G.V. Shivashankar: Katalogdaten im Herbstsemester 2022
|Herr Prof. Dr. G.V. Shivashankar
Paul Scherrer Institute
5232 Villigen PSI
|Gesundheitswissenschaften und Technologie
|Colloquium in Translational Science (Autumn Semester)
|N. Cesarovic, A. Alimonti, C. Ewald, V. Falk, J. Goldhahn, K. Maniura, M. Ristow, R. M. Rossi, S. Schürle-Finke, G. Shivashankar, E. Vayena, V. Vogel
|Current topics in translational medicine presented by speakers from academia and industry.
|Getting insight into actual areas and problems of translational medicine.
|Timely and concise presentations of postgraduate students, post-docs, senior scientists, professors, as well as external guests from both academics and industry will present topics of their interest related to translational medicine.
|Voraussetzungen / Besonderes
|No compulsory prerequisites, but student should have basic knowledge about biomedical research.
|Cells undergo major functional alterations as we age. In this course, we will discuss the basic molecular and cell biological mechanisms of cellular ageing. We will also discuss diseases related to cellular ageing and current rejuvenation and therapeutic strategies for cellular ageing in health and disease.
|- Basic molecular and cell biological mechanisms of cellular ageing;
- Diseases related to cellular ageing;
- current rejuvenation and therapeutic strategies for cellular ageing in health and disease.
|Lecture-1: Hallmarks of cellular ageing
Lecture-2: Cellular microenvironment & extra-cellular matrix
Lecture-3: Cell morphometric changes & cytoskeletal remodeling
Lecture-5: Mitochondrial dysfunction
Lecture-6: Endo-membrane signaling
Lecture-7: Nuclear signaling & epigenetic alternations
Lecture-8: Chromatin remodeling & gene expression
Lecture-9: Genomic integrity
Lecture-10: Ageing cell secretome and cellular homeostasis
Lecture-11: Diseases associated with cellular ageing
Lecture-12: Cellular rejuvenation strategies
Lecture-13: Therapeutic interventions to cellular ageing
Lecture-14: Concluding lecture