Jeffrey W. Bode: Catalogue data in Spring Semester 2022

Name Prof. Dr. Jeffrey W. Bode
FieldSynthetic Organic Chemistry
Lab. für Organische Chemie
ETH Zürich, HCI F 315
Vladimir-Prelog-Weg 1-5/10
8093 Zürich
Telephone+41 44 633 21 03
DepartmentChemistry and Applied Biosciences
RelationshipFull Professor

529-0074-00LBCB IV: Analytical Biochemistry and Biophysics
Only for students of Biochemistry - Chemical Biology
5 credits7PB. Rubi, J. W. Bode, R. Glockshuber, E. C. Meister
AbstractPractical Introduction to Experimental Methods in Analytical and Bioanalytical Chemistry
ObjectiveTo acquire a sound knowledge of the instrumentation and methods for the analysis of molecules, including organic compounds and biological molecules.

To learnabout the most important practical techniques in analytical chemistry.

To write critical reports for each experiment and analytical technique.
ContentThe course will comprise of maximum 10 experiments from the following themes: Spectroscopic structural characterisation, analytical characterisation, Bio-physical characterisation. Experiments that will be part of this curriculum are: Circular dichroism (CD) spectroscopy, UV spectroscopy, Mass Spectromety, Nuclear Magnetic Resonance, HPLC and Size exclusion separations, Isothermal titration calorimetry as well as a number of other bio-physical and biological characterisation techniques.
Lecture notesLearning Materials will be made available on an online platform (web page or Moodle)
LiteratureLearning Materials will be made available on an online platform (web page or Moodle)
Prerequisites / NoticePrerequisites / Notice 529-0011-04 "Allgemeine Chemie (Praktikum)"
529-0051-00 "Analytische Chemie" I (3. Semester)
529-0058-00 "Analytische Chemie II" (4. Semester) enrolment in parallel to the lab class, or completed in an earlier semester.
551-0128-00L Fundamentals of Biology I

BCB Students should also be enrolled in "Instumentalanalyse organischer Verbindungen".
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Media and Digital Technologiesassessed
Project Managementfostered
Social CompetenciesCommunicationassessed
Cooperation and Teamworkassessed
Customer Orientationfostered
Leadership and Responsibilityfostered
Self-presentation and Social Influence fostered
Sensitivity to Diversityfostered
Personal CompetenciesAdaptability and Flexibilityfostered
Creative Thinkingfostered
Critical Thinkingassessed
Integrity and Work Ethicsassessed
Self-awareness and Self-reflection assessed
Self-direction and Self-management assessed
529-0222-00LOrganic Chemistry II3 credits2V + 1UB. Morandi, J. W. Bode
AbstractThis course builds on the material learned in Organic Chemistry I or Organic Chemistry II for Biology/Pharmacy Students. Topics include advanced concepts and mechanisms of organic reactions and introductions to pericyclic and organometallic reactions. The basics or retro- and forward synthesis are also introduced.
ObjectiveGoals of this course include a deeper understanding of basic organic reactions and mechanisms as well as advanced transformations. Reactive intermediates including carbenes and nitrenes are covered, along with methods for their generation and use in complex molecule synthesis. Frontier molecular orbital theory (FMO) is introduced and used to rationalize pericyclic reactions including Diels Alder reactions, cycloadditions, and rearrangements (Cope, Claisen). The basic concepts and key reactions of catalytic organometallic chemistry, which are key methods in modern organic synthesis, are introduced, with an emphasis on their catalytic cycles and elementary steps. All of these topics are combined in an overview of strategies for complex molecule synthesis, with specific examples from natural product derived molecules used as medicines.
ContentRedox neutral reactions and rearrangements, advanced transformations of functional groups and reaction mechanisms, carbenes and nitrenes, frontier molecular orbital theory (FMO), cycloadditions and pericyclic reactions, introduction to organometallic chemistry and catalytic cross couplings, protecting groups, retrosynthetic analysis of complex organic molecules, planning and execution of multi-step reactions.
Lecture notesThe lecture notes and additional documents including problem sets are available as PDF files online, without charge. Link:
LiteratureClayden, Greeves, and Warren. Organic Chemistry, 2nd Edition. Oxford University Press, 2012.
529-0290-00LOrganic Chemistry (Seminar) Restricted registration - show details 0 credits2SJ. W. Bode, E. M. Carreira, H. Wennemers, R. Zenobi
AbstractSeminars on Current Topics in Organic Chemistry, Chemical Biology, and Analytical Chemistry.
ObjectiveAwareness of contemporary trends in science.
529-0299-00LOrganic Chemistry0 credits1.5KJ. W. Bode, E. M. Carreira, P. Chen, H. Wennemers, R. Zenobi
AbstractUpdates on Research and Contemporary Literature in Organic Chemistry and Chemical Biology.
ObjectiveProblem solving in organic chemistry and chemical biology.