Christian Rellstab: Katalogdaten im Herbstsemester 2023 |
| Name | Herr Dr. Christian Rellstab |
| Adresse | WSL Zürcherstrasse 111 MG C39 8903 Birmensdorf ZH SWITZERLAND |
| Telefon | 0447392542 |
| christian.rellstab@usys.ethz.ch | |
| Departement | Umweltsystemwissenschaften |
| Beziehung | Dozent |
| Nummer | Titel | ECTS | Umfang | Dozierende | |||||||||||||||||||||||||||||
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| 701-1676-01L | Genomics of Environmental Adaptation  Prerequisites: good knowledge in population genetics and some experience in using GIS and R is required. | 2 KP | 3G | R. Holderegger, F. Gugerli, C. Rellstab | |||||||||||||||||||||||||||||
| Kurzbeschreibung | This five-day winter school aims at teaching advanced Master students, PhD students and postdoctoral researchers on aspects of the genomics of environmental adaptation. It provides both theoretical background and hands-on exercises on major topics of contemporary environmental genomics such as signatures of selection, outlier analysis, genotype-environment associations, or GWAS. | ||||||||||||||||||||||||||||||||
| Lernziel | The genomics of environmental adaptation is an evolving scientific field of both basic and applied interest. Researchers make increasing use of diverse methodological approaches built on concepts from ecology, evolutionary biology and population genomics. This five-day winter school introduces students to some major concepts and methods of environmental genomics, i.e., (i) how the environment and adaptive genetic variation are related and (ii) how signatures of genomic adaptation can be detected in natural populations. The winter school focuses on current methods and hands-on exercises, emphasizing an understanding of the underlying concepts and a discussion of benefits, limitations and pitfalls of environmental genomics. It is specifically aimed at the needs of advanced Master students, PhD students and early postdoctoral researchers. | ||||||||||||||||||||||||||||||||
| Inhalt | Topics: (1) Molecular markers and next generation sequencing techniques; neutral and adaptive genetic variation, genetic drift and genetic population structure. (2) Outlier analysis: concept, methodology and types of outlier analyses. (3) Environmental data: which environmental data are available and used to identify signatures of adaptation; data limitations; collinearity. (4) Genotype-environment associations (landscape genomics): concept and types of genotype-environment associations; false discovery rates; genomic offset. (5) Genotypes and phenotypes: GWAS; follow-up analyses. | ||||||||||||||||||||||||||||||||
| Skript | Hand-outs will be distributed. | ||||||||||||||||||||||||||||||||
| Literatur | The course requires 4 hours of preparatory reading of selected papers on the genomics of environmental adaptation. The papers will be distributed by e-mail. | ||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | Grading will be according to a written report (8-10 pages), in which students will have to design a complete study in environmental genomics, and according to student contributions during the course. Prerequisites: students must have good knowledge in population genetics and evolutionary biology and some experience with R and GIS. | ||||||||||||||||||||||||||||||||
Kompetenzen |
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