi-solid dosage forms, their production, function, quality and application. Comprehension of molecular interactions in solution and colloidal systems. Comprehension of interfacial phenomena and stabilization measures in dosage forms. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | Knowledge of the most important pharmaceutical excipients, materials, containers, liquid and semi-solid dosage forms, of their production, function, quality, stability and application. Comprehension of the molecular interactions in solution and colloidal systems. Comprehension of interfacial phenomena and stabilization measures in disperse dosage forms. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Introduction and overview of important fundamentals, principles and technologies for the development and manufacturing of dosage forms and drug delivery systems. Overview of the most important pharmaceutical excipients and polymers, their structure, properties and processing; importance of materials properties for containers. Pharmaceutical solvents, fundamentals of solubility and solubilization of drugs. Water treatment processes, sterilization techniques and quality requirements of pharmaceutical water. Parenteral dosage forms and liquid ophthalmics. Surfactants, micelle formation and colloidal systems. Liquid suspensions and emulsions. Stabilization measures in dosage forms. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | L.V. Allen Jr, T. B. McPherson, Ansel's Pharmaceutical Dosage Forms and Drug Delivery Systems, 12th Ed, Wolters Kluwer, Philadelphia 2023. M. E. Aulton and K. M. G. Taylor, Aulton's Pharmaceutics: The design and manufacture of medicines, 6th ed, Elsevier, Edinburgh, 2022. L. Felton, Remington - Essentials of Pharmaceutics, Pharmaceutical Press, London, 2013. Sinko P.J., Martin's Physical Pharmacy and Pharmaceutical Sciences, 7th ed, Wolters Kluwer, Philadelphia, 2017. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Language: German and English | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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