Jeffrey W. Bode: Katalogdaten im Frühjahrssemester 2022
|Herr Prof. Dr. Jeffrey W. Bode
|Synthetische Organische Chemie
Lab. für Organische Chemie
ETH Zürich, HCI F 315
|+41 44 633 21 03
|Chemie und Angewandte Biowissenschaften
|BCB IV: Analytische Biochemie und Biophysik
Nur für Studierende des Studiengangs Biochemie- Chemische Biologie
|B. Rubi, J. W. Bode, R. Glockshuber, E. C. Meister
|Organic Chemistry II
|2V + 1U
|B. Morandi, J. W. Bode
|This course builds on the material learned in Organic Chemistry I or Organic Chemistry II for Biology/Pharmacy Students. Topics include advanced concepts and mechanisms of organic reactions and introductions to pericyclic and organometallic reactions. The basics or retro- and forward synthesis are also introduced.
|Goals of this course include a deeper understanding of basic organic reactions and mechanisms as well as advanced transformations. Reactive intermediates including carbenes and nitrenes are covered, along with methods for their generation and use in complex molecule synthesis. Frontier molecular orbital theory (FMO) is introduced and used to rationalize pericyclic reactions including Diels Alder reactions, cycloadditions, and rearrangements (Cope, Claisen). The basic concepts and key reactions of catalytic organometallic chemistry, which are key methods in modern organic synthesis, are introduced, with an emphasis on their catalytic cycles and elementary steps. All of these topics are combined in an overview of strategies for complex molecule synthesis, with specific examples from natural product derived molecules used as medicines.
|Redox neutral reactions and rearrangements, advanced transformations of functional groups and reaction mechanisms, carbenes and nitrenes, frontier molecular orbital theory (FMO), cycloadditions and pericyclic reactions, introduction to organometallic chemistry and catalytic cross couplings, protecting groups, retrosynthetic analysis of complex organic molecules, planning and execution of multi-step reactions.
|The lecture notes and additional documents including problem sets are available as PDF files online, without charge. Link: https://morandi.ethz.ch/education.html
|Clayden, Greeves, and Warren. Organic Chemistry, 2nd Edition. Oxford University Press, 2012.
|Organic Chemistry (Seminar)
|J. W. Bode, E. M. Carreira, H. Wennemers, R. Zenobi
|Seminars on Current Topics in Organic Chemistry, Chemical Biology, and Analytical Chemistry.
|Awareness of contemporary trends in science.
|J. W. Bode, E. M. Carreira, P. Chen, H. Wennemers, R. Zenobi
|Updates on Research and Contemporary Literature in Organic Chemistry and Chemical Biology.
|Problem solving in organic chemistry and chemical biology.