Paolo Arosio: Katalogdaten im Herbstsemester 2019 |
| Name | Herr Prof. Dr. Paolo Arosio |
| Lehrgebiet | Bioingenieurwissenschaften |
| Adresse | Professur Bioingenieurwissenschaft ETH Zürich, HCI F 129 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
| Telefon | +41 44 633 94 40 |
| paolo.arosio@chem.ethz.ch | |
| Departement | Chemie und Angewandte Biowissenschaften |
| Beziehung | Ausserordentlicher Professor |
| Nummer | Titel | ECTS | Umfang | Dozierende | |
|---|---|---|---|---|---|
| 529-0615-00L | Biochemical and Polymer Reaction Engineering Only for Chemical and Bioengineering MSc, Programme Regulations 2005. IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. | 7 KP | 3G | P. Arosio | |
| Kurzbeschreibung | Polymerization reactions and processes. Homogeneous and heterogeneous (emulsion) kinetics of free radical polymerization. Post treatment of polymer colloids. Bioprocesses for the production of molecules and therapeutic proteins. Kinetics and design of aggregation processes of macromolecules and proteins. | ||||
| Lernziel | The aim of the course is to learn how to design polymerization reactors and bioreactors to produce polymers and proteins with the specific product qualities that are required by different applications in chemical, pharmaceutical and food industry. This activity includes the post-treatment of polymer latexes, the downstream processing of proteins and the analysis of their colloidal behavior. | ||||
| Inhalt | We will cover the fundamental processes and the operation units involved in the production of polymeric materials and proteins. In particular, the following topics are discussed: Overview on the different polymerization processes. Kinetics of free-radical polymerization and use of population balance models. Production of polymers with controlled characteristics in terms of molecular weight distribution. Kinetics and control of emulsion polymerization. Surfactants and colloidal stability. Aggregation kinetics and aggregate structure in conditions of diffusion and reaction limited aggregation. Modeling and design of colloid aggregation processes. Physico-chemical characterization of proteins and description of enzymatic reactions. Operation units in bioprocessing: upstream, reactor design and downstream. Industrial production of therapeutic proteins. Characterization and engineering of protein aggregation. Protein aggregation in biology and in biotechnology as functional materials. | ||||
| Skript | Scripts are available on the web page of the Arosio-group: http://www.arosiogroup.ethz.ch/education.html Additional handout of slides will be provided during the lectures. | ||||
| Literatur | R.J. Hunter, Foundations of Colloid Science, Oxford University Press, 2nd edition, 2001 D. Ramkrishna, Population Balances, Academic Press, 2000 H.W. Blanch, D. S. Clark, Biochemical Engineering, CRC Press, 1995 | ||||
| 529-0615-01L | Biochemical and Polymer Reaction Engineering IMPORTANT NOTICE for Chemical and Bioengineering students: There are two different version of this course for the two regulations (2005/2018), please make sure to register for the correct version according to the regulations you are enrolled in. Please do not register for this course if you are enrolled in regulations 2005. | 6 KP | 3G | P. Arosio | |
| Kurzbeschreibung | Polymerization reactions and processes. Homogeneous and heterogeneous (emulsion) kinetics of free radical polymerization. Post treatment of polymer colloids. Bioprocesses for the production of molecules and therapeutic proteins. Kinetics and design of aggregation processes of macromolecules and proteins. | ||||
| Lernziel | The aim of the course is to learn how to design polymerization reactors and bioreactors to produce polymers and proteins with the specific product qualities that are required by different applications in chemical, pharmaceutical and food industry. This activity includes the post-treatment of polymer latexes, the downstream processing of proteins and the analysis of their colloidal behavior. | ||||
| Inhalt | We will cover the fundamental processes and the operation units involved in the production of polymeric materials and proteins. In particular, the following topics are discussed: Overview on the different polymerization processes. Kinetics of free-radical polymerization and use of population balance models. Production of polymers with controlled characteristics in terms of molecular weight distribution. Kinetics and control of emulsion polymerization. Surfactants and colloidal stability. Aggregation kinetics and aggregate structure in conditions of diffusion and reaction limited aggregation. Modeling and design of colloid aggregation processes. Physico-chemical characterization of proteins and description of enzymatic reactions. Operation units in bioprocessing: upstream, reactor design and downstream. Industrial production of therapeutic proteins. Characterization and engineering of protein aggregation. Protein aggregation in biology and in biotechnology as functional materials. | ||||
| Skript | Scripts are available on the web page of the Arosio-group: http://www.arosiogroup.ethz.ch/education.html Additional handout of slides will be provided during the lectures. | ||||
| Literatur | R.J. Hunter, Foundations of Colloid Science, Oxford University Press, 2nd edition, 2001 D. Ramkrishna, Population Balances, Academic Press, 2000 H.W. Blanch, D. S. Clark, Biochemical Engineering, CRC Press, 1995 | ||||
| 529-0632-00L | Homogeneous Reaction Engineering | 4 KP | 3G | P. Arosio, T. Casalini | |
| Kurzbeschreibung | Homogene Reaktionstechnik, Ideale Reaktoren: Optimierung von Umsatz und Selektivitaet komplexer kinetischer Netzwerke. Waermeeffekte in chemischen Reaktoren. Verweilzeitverteilungen. Analyse und Auslegung chemischer Reaktoren. Schnelle Reaktionen in turbulenter Stroemung. Sensitivitaet und Stabilitaet chemischer Reaktoren. | ||||
| Lernziel | Bereitstellung einer kompletten Methodologie fuer die Analyse und Auslegung homogener Reaktoren | ||||
| Inhalt | Kinetische Modelle für homogene Reaktionen. Ermittlung und Analyse experimenteller Geschwindigkeitsdaten. Isotherme ideale Reaktoren. Komplexe Reaktionsnetzwerke. Reaktordesign zur Umsatz- und Selektivitätsoptimierung. Adiabatische und nicht-isotherme Reaktoren. Temperatureffekte auf reversible Reaktionen. Verweilzeitverteilung in chemischen Reaktoren. Mischungseffekte in reagierenden Systemen. Design realer Reaktoren. Parametrische Sensitivitaet und Reaktorstabilität. | ||||
| Skript | Skripte stehen auf der Website der Gruppe Morbidelli zur Verfuegung | ||||
| Literatur | H.S. Fogler, Elements of Chemical Reaction Engineering, Prentice Hall, 3rd edition, 1999 O. Levenspiel, Chemical Reaction Engineering, John Wiley, 3rd edition, 1999 J. Baldyga and J.R. Bourne, Turbulent Mixing and Chemical Reactions, John Wiley, 1999 A. Varma, M. Morbidelli and H. Wu, Parametric Sensitivity in Chemical Systems, Cambridge University Press, 1999 A. Varma and M. Morbidelli, Mathematical Methods in Chemical Engineering, Oxford University Press, 1997 | ||||
| 529-0690-00L | ICB Seminars on Chemical and Biochemical Engineering  | 1 KP | P. Arosio | ||
| Kurzbeschreibung | The ICB seminar series covers the umbrella of diverse research activities encompassed within the institute, including catalysis, functional materials, polymer engineering, separations, microfluidics, process design, and systems engineering. This series was founded with the aim or promoting cross-disciplinary scientific discourse and interaction with other distinguished groups working worldwide. | ||||
| Lernziel | Students are expected to attend all seminars in one academic year, and should register at the beginning of each seminar. Additionally they must deliver a two page written report at the end of the year describing the topics covered, main conclusions, and interrelationships between the different themes. | ||||
| Inhalt | The ICB seminar series covers the umbrella of diverse research activities encompassed within the institute, including catalysis, functional materials, polymer engineering, separations, microfluidics, process design, and systems engineering. This series was founded with the aim or promoting cross-disciplinary scientific discourse and interaction with other distinguished groups working worldwide, and is targeted at individuals who have made outstanding contributions within their fields. Each year, around 7 distinguished scientists and technologists will be invited to speak on topics of current interest in Chemical and Biochemical Engineering. PhD students are particularly encouraged to attend in order to broaden their perception and enrich their scientific horizons. | ||||