Oliver Ullrich: Catalogue data in Autumn Semester 2020

Name Prof. Dr. Oliver Ullrich
Address
Universität Zürich
Winterthurerstrasse 190
Anatomisches Institut
8057 Zürich
SWITZERLAND
Telephone044 635 53 11
E-mailoliver.ullrich@hest.ethz.ch
URLhttp://www.spacehub.uzh.ch
DepartmentInformation Technology and Electrical Engineering
RelationshipLecturer

NumberTitleECTSHoursLecturers
227-0981-00LCross-Disciplinary Research and Development in Medicine and Engineering Restricted registration - show details
A maximum of 12 medical degree students and 12 (biomedical) engineering degree students can be admitted, their number should be equal.
4 credits2V + 2AV. Kurtcuoglu, D. de Julien de Zelicourt, M. Meboldt, M. Schmid Daners, O. Ullrich
AbstractCross-disciplinary collaboration between engineers and medical doctors is indispensable for innovation in health care. This course will bring together engineering students from ETH Zurich and medical students from the University of Zurich to experience the rewards and challenges of such interdisciplinary work in a project based learning environment.
ObjectiveThe main goal of this course is to demonstrate the differences in communication between the fields of medicine and engineering. Since such differences become the most evident during actual collaborative work, the course is based on a current project in physiology research that combines medicine and engineering. For the engineering students, the specific aims of the course are to:

- Acquire a working understanding of the anatomy and physiology of the investigated system;
- Identify the engineering challenges in the project and communicate them to the medical students;
- Develop and implement, together with the medical students, solution strategies for the identified challenges;
- Present the found solutions to a cross-disciplinary audience.
ContentAfter a general introduction to interdisciplinary communication and detailed background on the collaborative project, the engineering students will team up with medical students to find solutions to a biomedical challenge. In the process, they will be supervised both by lecturers from ETH Zurich and the University of Zurich, receiving coaching customized to the project. The course will end with each team presenting their solution to a cross-disciplinary audience.
Lecture notesHandouts and relevant literature will be provided.
377-0107-00LNervous System Restricted registration - show details
Only for Human Medicine BSc
5 credits5VD. P. Wolfer, I. Amrein, J. Bohacek, D. Burdakov, G. Schratt, L. Slomianka, O. Ullrich, N. Wenderoth, further lecturers
AbstractStructure and function of the central and peripheral nervous system including its major disorders.
ObjectiveUpon successful completion of this module, students should be able to:
1. distinguish important cell types of the nervous system (neurons, glial cells) on the basis of their structure and function;
2. correctly describe neurophysiological basics of stimulus conduction and processing in the peripheral and central nervous system;
3. correctly name the organ structures and circuits involved in the development of the peripheral and central nervous system;
4. associate the different brain areas with corresponding functions in homeostasis, sensory, motor and cognitive functions;
5. identify clinical pictures associated with the loss of function of certain structures of the central and peripheral nervous system and to understand the mode of action of current therapeutic approaches.
ContentIn this module, students get an overview of the structure (anatomy) and function (physiology) of the peripheral and central nervous system as well as of selected neurological diseases (pathophysiology).

The module is subdivided into a total of six thematic areas:

1. Basics of neurophysiology, stimulus conduction and processing using the example of the motor end plate, peripheral nervous system, associated clinical pictures (myasthenia gravis);

2. Structure, circuits and pathways in the spinal cord, spinal nerves, motor stimulus conduction in the spinal cord, spinal cord lesions and pain;

3. Anatomy and function of the brain stem and cranial nerves and their significance for motor and sensory functions, lesions (brain stem syndromes);

4. Anatomy and function of basal ganglia, thalamus and hypothalamus, control of the autonomic nervous system (homeostasis, food and water intake), basal ganglia defects using Parkinson's disease as an example;

5. Anatomy and function of the cerebellum and vestibular system, fine control of motor functions, associative learning, cerebellar symptoms (ataxias), organ of equilibrium;

6. Anatomy and function of the cerebrum, sensory and motor processing, cognition, learning and memory, neurodegenerative (Alzheimer) and neuropsychiatric (schizophrenia) disorders.
377-0301-11LBlood, Immune System Restricted registration - show details
Only for Human Medicine BSc
4 credits5VF. Sallusto, L. Flatz, G. Guarda, M. G. Manz, A. Theocharides, O. Ullrich, further lecturers
AbstractThis course will focus on the components and functions of the hematopoietic and the immune systems and on diseases affecting or caused by these systems.
Objective1. The organization and development of hematopoiesis including hematopoietic stem cell development; the role of hematopoietic growth and transcription factors in hematopoiesis; the role of hemoglobin in health and disease; erythrocyte physiology and iron metabolism; the principles of blood groups and blood transfusions; the principles of coagulation and the pharmacology of coagulation; the role of platelets and pharmacological platelet inhibition; to define thrombophilia and to understand thrombotic events; the role of leukocytes in health and disease; the analysis of blood samples; the principles of hematopoietic stem cell transplantation.
2. The development of the immune system; the structure and function of primary and secondary lymphoid organs; the cellular and molecular mechanisms of the innate and adaptive immune systems; the effector mechanisms of immune responses against pathogens; basic concepts of immune-mediated diseases (allergy and autoimmunity), tumor immunology, immunodeficiency, organ transplantation; basic knowledge of therapies.
Content1. Introduction to hematopoiesis, hematopoietic growth factors, hematopoietic transcription factors, erythrocyte physiology, blood groups, blood transfusion, iron metabolism, platelets, coagulation cascade, fibrinolysis, hemoglobin, hemoglobinopathies, leukocytes (granulocytes, monocytes), clinical presentation of neutropenia, pharmacology of hemostasis, clinical presentation of thrombophilia, basics of hematopoietic stem cell transplantation, some aspects of laboratory medicine in hematology, virtual microscopy of blood and bone marrow smears.
2. Structure and anatomical position of primary and secondary lymphoid organs, cells and molecules of the innate immune system, T and B cell development and receptor diversity, major histocompatibility complex (MHC) and antigen presentation, effector B cells and antibodies, effector T cells, regulatory T cells and cytokines, allergy and hypersensitivities, autoimmunity and anti-inflammatory drugs, transplantation and immunosuppressive drugs, immunodeficiency, immune response in cancer and immunotherapies.
Lecture notesThe course is supported by a Moodle page through which students have access to all necessary documentation.
LiteratureThe essential course material will be available on the course's Moodle Page in the form of lesson handouts
Suggested reference books include:
Blood:
Hoffbrand's Essential Haematology
Immune system:
Herbert Hof, Rüdiger Dörries; unter Mitarbeit von: Gernot Geginat, Dirk Schlüter und Constanze Wendt Medizinische Mikrobiologie Thieme 2017
http://www.library.ethz.ch/DADS:default_scope:ebi01_prod010873047
Abbas AK, Lichtman AH, Pillai S. Basic Immunology: Functions and Disorders of the Immune System, 5th ed.
W. B. Saunders Co., 2016;
https://institut.elsevierelibrary.de/product/basic-immunology85281
Prerequisites / NoticeThe Immune system part of this course builds on the content of the "Infection and Immunology" course.
377-0311-00LClinical Anatomy Lab Restricted registration - show details
Only for Human Medicine BSc
5 credits7PJ. Loffing, O. Ullrich, I. Amrein, G. Colacicco, N. Lier, further lecturers
AbstractTopographical Anatomy and Radioanatomy of the head, skull, central nervous system, neck and neck organs, upper and lower extremities, thoracic wall and organs, abdominal wall and organs, pelvis and pelvic organs, dorsal muscles, vessels, nerves, functions, clinical aspects. Methods: Anatomical dissection of human bodies.
ObjectiveLearning and understnding of the detailed composition and function of the healty human body and ist components. Learning of selected examples of relevant radiographic anatomy and their implication in clinical medical work.
ContentTopographic – and radiographic anatomy of selected anatomical regions. Students dissect these regions and discuss important clinical content with aid of assistents.
Prerequisites / NoticeVoraussetzungen:
LE 377-0105-00L Bewegungsapparat
LE 377-0107-00L Nervensystem
LE 377-0201-00L Herz-Kreislauf-System
LE 377-0203-00L Atmungs-System
LE 377-0205-00L Nieren und Homöostase