Jeffrey W. Bode: Catalogue data in Autumn Semester 2017

Name Prof. Dr. Jeffrey W. Bode
FieldSynthetic Organic Chemistry
Address
Lab. für Organische Chemie
ETH Zürich, HCI F 315
Vladimir-Prelog-Weg 1-5/10
8093 Zürich
SWITZERLAND
Telephone+41 44 633 21 03
E-mailbode@org.chem.ethz.ch
DepartmentChemistry and Applied Biosciences
RelationshipFull Professor

NumberTitleECTSHoursLecturers
529-0221-00LOrganic Chemistry I3 credits2V + 1UE. M. Carreira, J. W. Bode
AbstractChemical reactivity and classes of compounds. Eliminations, fragmentations, chemistry of aldehydes and ketones (hydrates, acetals, imines, enamines, nucleophilic addition of organometallic compounds, reactions with phosphorus and sulfur ylides; reactions of enolates as nucleophiles) and of carboxylic acid derivatives. Aldol reactions.
ObjectiveAcquisition of a basic repertoire of synthetic methods including important reactions of aldehydes, ketones, carboxylic acids and carboxylic acid derivatives, as well as eliminations and fragmentations. Particular emphasis is placed on the understanding of reaction mechanisms and the correlation between structure and reactivity. A deeper understanding of the concepts presented during the lecture is reached by solving the problems handed out each time and discussed one week later in the exercise class.
ContentChemical reactivity and classes of compounds. Eliminations, fragmentations, chemistry of aldehydes and ketones (hydrates, acetals, imines, enamines, nucleophilic addition of organometallic compounds, reactions with phosphorus and sulfur ylides; reactions of enolates as nucleophiles) and of carboxylic acid derivatives. Aldol reactions.
Lecture notesA pdf file of the printed lecture notes is provided online. Supplementary material may be provided online.
LiteratureNo set textbooks. Optional literature will be proposed at the beginning of the class and in the lecture notes.
529-0241-00LAdvanced Methods and Strategies in Synthesis7 credits3GJ. W. Bode
AbstractAdvanced Modern Methods and Strategies in Synthesis
ObjectiveKnowledge of modern methods in asymmetric stereocontrol, enantioselective catalysis, and organic reaction mechanisms.
ContentCurrent trends in methods for and approaches to synthesis of complex natural products, pharmaceuticals, and biological molecules; fragment coupling and protecting group strategies; chemical ligation and biomolecules synthesis; enantioselective catalysis including ligand design and optimization; cross coupling reactions from preactivated precursors; C-H activation and oxidation chemistry; building block synthesis with chiral auxiliaries and reagents; new concepts in asymmetric catalysis. Analysis of key primarily literature including identification of trends, key precendents, and emerging topics will be emphasized.
Lecture noteswill be provided in class and online
LiteratureSuggesting Textbooks
1. Walsh and Kozlowski, Fundamentals of Asymmetric Catalysis, 1st Ed., University Science Books, 2009.
2. Anslyn and Dougherty, Modern Physical Organic Chemistry, 1st Ed., University Science Books, 2006.
529-0290-00LOrganic Chemistry (Seminar) Restricted registration - show details 0 credits2SE. M. Carreira, J. W. Bode, P. S. Dittrich, D. Hilvert, H. Wennemers, R. Zenobi
Abstract
Objective
529-0299-00LOrganic Chemistry0 credits1.5KJ. W. Bode, E. M. Carreira, P. Chen, P. S. Dittrich, D. Hilvert, H. Wennemers, R. Zenobi
Abstract
Objective