Gisbert Schneider: Catalogue data in Autumn Semester 2022

Name	Prof. Dr. Gisbert Schneider
Field	Computer-Assisted Drug Design
Address	Dep. Biosysteme ETH Zürich, BSS F 57 Klingelbergstrasse 48 4056 Basel SWITZERLAND
Telephone	+41 44 633 73 27
Fax	+41 44 633 13 79
E-mail	gisbert.schneider@bsse.ethz.ch
URL	http://www.modlab.ethz.ch
Department	Chemistry and Applied Biosciences
Relationship	Full Professor

Number	Title	ECTS	Hours	Lecturers
535-0023-00L	Computer-Assisted Drug Design (Practical Course) Does not take place this semester. Limited number of participants.	4 credits	6P	G. Schneider
Abstract	The practical course is open for master and graduate students to get an introduction into hands-on computer-assisted drug design. The class includes an introduction to computer-based screening of a virtual compound library, subsequent synthesis of candidate ligands, and biochemically testing for activity on pharmacologically important drug targets.
Learning objective	Participants become familiar with state-of-the-art methodologies in a real-life computer-aided medicinal chemistry project. Participants work as small teams, perform literature research and discuss recent research findings. A seminar talk is to be given presenting the molecular design strategy chosen and the results obtained during the course.
Content	The course offers the possibility for people with and without computational and or laboratory background to get an introduction into computer-assisted drug design, as well as practical training in a modern chemical laboratory. Using various software suites, the participants will computationally create and screen a virtual compound library for potential active small molecules. The process will involve an introduction to screening a virtual compound library, synthesizing candidate inhibitors, and biophysical testing against a pharmacologically important drug target.
Lecture notes	Detailed information will be handed out during the course.
Literature	Textbook: Schneider, G. and Baringhaus, K.-H. (2008) Molecular Design - Concepts and Applications. Wiley-VCH, Weinheim, New York.
Prerequisites / Notice	The class is organized as a two-week block course. The number of participants is limited. Kick-off meeting and confirmation of registration (Vorbesprechung und Platzvergabe): During the last lecture of the class "Computer-Assisted Drug Design" (535-0022-00) Ideally, students interested in the course participated and successfully passed the lecture "Computer-Assisted Drug Design" (535-0022-00).
535-0024-00L	Methods in Drug Design Does not take place this semester. Complementary to the practical course "Computer-Assisted Drug Design (Practical Course)" 535-0023-00L . Compulsory for the students of the practical course, open for other interested students.	1 credit	1V	G. Schneider
Abstract	The lecture is organized as a two-week block during the practical course "Computer-Assisted Drug Design" (535-0023-00 P), totalling 10 two-hour lectures. It provides an introduction to advanced drug design techniques and approaches emphasizing computer-assisted molecular design.
Learning objective	Participants will learn about computational algorithms and advanced experimental approaches to drug discovery and design, including selected actual topics and practical applications. The contents of the lecture will allow for a deeper understanding of modern computer-assisted drug design methods and how they are linked to experimental applications. The main focus is on computational medicinal chemistry, so that participants will be able to use relevant computer-based methods in own research projects.
Literature	Schneider, G. and Baringhaus, K.-H. (2008) Molecular Design - Concepts and Applications. Wiley-VCH, Weinheim, New York. Additional selected literature will be provided during the lecture.
Prerequisites / Notice	The lecture is mandatory for all participants of the course "Computer-Assisted Drug Design" (535-0023-00 P).
535-0900-00L	Seminars on Drug Discovery and Development	1 credit	1K	R. Schibli, K. Eyer, C. Halin Winter, J. Hall, J.‑C. Leroux, U. Quitterer, G. Schneider, H. U. Zeilhofer
Abstract	State-of-the-art information on drug discovery and development by experts from academia and industry.
Learning objective	State-of-the-art information on drug discovery and development.
Content	Seminar series of the Institute of Pharmaceutical Sciences. Experts from academia and industry report on relevant topics.
535-2000-00L	Seminar for Group Members	0 credits	2S	G. Schneider
Abstract	Weekly group seminar, in which members of the research team present and discuss the results of their projects and selected reports from the current scientific literature.
Learning objective	Participants learn to present scientific studies and discuss own results in greater context.