Joao Fernandes de Matos: Catalogue data in Autumn Semester 2019 |
Name | Dr. Joao Fernandes de Matos |
Field | Cellular Biochemistry |
Department | Biology |
Relationship | Assistant Professor |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
551-0103-AAL | Fundamentals of Biology II: Cell Biology Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 5 credits | 11R | E. Hafen, J. Fernandes de Matos, U. Kutay, G. Schertler, U. Suter, S. Werner | |
Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Learning objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | ||||
Literature | Alberts et al. 'Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback). Topic/Lecturer/Chapter/Pages: Analyzing cells & molecules / Gebhard Schertler/8/ 439-463; Membrane structure / Gebhard Schertler/ 10/ 565-595; Compartments and Sorting/ Ulrike Kutay/12+14+6/641-694/755-758/782-783/315-320/325 -333/Table 6-2/Figure6-20, 6-21, 6-32, 6-34; Intracellular Membrane Traffic/ Ulrike Kutay/13/695-752; The Cytoskeleton/ Ulrike Kutay/ 16/889 - 948 (only the essentials); Membrane Transport of Small Molecules and the Electrical Properties of Membranes /Sabine Werner/11/597 - 633; Mechanisms of Cell Communication / Sabine Werner/15/813-876; Cancer/ Sabine Werner/20/1091-1141; Cell Junctions and Extracellular Matrix/Ueli Suter / 1035-1081; Stem Cells and Tissue Renewal/Ueli Suter /1217-1262; Development of Multicellular organisms/ Ernst Hafen/ 21/ 1145-1179 /1184-1198/1198-1213; Cell Migration/Joao Matos/951-960; Cell Death/Joao Matos/1021-1032; Cell Cycle/chromosome segregation/Cell division/Meiosis/Joao Matos/ 963-1018. | ||||
Prerequisites / Notice | none | ||||
551-0103-00L | Fundamentals of Biology II: Cell Biology | 5 credits | 5V | S. Werner, J. Fernandes de Matos, U. Kutay, G. Schertler, U. Suter, I. Zemp | |
Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Learning objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | ||||
Lecture notes | The lectures are presented in the Powerpoint format. These are available on the WEB for ETH students over the nethz (Moodle). Some lectures are available on the ETH WEB site in a live format (Livestream) at the above WEB site. | ||||
Literature | The lectures follow Alberts et al. `Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback). | ||||
Prerequisites / Notice | Some of the lectures are given in the English language. Certain sections of the text-book must be studied by self-instruction. | ||||
551-0530-00L | Repair, Recombination, Replication | 0 credits | 1K | J. Fernandes de Matos | |
Abstract | Several research groups from University, ETH, Basel, Bern and Konstanz meet once per month and present their work related to DNA-repair, recombination, replication, and cancer. | ||||
Learning objective | Discussion of current topics in DNA-repair, recombination, replication, and cancer. | ||||
Content | Discussion of current topics in DNA-repair, recombination, replication, and cancer. | ||||
Lecture notes | no script | ||||
551-1303-00L | Cellular Biochemistry of Health and Disease Number of participants limited to 20. | 4 credits | 2S | V. Korkhov, Y. Barral, J. Fernandes de Matos, T. Ishikawa, R. Kroschewski, M. Peter, P. Picotti, A. E. Smith, B. Snijder, K. Weis | |
Abstract | During this Masters level seminar style course, students will explore current research topics in cellular biochemistry focused on the structure, function and regulation of selected cell components, and the consequences of dysregulation for pathologies. | ||||
Learning objective | Students will work with experts toward a critical analysis of cutting-edge research in the domain of cellular biochemistry, with emphasis on normal cellular processes and the consequences of their dysregulation. At the end of the course, students will be able to introduce, present, evaluate, critically discuss and write about recent scientific articles in the research area of cellular biochemistry. | ||||
Content | Guided by an expert in the field, students will engage in classical round-table style discussions of current literature with occasional frontal presentations. Students will alternate as discussion leaders throughout the semester, with the student leader responsible to briefly summarize key general knowledge and context of the assigned primary research paper. Together with the faculty expert, all students will participate in discussion of the primary paper, including the foundation of the biological question, specific questions addressed, key methods, key results, remaining gaps and research implications. | ||||
Literature | The literature will be provided during the course | ||||
Prerequisites / Notice | The course will be taught in English. |