Michael Nash: Catalogue data in Autumn Semester 2021

Name Prof. Dr. Michael Nash
FieldEngineering of Synthetic Systems
Address
Engineering v. Synthetischen Syst.
ETH Zürich, BSS H 41
Klingelbergstrasse 48
4056 Basel
SWITZERLAND
E-mailmichael.nash@bsse.ethz.ch
DepartmentBiosystems Science and Engineering
RelationshipAssociate Professor

NumberTitleECTSHoursLecturers
636-0102-00LAdvanced Bioengineering
Only for Biotechnologie Master, Programme Regulations 2017.
4 credits3SS. Panke, Y. Benenson, P. S. Dittrich, M. Fussenegger, A. Hierlemann, M. H. Khammash, A. Moor, D. J. Müller, M. Nash, R. Platt, J. Stelling, B. Treutlein
AbstractThis course provides an overview of modern concepts of bioengineering across different levels of complexity, from single molecules to systems, microscaled reactors to production environments, and across different fields of applications
ObjectiveStudents will be able to recognize major developments in bioengineering across different organisms and levels of complexity and be able to relate it to major technological and conceptual advances in the underlying sciences.
ContentMolecular and cellular engineering; Synthetic biology: Engineering strategies in biology; from single molecules to systems; downscaling bioengineering; Bioengineering in chemistry, pharmaceutical sciences, and diagnostics, personalized medicine.
Lecture notesHandouts during class
LiteratureWill be announced during the course
CompetenciesCompetencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Personal CompetenciesCritical Thinkingassessed
636-0102-10LAdvanced Bioengineering
Only for Biotechnologie Master, Programme Regulations 2021 or doctoral students of D-BSSE
2 credits3SS. Panke, Y. Benenson, P. S. Dittrich, M. Fussenegger, A. Hierlemann, M. H. Khammash, A. Moor, D. J. Müller, M. Nash, R. Platt, J. Stelling, B. Treutlein
AbstractThis course provides an overview of modern concepts of bioengineering across different levels of complexity, from single molecules to systems, microscaled reactors to production environments, and across different fields of applications
ObjectiveStudents will be able to recognize major developments in bioengineering across different organisms and levels of complexity and be able to relate it to major technological and conceptual advances in the underlying sciences.
ContentMolecular and cellular engineering; Synthetic biology: Engineering strategies in biology; from single molecules to systems; downscaling bioengineering; Bioengineering in chemistry, pharmaceutical sciences, and diagnostics, personalized medicine.
Lecture notesHandouts during class
LiteratureWill be announced during the course
CompetenciesCompetencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Personal CompetenciesCritical Thinkingassessed
636-0550-00LBiomolecular Nanotechnology4 credits2V + 1UM. Nash
AbstractBiomolecular nanotechnology is a broad field that focuses on the study and science of biological materials including DNA, RNA and proteins at length scales below 10 nm. This is a broad overview of the topic with a focus on current research themes.
ObjectiveThe objective is to familiarise the students with a broad range of topics related to biotechnology, nanotechnology, and biophysics with a focus on current research and reading of scientific literature.
ContentIntroduction to biomacromolecules; Measurement techniques for characterisation of biomacromolecules; Fundamentals of molecular recognition; Recombinant DNA; Protein engineering; Directed evolution; Protein folding; Polymers; Elastin-like polypeptides; Intelligent materials; Spatially localized hydrogels; Mechanical properties of proteins and macromolecules; Single-molecule force spectroscopy
LiteratureRepresentative literature:
(1) Alberts, Molecular Biology (Ch.2 Cellular chemistry).
(2) Ratner, Biomaterials Science (Ch. 2.3, 2.4 Polymers & hydrogels).
(3) Walsh, Protein Biochemistry, (Ch. 2, Protein Structure).
(4) Nath et. al. Analytical chemistry, 74(3): 504-509, 2002.
(5) DeMonte, D., et. al. Proteins DOI: 10.1002/prot.24320, 2013.
(6) Feldhaus, M.J., et al. Nature Biotechnology 21 (2): 163–70, 2003.
(7) Link, A.J., et al. PNAS 103 (27): 10180–85, 2006.
(8) Chen, I. et al. PNAS 108 (28): 11399–404, 2011.
(9) Marín-Navarro, J., et. al. PloS One 10 (12). journals.plos.org: e0144289, 2015.
(10) Christensen, T. et al. Biomacromolecules 14 (5): 1514–19, 2013.
(11) Shimoboji, T., et al. PNAS. 99(26): 16592-16596, 2002.
(12) Puchner, E.M. et al. PNAS. 105(36): 13385–13390, 2008.
(13) Dietz, H., et al. PNAS 103 (5): 1244–47, 2006.