Klaus Eyer: Catalogue data in Autumn Semester 2022 |
Name | Dr. Klaus Eyer |
Department | Chemistry and Applied Biosciences |
Relationship | Assistant Professor |
Number | Title | ECTS | Hours | Lecturers | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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529-0043-01L | Analytical Strategy | 6 credits | 3G | R. Zenobi, K. Eyer, S. Giannoukos, D. Günther | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | Problem-oriented development of analytical strategies and solutions. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | Ability to create solutions for particular analytical problems. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | Individual development of strategies for the optimal application of chemical, biochemical, and physico-chemical methods in analytical chemistry solving predefined problems. Experts from industry and administration present particular problems in their field of activity. Principles of sampling. Design and application of microanalytical systems. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | Copies of problem sets and solutions will be distributed free fo charge | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Prerequisites / Notice | Prerequisites: 529-0051-00 "Analytical Chemistry I (3. Semester)" 529-0058-00 "Analytical Chemistry II (4. Semester)" (or equivalent) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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535-0011-00L | Drug Seminar The course is reserved for students registered in the Master's programme in Pharmacy or in Pharmaceutical Sciences | 5 credits | 9S | J. Hall, A. Burden, K. Eyer, C. Halin Winter, S.‑D. Krämer, J.‑C. Leroux, C. Müller, V. I. Otto, U. Quitterer, J. Scheuermann, R. Schibli, K. Silina, C. Steuer | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | The course provides a platform for the investigation, presentation and discussion of a topic with relevance to the field of pharmaceutical sciences. Students work in small groups on a chosen topic, they write a mini-review and present their work on a one day symposium. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | The main objectives of this course are: - students develop their scientific reflection (Critical Thinking) and working skills by working independently on a relevant pharmaceutical topic - students gain in-depth knowledge of the topic investigated - students train their scientific writing and presentation skills - students train their ability to plan a project and work in a team | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | The Course Drug Seminar takes place during the first 7 weeks of the 1. Master semester. It is a compulsory course of the MSc Pharmacy curriculum and an elective course in the MSc PharmSciences. The course provides a platform for the investigation, presentation and discussion of a topic with relevance to the field of pharmaceutical sciences. During the course, students work in small teams on a topic of their choice and elaborate a written mini-review and an oral presentation. Each team is tutored by a lecturer of the Institute of Pharmaceutical Sciences. The work is mainly based on literature search / review, but may also involve conducting interviews or site visits, if appropriate. The final presentations of all groups will take place in the framework of a dedicated Symposium held in the middle of the semester. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Prerequisites / Notice | Only for students of MSc Pharmacy and MSc Pharmaceutical Sciences. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
535-0810-00L | Gene Technology | 2 credits | 2G | K. Eyer, J. Scheuermann | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | The course gives a description and summary of the field of gene technology and its pharmaceutical applications. The course focuses on important methods and technologies and their application for genomic, transcriptomic and proteomic analyses in human biology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | The course gives an overview of current state-of-the art and advancement in the fields of gene technology. Herein, the course focuses on genomic, transcriptomic and proteomic analysis and their uses in drug discovery and biomedical applications. The course is structured into lectures and practical examples drawn from the research field. Upon completion, the students are familiar and know current state-of-the art of methods and applications, but are also able to classify, contrast and apply different strategies and methods within the field of gene technology. The course is suited for advanced undergraduate and early graduate students in pharmaceutical sciences or related fields. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | I) Genomics and transcriptomics Methods and Techniques: • Recombinant DNA technology • Next generation sequencing methods, sequencing of genomes • CRISPR technology Application to human biology: • Functional genomics/transcriptomics • Principles of cancer, genetic diseases • Therapies: cell-based therapies/gene therapies/DNA and RNA vaccination II) Proteomics Methods and Techniques: • Protein cloning and expression • The antibody molecule • Measurement and determination of biomolecular interactions • Protein characterization and engineering • Modifications and radioactive labelling Application to human biology: • Protein therapeutics • Proteomic approaches for identification of novel disease-related targets and biomarkers III) Drug discovery: Protein-based libraries •Immune repertoire mining •Display and selection technologies 1. antibody phage display 2. other polypeptide display technologies 3. small-molecules display: DNA-encoded chemical libraries | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Lecture notes | The lecture series follows the above-described content, and the students are provided with the lecture slides and additional notes. The additional notes are needed for the in-depth study of the individual topics, and to set the frame and content of the in-class group work of the chosen examples. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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535-0900-00L | Seminars on Drug Discovery and Development | 1 credit | 1K | R. Schibli, K. Eyer, C. Halin Winter, J. Hall, J.‑C. Leroux, U. Quitterer, G. Schneider, H. U. Zeilhofer | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Abstract | State-of-the-art information on drug discovery and development by experts from academia and industry. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Learning objective | State-of-the-art information on drug discovery and development. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Content | Seminar series of the Institute of Pharmaceutical Sciences. Experts from academia and industry report on relevant topics. |