Martin Pilhofer: Catalogue data in Autumn Semester 2018 |
| Name | Prof. Dr. Martin Pilhofer |
| Field | Cryo-Electron Microscopy |
| Address | Inst. f. Molekularbiol.u.Biophysik ETH Zürich, HPK F 13 Otto-Stern-Weg 5 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 39 63 |
| pilhofer@mol.biol.ethz.ch | |
| Department | Biology |
| Relationship | Full Professor |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 551-0313-00L | Microbiology (Part I) | 3 credits | 2V | W.‑D. Hardt, L. Eberl, H.‑M. Fischer, J. Piel, M. Pilhofer | |
| Abstract | Advanced lecture class providing a broad overview on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | ||||
| Learning objective | This concept class will be based on common concepts and introduce to the enormous diversity among bacteria and archaea. It will cover the current research on bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | ||||
| Content | Advanced class covering the state of the research in bacterial cell structure, genetics, metabolism, symbiosis and pathogenesis. | ||||
| Lecture notes | Updated handouts will be provided during the class. | ||||
| Literature | Current literature references will be provided during the lectures. | ||||
| Prerequisites / Notice | English The lecture "Grundlagen der Biologie II: Mikrobiologie" is the basis for this advanced lecture. | ||||
| 551-1403-00L | Imaging Bacterial Cells in a Native State by Electron Cryotomography  Number of participants limited to 5. The enrolment is done by the D-BIOL study administration. | 6 credits | 7G | M. Pilhofer | |
| Abstract | The goal is to acquire the techniques to image bacteria by electron cryotomography, resolving their structure in a native state, in 3D, and to macromolecular resolution. In a small group, students will perform wet lab experiments, data collection with stat-of-the-art equipment, data processing and analyses. The key method and its application in bacterial cell biology will be introduced by lectures | ||||
| Learning objective | Students will acquire the skills to cultivate bacteria, plunge-freeze samples for cryotomography, collect data using an electron cryomicroscope, process raw data, analyze tomograms, perform subtomogram averaging, model structures of interest, and generate movies for visualization. https://www.mol.biol.ethz.ch/groups/pilhofer_group/ | ||||
| 551-1405-00L | Electron Cryomicroscopy Seminar | 0 credits | 0.5S | M. Pilhofer, further lecturers | |
| Abstract | Intergroup seminar for scientists and students interested in electron cryomicroscopy | ||||
| Learning objective | The goal of the seminar is to provide an exchange forum for anyone interested in electron cryomicroscopy (tomography and single particle). The first ~10 minutes are used for exchange on instrument status and technical issues, followed by a ~30 min presentation and discussion of a specific project. The seminar can also be used to discuss current literature and report from conferences. | ||||
| Prerequisites / Notice | Presented project data are confidential. Sign-up for seminar announcements by emailing pilhofer@biol.ethz.ch. | ||||
| 551-1411-00L | Molecular and Structural Biology III: Current Topics The course will only take place with a minimum of 6 participants. | 2 credits | 1V | K. Locher, F. Allain, N. Ban, R. Glockshuber, M. Pilhofer, E. Weber-Ban | |
| Abstract | The course discusses current topics and cutting edge research in the structural, molecular, and biochemical study of cellular macromolecules. Student participation is an essential component of the course and will contribute to the exam grade | ||||
| Learning objective | The goal is to discuss cutting edge research in the structural, molecular, and biochemical study of cellular macromolecules. Students will also have an opportunity to present and discuss recent breakthroughs relevant to the research fields presented by the faculty teaching the course (see http://www.mol.biol.ethz.ch/research.html for details on the topics). | ||||
| Literature | Will be distributed by the instructors | ||||
| 551-1619-00L | Structural Biology | 1 credit | 1K | R. Glockshuber, F. Allain, N. Ban, K. Locher, M. Pilhofer, E. Weber-Ban, K. Wüthrich | |
| Abstract | The course consists of a series of research seminars on Structural Biology, Biochemistry and Biophysics, given by both scientists of the National Center of Competence in Research (NCCR) in Structural Biology and external speakers. Information on the individual seminars is provided on the following websites: http://www.structuralbiology.uzh.ch/educ002.asp http://www.biol.ethz.ch/dbiol-cal/index | ||||
| Learning objective | The goal of this course is to provide doctoral and postdoctoral students with a broad overview on the most recent developments in biochemistry, structural biology and biophysics. | ||||