|Prof. Dr. Emma Wetter Slack
Dep. Gesundheitswiss. und Technol.
ETH Zürich, HCI E 365.1
|+41 44 632 45 91
|Experimental and Computational Approaches to Study Host Immune-Microbiota Interactions
Number of participants limited to 9.
The enrolment is done by the D-BIOL study administration.
|E. Wetter Slack, S. Sunagawa
|Laboratory research project. Groups of 3 students will carry out research projects on a currently unanswered topic in host immune-microbiota interactions and will analyse next-generation sequencing data.
|Introduction to current experimental and computational research methods in the fields of mucosal immunology and gut microbiota. Practical experience of work in a laboratory and an introduction to planning experiments to address given hypotheses. Gain skills in computational data analysis and in presenting ation for oral and written reports. Lectures introducing mucosal immunology and intestinal microbiology. Start to assess current literature. Assessment by written and oral presentation of the project and written exam.
|Research project on the theme immune system-microbiota interactions.
|Will be provided for each project separately.
|M. Kopf, S. R. Leibundgut, A. Oxenius, E. Wetter Slack, further lecturers
|Introduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity)
|The lectures will provide a detailed understanding:
- how innate and adaptive immune responses interact at the cellular and molecular level.
- how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites.
- why lymphocytes tolerate self molecules.
- about function and dysfunction the intestinal immune system.
- immunopathology and inflammatory diseases.
|The aim of lecture is to understand:
> How pathogens are recognized by the innate immune system
> Immune defense against various pathogens
> Immunology of the skin, lung and intestines
> Tumor immunology
> Migration and homing of immune cells
> tolerance and autoimmunity
> T cell memory
|Presentations of the lecturers are available at the Moodle link
|Recommended: Kuby Immunology (Freeman)