Berend Snijder: Katalogdaten im Herbstsemester 2022

NameHerr Prof. Dr. Berend Snijder
LehrgebietMolekulare Systembiologie
Inst. f. Molekulare Systembiologie
ETH Zürich, HPM H 44
Otto-Stern-Weg 3
8093 Zürich
Telefon+41 44 633 71 49

551-1303-00LCellular Biochemistry of Health and Disease Information Belegung eingeschränkt - Details anzeigen
Number of participants limited to 20.
4 KP2SV. Korkhov, T. Ishikawa, M. Jagannathan, R. Kroschewski, G. Neurohr, M. Peter, A. E. Smith, B. Snijder, K. Weis
KurzbeschreibungDuring this Masters level seminar style course, students will explore current research topics in cellular biochemistry focused on the structure, function and regulation of selected cell components, and the consequences of dysregulation for pathologies.
LernzielStudents will work with experts toward a critical analysis of cutting-edge research in the domain of cellular biochemistry, with emphasis on normal cellular processes and the consequences of their dysregulation. At the end of the course, students will be able to introduce, present, evaluate, critically discuss and write about recent scientific articles in the research area of cellular biochemistry.
InhaltGuided by an expert in the field, students will engage in classical round-table style discussions of current literature with occasional frontal presentations. Students will alternate as discussion leaders throughout the semester, with the student leader responsible to briefly summarize key general knowledge and context of the assigned primary research paper. Together with the faculty expert, all students will participate in discussion of the primary paper, including the foundation of the biological question, specific questions addressed, key methods, key results, remaining gaps and research implications.
LiteraturThe literature will be provided during the course
Voraussetzungen / BesonderesThe course will be taught in English.
551-1415-00LImage-Based Drug Screening in Human Blood for Personalized Medicine Belegung eingeschränkt - Details anzeigen
Number of participants limited to 5.
The enrolment is done by the D-BIOL study administration.
6 KP7PB. Snijder, weitere Dozierende
KurzbeschreibungImage based screening allows to measure in high throughput the phenotype of millions of individual cells to external perturbations. We have recently shown that image-based screening in human blood can help to find active treatments for patients with blood cancers. In this course we will take the students through the entire workflow (to the extent that biosafety regulations allow it).
LernzielTake the students through the entire workflow from experimental design, to screen, to imaging and analysis.
-Learn to design an image-based screening experiment
-Observe human blood sample handling
-Perform immunofluorescence & automated confocal microscopy
-Image analysis and result interpretation
-Result presentation
Literatur-Relevant study:
-Editorial commentary: