Berend Snijder: Catalogue data in Autumn Semester 2022

Name Prof. Dr. Berend Snijder
FieldMolecular Systems Biology
Address
Inst. f. Molekulare Systembiologie
ETH Zürich, HPM H 44
Otto-Stern-Weg 3
8093 Zürich
SWITZERLAND
Telephone+41 44 633 71 49
E-mailsnijder@imsb.biol.ethz.ch
URLhttp://www.snijderlab.org
DepartmentBiology
RelationshipAssistant Professor

NumberTitleECTSHoursLecturers
551-1303-00LCellular Biochemistry of Health and Disease Information Restricted registration - show details
Number of participants limited to 20.
4 credits2SV. Korkhov, T. Ishikawa, M. Jagannathan, R. Kroschewski, G. Neurohr, M. Peter, A. E. Smith, B. Snijder, K. Weis
AbstractDuring this Masters level seminar style course, students will explore current research topics in cellular biochemistry focused on the structure, function and regulation of selected cell components, and the consequences of dysregulation for pathologies.
ObjectiveStudents will work with experts toward a critical analysis of cutting-edge research in the domain of cellular biochemistry, with emphasis on normal cellular processes and the consequences of their dysregulation. At the end of the course, students will be able to introduce, present, evaluate, critically discuss and write about recent scientific articles in the research area of cellular biochemistry.
ContentGuided by an expert in the field, students will engage in classical round-table style discussions of current literature with occasional frontal presentations. Students will alternate as discussion leaders throughout the semester, with the student leader responsible to briefly summarize key general knowledge and context of the assigned primary research paper. Together with the faculty expert, all students will participate in discussion of the primary paper, including the foundation of the biological question, specific questions addressed, key methods, key results, remaining gaps and research implications.
LiteratureThe literature will be provided during the course
Prerequisites / NoticeThe course will be taught in English.
551-1415-00LImage-Based Drug Screening in Human Blood for Personalized Medicine Restricted registration - show details
Number of participants limited to 5.
The enrolment is done by the D-BIOL study administration.
6 credits7PB. Snijder, further lecturers
AbstractImage based screening allows to measure in high throughput the phenotype of millions of individual cells to external perturbations. We have recently shown that image-based screening in human blood can help to find active treatments for patients with blood cancers. In this course we will take the students through the entire workflow (to the extent that biosafety regulations allow it).
ObjectiveTake the students through the entire workflow from experimental design, to screen, to imaging and analysis.
-Learn to design an image-based screening experiment
-Observe human blood sample handling
-Perform immunofluorescence & automated confocal microscopy
-Image analysis and result interpretation
-Result presentation
Literature-Relevant study: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(17)30208-9/fulltext
-Editorial commentary: https://www.thelancet.com/journals/lanhae/article/PIIS2352-3026(17)30213-2/fulltext