Esther Wehrle: Katalogdaten im Frühjahrssemester 2021

NameFrau Dr. Esther Wehrle
Adresse
Institut für Biomechanik
ETH Zürich, GLC H 21.1
Gloriastrasse 37/ 39
8092 Zürich
SWITZERLAND
Telefon+41 44 633 79 52
E-Mailesther.wehrle@hest.ethz.ch
DepartementGesundheitswissenschaften und Technologie
BeziehungDozentin

NummerTitelECTSUmfangDozierende
376-1721-00LBone Biology and Consequences for Human Health2 KP2VG. A. Kuhn, J. Goldhahn, E. Wehrle
KurzbeschreibungBone is a complex tissue that continuously adapts to mechanical and metabolic demands. Failure of this remodeling results in reduced mechanic stability ot the skeleton. This course will provide the basic knowledge to understand the biology and pathophysiology of bone necessary for engineering of bone tissue and design of implants.
LernzielAfter completing this course, students will be able to understand:
a) the biological and mechanical aspects of normal bone remodeling
b) pathological changes and their consequences for the musculoskeletal system
c) the consequences for implant design, tissue engineering and treatment interventions.
InhaltBone adapts continuously to mechanical and metabolic demands by complex remodeling processes. This course will deal with biological processes in bone tissue from cell to tissue level. This lecture will cover mechanisms of bone building (anabolic side), bone resorption (catabolic side), their coupling, and regulation mechanisms. It will also cover pathological changes and typical diseases like osteoporosis. Consequences for musculoskeletal health and their clinical relevance will be discussed. Requirements for tissue engineering as well as implant modification will be presented. Actual examples from research and development will be utilized for illustration.