Jan Alexander Hiss: Catalogue data in Autumn Semester 2018

Name	Dr. Jan Alexander Hiss
Address	Inst. f. Pharmazeutische Wiss. ETH Zürich, HCI G 492.5 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND
Telephone	+41 44 633 73 75
Fax	+41 44 633 13 79
E-mail	jan.hiss@pharma.ethz.ch
URL	http://www.cadd.ethz.ch
Department	Chemistry and Applied Biosciences
Relationship	Lecturer

Number	Title	ECTS	Hours	Lecturers
511-0007-00L	Scientific Writing and Presenting Only for Pharmaceutical Sciences MSc.	2 credits	2G	G. Schneider, J. Dolenc, J. A. Hiss, J.‑C. Leroux, O. Renn, J. Schnabl
Abstract	This introductory class provides an overview of the basic scientific writing techniques and a guideline to presenting scientific data, together with guided exercises and hands-on training. It is devised to accompany the research projects within the curriculum of the MSc in Pharmaceutical Sciences.
Learning objective	The class enables the participants to prepare their own scientific texts and oral presentations, and critically assess the quality of the presentation of scientific data.
Content	The participants receive an introduction to basic formal aspects of scientific writing and the design of graphical elements. Lectures and topical seminars alternate with practical task for the participants, which will be evaluated in a peer-to-peer setting. Performance feedback is provided by both the teachers and the peers.
535-0023-00L	Computer-Assisted Drug Design (Practical Course) Limited number of participants.	4 credits	6P	G. Schneider, J. A. Hiss
Abstract	The practical course is open for master and graduate students to get an introduction into hands-on computer-assisted drug design. The class includes an introduction to computer-based screening of a virtual compound library, subsequent synthesis of candidate ligands, and biochemically testing for activity on pharmacologically important drug targets.
Learning objective	Participants become familiar with state-of-the-art methodologies in a real-life computer-aided medicinal chemistry project. Participants work as small teams, perform literature research and discuss recent research findings. A seminar talk is to be given presenting the molecular design strategy chosen and the results obtained during the course.
Content	The course offers the possibility for people with and without computational and or laboratory background to get an introduction into computer-assisted drug design, as well as practical training in a modern chemical laboratory. Using various software suites, the participants will computationally create and screen a virtual compound library for potential active small molecules. The process will involve an introduction to screening a virtual compound library, synthesizing candidate inhibitors, and biophysical testing against a pharmacologically important drug target.
Lecture notes	Detailed information will be handed out during the course.
Literature	Textbook: Schneider, G. and Baringhaus, K.-H. (2008) Molecular Design - Concepts and Applications. Wiley-VCH, Weinheim, New York.
Prerequisites / Notice	The class is organized as a two-week block course. The number of participants is limited. Kick-off meeting and confirmation of registration (Vorbesprechung und Platzvergabe): During the last lecture of the class "Computer-Assisted Drug Design" (535-0022-00) Ideally, students interested in the course participated and successfully passed the lecture "Computer-Assisted Drug Design" (535-0022-00).