Bernhard Pfeiffer: Catalogue data in Spring Semester 2023 |
| Name | Dr. Bernhard Pfeiffer |
| Address | Inst. f. Pharmazeutische Wiss. ETH Zürich, HCI H 492.4 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 74 37 |
| Fax | +41 44 633 13 69 |
| bernhard.pfeiffer@pharma.ethz.ch | |
| Department | Chemistry and Applied Biosciences |
| Relationship | Lecturer |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 535-0226-00L | Pharmaceutical Analytics II  | 4 credits | 3G | C. Steuer, B. Pfeiffer | |
| Abstract | This course provides the basic concepts of pharmaceutical analytics in the context of pharmacopeial regulation by Ph. Eur and Ph. Helv. | ||||
| Learning objective | Students will be able to perform the following tasks: Explanation of the most important analytical techniques for the identification, purity testing and content determination of active pharmaceutical ingredients and excipients presented in Ph. Eur., USP, JP, andPh. Helv.) Analysis and spectral data interpretation of active pharmaceutical ingredients and excipients Explain and compare most important analytical techniques for pharmacies and pharmaceutical industry | ||||
| Content | Knowledge in pharmaceutical analytics to fulfill regulatory equirements in pharmaceutical industry based on the pharmacopeia in force. Focus is set on spectroscopic methods, mass specetrometry and chromatographic techniques for qualification, identification, purity testing and content determination of active pharmaceutical ingredients and excipients. | ||||
| Lecture notes | The slides of the lectures will be provided | ||||
| Literature | Instrumentelle Analytik, G. Rücker, M. Neugebauer, G.G. Willems; Deutscher Apotheker Verlag, Stuttgart Arzneistoffanalyse; H. J. Roth, K. Eger, R. Troschütz; Deutscher Apotheker Verlag, Stuttgart Introduction to Pharmaceutical Chemical Analysis; S.H. Hansen, S. Pedersen-Bjergaard, K. Rasmussen; Wiley & Sons | ||||
| Prerequisites / Notice | Requirements for the practical course Pharmaceutical Analytics: SR 2013: 6 credits Analytical/Pharmaceutical Analytics I/II or 36 credits of compulsory lectures 2nd year SR 2020: 7 credits Pharmaceutical Analytics I and II or 36 credits of compulsory lectures 2nd year | ||||
| 535-0349-00L | Laboratory Course Pharmaceutical Biology | 3 credits | 6P | B. Pfeiffer, B. Falch | |
| Abstract | Microscopic analysis of plant material (pharmacopoeia). Chromatographic analysis of medicinal plants, extraction methods, qualitative/quantitative determination of medicinal plant constituents, isolation of natural products, identification/purity determination of herbal drugs and natural products by means of spectroscopic, chemical, and chromatographic methods. | ||||
| Learning objective | Ability to perform phytochemical work at the practical level, knowledge and understanding of the qualitative and quantitative methods available for the analytical characterization of medicinal plants and plant extracts. Understanding the physical, chemical, and chromatographic behaviour of different classes of natural products, such as, e. g., flavonoids. alkaloids, essential oils etc. | ||||
| Content | Microscopic analysis of plant material (in particular with reference to pharmacopoeia specifications). Chromatographic analysis of medicinal plants, different extraction methods, qualitative and quantitative determination of medicinal plant constituents, isolation of natural products, identification and purity determination of herbal drugs and natural products by means of physical, spectroscopic, chemical, and chromatographic methods. | ||||
| Lecture notes | Will be provided at the beginning of the course. | ||||
| Literature | O. Sticher, J. Heilmann, I. Zündorf: Hänsel/Sticher Pharmakognosie Phytopharmazie, 10. Auflage 2014, Wissenschaftliche Verlagsgesellschaft, Stuttgart. Auch möglich: 9. Auflage 2009 (R. Hänsel, O. Sticher: Pharmakognosie Phytopharmazie, Springer Verlag, Berlin) oder 8. Auflage 2007 (R. Hänsel, O. Sticher: Pharmakognosie Phytopharmazie, Springer Verlag, Berlin) - H. Wagner, S. Bladt, Plant Drug Analysis. A Thin Layer Chromatography Atlas, Springer, 1996. - K.P. Adam, H. Becker, Analytik biogener Arzneistoffe, Wiss. Verlagsges. mbH Stuttgart, 2000. - W. Eschrich, Pulver-Atlas der Drogen, 9. Auflage, Deutscher Apotheker Verlag, Stuttgart, 2009. | ||||
| Prerequisites / Notice | Requirements: Laboratory course in Pharmaceutical Analytics passed Lecture in Pharmaceutical Bioloyg in the preceding semester or earlier | ||||