|Prof. Dr. Stephen J. Ferguson
Institut für Biomechanik
ETH Zürich, GLC H 15.2
Gloriastrasse 37/ 39
|+41 44 633 93 30
|Health Sciences and Technology
|Clinical Challenges in Musculoskeletal Disorders
|M. Leunig, S. J. Ferguson, Z.‑M. Manjaly
|This course reviews musculoskeletal disorders focusing on the clinical presentation, current treatment approaches and future challenges and opportunities to overcome failures.
|Appreciation of the surgical and technical challenges, and future perspectives offered through advances in surgical technique, new biomaterials and advanced medical device construction methods.
|Foot deformities, knee injuries, knee OA, hip disorders in the child and adolescent, hip OA, spine deformities, degenerative spine disease, shoulder in-stability, hand, rheumatoid diseases, neuromuscular diseases, sport injuries and prevention
|Practical Methods in Biofabrication
Number of participants limited to 12.
|M. Zenobi-Wong, S. J. Ferguson, S. Schürle-Finke
|Biofabrication involves the assembly of materials, cells, and biological building blocks into grafts for tissue engineering and in vitro models. The student learns techniques involving the fabrication and characterization of tissue engineered scaffolds and the design of 3D models based on medical imaging data. They apply this knowledge to design, manufacture and evaluate a biofabricated graft.
|The objective of this course is to give students hands-on experience with the tools required to fabricate tissue engineered grafts. During the first part of this course, students will gain practical knowledge in hydrogel synthesis and characterization, fuse deposition modelling and stereolithography, bioprinting and bioink design, electrospinning, and cell culture and viability testing. They will also learn the properties of common biocompatible materials used in fabrication and how to select materials based on the application requirements. The students learn principles for design of 3D models. Finally the students will apply their knowledge to a problem-based Project in the second half of the Semester. The Project requires significant time outside of class Hours, strong commitment and ability to work independently.
|Prerequisites / Notice
|Not recommended if passed 376-1622-00 Practical Methods in Tissue Engineering
|Finite Element Analysis in Biomedical Engineering
|S. J. Ferguson, B. Helgason
|This course provides an introduction to finite element analysis, with a specific focus on problems and applications from biomedical engineering.
|Finite element analysis is a powerful simulation method for the (approximate) solution of boundary value problems. While its traditional roots are in the realm of structural engineering, the methods have found wide use in the biomedical engineering domain for the simulation of the mechanical response of the human body and medical devices. This course provides an introduction to finite element analysis, with a specific focus on problems and applications from biomedical engineering. This domain offers many unique challenges, including multi-scale problems, multi-physics simulation, complex and non-linear material behaviour, rate-dependent response, dynamic processes and fluid-solid interactions. Theories taught are reinforced through practical applications in self-programmed and commercial simulation software, using e.g. MATLAB, ANSYS, FEBIO.
|(Theory) The Finite Element and Finite Difference methods
Gallerkin, weighted residuals, discretization
(Theory) Mechanical analysis of structures
Trusses, beams, solids and shells, DOFs, hand calculations of simple FE problems, underlying PDEs
(Application) Mechanical analysis of structures
Truss systems, beam systems, 2D solids, meshing, organ level analysis of bones
(Theory and Application) Mechanical analysis of structures
Micro- and multi-scale analysis, voxel models, solver limitations, large scale solvers
(Theory) Non-linear mechanical analysis of structures
Large strain, Newton-Rhapson, plasticity
(Application) Non-linear mechanical analysis of structures
Plasticity (bone), hyperelasticity, viscoelasticity
(Theory and Application) Contact analysis
Friction, bonding, rough contact, implants, bone-cement composites, pushout tests
(Theory) Flow in Porous Media
Potential problems, Terzhagi's consolidation
(Application) Flow in Porous Media
Confined and unconfined compression of cartilage
(Theory) Heat Transfer and Mass Transport
Diffusion, conduction and convection, equivalency of equations
(Application) Heat Transfer and Mass Transport
Sequentially-coupled poroelastic and transport models for solute transport
(Theory) Computational Biofluid Dynamics
Newtonian vs. Non-Newtonian fluid, potential flow
(Application) Computational Biofluid Dynamics
Flow between micro-rough parallel plates
|Handouts consisting of (i) lecturers' script, (ii) selected excerpts from relevant textbooks, (iii) selected excerpts from theory manuals of commercial simulation software, (iv) relevant scientific publications.
|Prerequisites / Notice
|Familiarity with basic numerical methods.
Programming experience with MATLAB.
|Colloquium in Biomechanics
|B. Helgason, S. J. Ferguson, R. Müller, J. G. Snedeker, B. Taylor, M. Zenobi-Wong
|Current topics in biomechanics presented by speakers from academia and industry.
|Getting insight into actual areas and problems of biomechanics.