Kirsten Bomblies: Katalogdaten im Frühjahrssemester 2022

Auszeichnung: Die Goldene Eule
NameFrau Prof. Dr. Kirsten Bomblies
Professur Pflanzenevolutionsgen.
ETH Zürich, LFW E 56.1
Universitätstrasse 2
8092 Zürich
Telefon+41 44 632 71 89
BeziehungOrdentliche Professorin

551-0002-00LAllgemeine Biologie II Belegung eingeschränkt - Details anzeigen 4 KP4GU. Sauer, K. Bomblies, O. Y. Martin
KurzbeschreibungGrundlagen der
Biochemie (Makromoleküle, Membranen, Zellstrukturen, Stoffwechsel)
Molekulargenetik (Genexpression und Regulation, vom Gen zum Protein)
Physiologie höherer Pflanzen (Struktur, Wachstum, Entwicklung, Nährstoffe, Transport und Reproduktion)
LernzielVerständnis grundlegender Konzepte molekularer Biologie und Physiologie.
InhaltZellluläre Funktionen auf der Ebenen von Molekülen und Strukturen.
Molekulare Vorgänge in der Prozessierung vom Gen zum Protein.

Die folgenden Campbell Kapitel werden behandelt:

Woche 1-5:
5 Biological macromolecules and lipids
7 Cell structure and function
8 Cell membranes
10 Respiration: introduction to metabolism
10 Cell respiration
11 Photosynthetic processes

Woche 6-9:
16 Nucleic acids and inheritance
17 Expression of genes
18 Control of gene expression
19 DNA Technology

Woche 9-13:
35 Plant Structure and Growth
36 Transport in vascular plants
37 Plant nutrition
38 Reproduction of flowering plants
39 Plants signal and behavior
SkriptKein Skript
LiteraturCampbell, Reece et al: "Biologie" (11th global edition); Pearson 2018.
551-0003-AALGeneral Biology I+II
Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben.

Alle andere Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen.
7 KP13RU. Sauer, K. Bomblies, O. Y. Martin, A. Widmer
KurzbeschreibungGeneral Biology I: Organismic biology to teach the basic principles of classical and molecular genetics, evolutionary biology and phylogeny.

General Biology II: Molecular biology approach to teach the basic principles of biochemistry, cell biology, cgenetics, evolutionary biology and form and function of vacular plants.
LernzielGeneral Biology I: The understanding of basic principles of biology (inheritance, evolution and phylogeny) and an overview of the diversity of life.

General Biology II: The understanding basic concepts of biology: the hierarchy of the structural levels of biological organisation, with particular emphasis on the cell and its molecular functions, the fundamentals of metabolism and molecular genetics, as well as form and function of vascular plants.
InhaltGeneral Biology I:
General Biology I focuses on the organismal biology aspects of genetics, evolution and diversity of life in the Campbell chapters 12-34.

Week 1-7 by Alex Widmer, Chapters 12-25
12 Cell biology Mitosis
13 Genetics Sexual life cycles and meiosis
14 Genetics Mendelian genetics
15 Genetics Linkage and chromosomes
20 Genetics Evolution of genomes
21 Evolution How evolution works
22 Evolution Phylogentic reconstructions
23 Evolution Microevolution
24 Evolution Species and speciation
25 Evolution Macroevolution

Week 8-14 by Oliver Martin, Chapters 26-34
26 Diversity of Life Introdution to viruses
27 Diversity of Life Prokaryotes
28 Diversity of Life Origin & evolution of eukaryotes
29 Diversity of Life Nonvascular&seedless vascular plants
30 Diversity of Life Seed plants
31 Diversity of Life Introduction to fungi
32 Diversity of Life Overview of animal diversity
33 Diversity of Life Introduction to invertebrates
34 Diversity of Life Origin & evolution of vertebrates

General Biology II: The structure and function of biomacromolecules; basics of metabolism; tour of the cell; membrane structure and function; basic energetics of cellular processes; respiration, photosynthesis; cell cycle, from gene to protein; structure and growth of vascular plants, resource acquisition and transport, soil and plant nutrition.

Specifically the following Campbell chapters will be covered:
3 Biochemistry Chemistry of water
4 Biochemistry Carbon: the basis of molecular diversity
5 Biochemistry Biological macromolecules and lipids
7 Cell biology Cell structure and function
8 Cell biology Cell membranes
10 Cell biology Respiration: introduction to metabolism
10 Cell biology Cell respiration
11 Cell biology Photosynthetic processes
16 Genetics Nucleic acids and inheritance
17 Genetics Expression of genes
18 Genetics Control of gene expression
19 Genetics DNA Technology
35 Plant structure&function Plant Structure and Growth
36 Plant structure&function Transport in vascular plants
37 Plant structure&function Plant nutrition
38 Plant structure&function Reproduction of flowering plants
39 Plant structure&function Plants signal and behavior
SkriptNo script
LiteraturCampbell et al. (2018) Biology - A Global Approach. 11th Edition (Global Edition)
Voraussetzungen / BesonderesBasic general and organic chemistry

This is a virtual self-study lecture for non-German speakers of the "Allgemeine Biology I (551-0001-00L) and "Allgemeine Biology II (551-0002-00L) lectures. The exam will be written jointly with the participants of this lecture.
551-0120-01LPlant Biology Colloquium (Spring Semester)
This compulsory course is required only once. It may be taken in autumn as course 551-0120-00 "Plant Biology Colloquium (Autumn Semester)" or in spring as course 551-0120-01 "Plant Biology Colloquium (Spring Semester)".
2 KP1KC. Sánchez-Rodríguez, K. Bomblies, W. Gruissem, O. Voinnet, S. C. Zeeman
KurzbeschreibungCurrent topics in Molecular Plant Biology presented by internal and external speakers from accademia.
LernzielGetting insight into actual areas and challenges of Molecular Plant Biology.
551-1294-00LGenetics, Genomics5 KP4GJ. Corn, K. Bomblies, U. K. Genick, Z. Kontarakis, R. Schlapbach, G. Schwank, S. Sunagawa, O. Voinnet, K. Weis
KurzbeschreibungGenetics and epigenetics form the blueprints for all life. Understanding genetics is critical to understanding everything from evolution to cancer. This course covers the fundamentals of modern genetics, with an emphasis on molecular mechanisms, and the use of genetic tools to understand biological biological processes in bacteria, model organisms and humans.
LernzielAt the end of this course you will know how traits are inherited between generations and how they move through populations. You will understand the molecular processes that give rise to observable genetic outcomes. You will know the most important genetic tools in different organisms. You will understand how genetic “problems” give rise to a variety of diseases and the fundamentals of modern genetic engineering.
InhaltThe appearance and function of an organism (phenotype) is determined by the interplay between its genome (genotype) and the environment: Genotype + environment = phenotype. Understanding these interactions to the point where we can ultimately predict the phenotype from knowledge of the genotype and environmental factors is one of the great challenges of biology.

The goal of this course is that you learn how genetic information is passed between individuals and through populations, and how genetic/genomic methods are used to understand biological processes (the connection between genotype and phenotype).

This course is organized into two parts.

The first part is a solid grounding in modern genetic theory, with an emphasis on molecular mechanisms. What do we really mean when we say traits are passed between generations? How do we measure traits? How do we turn the observable frequency of trait occurrence into an understanding of a gene in a chromosome? Why is sex such a big deal and why do organisms put so much energy into it? How do organisms protect their genomes and what goes wrong when that protection fails?

The second part is a series of expert lectures on applications in modern genetics. How can one use solid understanding of genetic theory to learn about other aspects of biology? How does next-generation sequencing work? What is CRISPR genome editing? Why is brewer’s yeast a powerful genetic tool? How does documenting disease occurrence in many, many individuals tell you where the responsible gene lies on a chromosome? How can one screen all the genes in a genome to figure out which one(s) are responsible for a phenotype?
SkriptThe learning material and slides of the input lectures are available on Moodle. There you will also find further information (articles, links, videos).
LiteraturThe course will mostly following Genetics: from Genes to Genomes (7th edition) by Goldberg, Fischer, Hood, and Hartwell.
Voraussetzungen / BesonderesThe course builds on the course Bio IA, in particular on that course's content regarding genetics and genomics. The course is based on frontal lectures on genetic theory, expert lectures by genetics practitioners from D-BIOL, self-learning units on Moodle, and exercises.
551-1520-00LEvolutionary Genetics to Explore the Role of Genes in Trait Evolution Belegung eingeschränkt - Details anzeigen
Number of participants limited to 8.

The enrolment is done by the D-BIOL study administration.
6 KP7PK. Bomblies, M. Dukic, J. Westermann
KurzbeschreibungGuided research projects to study gene evolution in plants, coupled with functional investigation in the lab. We focus in particular on candidate genes for phenotypes diverged between plant populations adapted to different habitats.
LernzielTo learn both bioinformatic and laboratory skills relevant to plant molecular genetics. Students will lern to analyse gene sequence evolution from existing sequence data, and will learn laboratory follow-up to investigate the potential role of alternate alleles of candidate genes in generating phenotypes.
InhaltGuided research projects to study the biochemical consequences of adaptive evolution in a variety of proteins. Mostly the focus is on proteins that seem to have evolved to help stabilize meiosis to temperature and/or polyploidy in plants.
SkriptWill be provided, as appropriate, during the course.
LiteraturWill be provided, as appropriate, during the course.