Gisbert Schneider: Katalogdaten im Herbstsemester 2021 |  |
| Name | Herr Prof. Dr. Gisbert Schneider |
| Lehrgebiet | Computer-Assisted Drug Design |
| Adresse | Dep. Biosysteme ETH Zürich, BSS F 57 Klingelbergstrasse 48 4056 Basel SWITZERLAND |
| Telefon | +41 44 633 73 27 |
| Fax | +41 44 633 13 79 |
| gisbert.schneider@bsse.ethz.ch | |
| URL | http://www.modlab.ethz.ch |
| Departement | Chemie und Angewandte Biowissenschaften |
| Beziehung | Ordentlicher Professor |
| Nummer | Titel | ECTS | Umfang | Dozierende | |
|---|---|---|---|---|---|
| 535-0023-00L | Praktikum Computer-Assisted Drug Design  Findet dieses Semester nicht statt. Beschränkte Teilnehmerzahl. | 4 KP | 6P | G. Schneider | |
| Kurzbeschreibung | The practical course is open for master and graduate students to get an introduction into hands-on computer-assisted drug design. The class includes an introduction to computer-based screening of a virtual compound library, subsequent synthesis of candidate ligands, and biochemically testing for activity on pharmacologically important drug targets. | ||||
| Lernziel | Participants become familiar with state-of-the-art methodologies in a real-life computer-aided medicinal chemistry project. Participants work as small teams, perform literature research and discuss recent research findings. A seminar talk is to be given presenting the molecular design strategy chosen and the results obtained during the course. | ||||
| Inhalt | The course offers the possibility for people with and without computational and or laboratory background to get an introduction into computer-assisted drug design, as well as practical training in a modern chemical laboratory. Using various software suites, the participants will computationally create and screen a virtual compound library for potential active small molecules. The process will involve an introduction to screening a virtual compound library, synthesizing candidate inhibitors, and biophysical testing against a pharmacologically important drug target. | ||||
| Skript | Detailed information will be handed out during the course. | ||||
| Literatur | Textbook: Schneider, G. and Baringhaus, K.-H. (2008) Molecular Design - Concepts and Applications. Wiley-VCH, Weinheim, New York. | ||||
| Voraussetzungen / Besonderes | The class is organized as a two-week block course. The number of participants is limited. Kick-off meeting and confirmation of registration (Vorbesprechung und Platzvergabe): During the last lecture of the class "Computer-Assisted Drug Design" (535-0022-00) Ideally, students interested in the course participated and successfully passed the lecture "Computer-Assisted Drug Design" (535-0022-00). | ||||
| 535-0024-00L | Methods in Drug Design Findet dieses Semester nicht statt. Ergänzung zum "Praktikum Computer-Assisted Drug Design" 535-0023-00L, Pflicht für alle Praktikumsteilnehmer, offen für alle Interessierten. | 1 KP | 1V | G. Schneider | |
| Kurzbeschreibung | The lecture is organized as a two-week block during the practical course "Computer-Assisted Drug Design" (535-0023-00 P), totalling 10 two-hour lectures. It provides an introduction to advanced drug design techniques and approaches emphasizing computer-assisted molecular design. | ||||
| Lernziel | Participants will learn about computational algorithms and advanced experimental approaches to drug discovery and design, including selected actual topics and practical applications. The contents of the lecture will allow for a deeper understanding of modern computer-assisted drug design methods and how they are linked to experimental applications. The main focus is on computational medicinal chemistry, so that participants will be able to use relevant computer-based methods in own research projects. | ||||
| Literatur | Schneider, G. and Baringhaus, K.-H. (2008) Molecular Design - Concepts and Applications. Wiley-VCH, Weinheim, New York. Additional selected literature will be provided during the lecture. | ||||
| Voraussetzungen / Besonderes | The lecture is mandatory for all participants of the course "Computer-Assisted Drug Design" (535-0023-00 P). | ||||
| 535-0900-00L | Seminars on Drug Discovery and Development | 1 KP | 1K | R. Schibli, K.‑H. Altmann, M. Detmar, K. Eyer, C. Halin Winter, J. Hall, J.‑C. Leroux, U. Quitterer, G. Schneider, H. U. Zeilhofer | |
| Kurzbeschreibung | Vermittlung neuer Erkenntnisse im Bereich Arzneimittelfindung und -entwicklung anhand von Expertenvorträgen aus dem Hochschul- und Industriebereich. | ||||
| Lernziel | Einblick in aktuelle Forschungsgebiete im Gesamtbereich der Pharmazie. Vermittlung neuer Erkenntnisse im Bereich Arzneimittelfindung und -entwicklung. | ||||
| Inhalt | Seminarreihe des Instituts für Pharmazeutische Wissenschaften. Expertinnen und Experten aus Akademia und Industrie berichten über neue Erkenntnisse. | ||||
| 535-2000-00L | Seminar for Group Members Findet dieses Semester nicht statt. | 0 KP | 2S | G. Schneider | |
| Kurzbeschreibung | Weekly group seminar, in which members of the research team present and discuss the results of their projects and selected reports from the current scientific literature. | ||||
| Lernziel | Participants learn to present scientific studies and discuss own results in greater context. | ||||