Jeffrey W. Bode: Catalogue data in Autumn Semester 2017 |
Name | Prof. Dr. Jeffrey W. Bode |
Field | Synthetic Organic Chemistry |
Address | Lab. für Organische Chemie ETH Zürich, HCI F 315 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND |
Telephone | +41 44 633 21 03 |
bode@org.chem.ethz.ch | |
Department | Chemistry and Applied Biosciences |
Relationship | Full Professor |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
529-0221-00L | Organic Chemistry I | 3 credits | 2V + 1U | E. M. Carreira, J. W. Bode | |
Abstract | Chemical reactivity and classes of compounds. Eliminations, fragmentations, chemistry of aldehydes and ketones (hydrates, acetals, imines, enamines, nucleophilic addition of organometallic compounds, reactions with phosphorus and sulfur ylides; reactions of enolates as nucleophiles) and of carboxylic acid derivatives. Aldol reactions. | ||||
Objective | Acquisition of a basic repertoire of synthetic methods including important reactions of aldehydes, ketones, carboxylic acids and carboxylic acid derivatives, as well as eliminations and fragmentations. Particular emphasis is placed on the understanding of reaction mechanisms and the correlation between structure and reactivity. A deeper understanding of the concepts presented during the lecture is reached by solving the problems handed out each time and discussed one week later in the exercise class. | ||||
Content | Chemical reactivity and classes of compounds. Eliminations, fragmentations, chemistry of aldehydes and ketones (hydrates, acetals, imines, enamines, nucleophilic addition of organometallic compounds, reactions with phosphorus and sulfur ylides; reactions of enolates as nucleophiles) and of carboxylic acid derivatives. Aldol reactions. | ||||
Lecture notes | A pdf file of the printed lecture notes is provided online. Supplementary material may be provided online. | ||||
Literature | No set textbooks. Optional literature will be proposed at the beginning of the class and in the lecture notes. | ||||
529-0241-00L | Advanced Methods and Strategies in Synthesis | 7 credits | 3G | J. W. Bode | |
Abstract | Advanced Modern Methods and Strategies in Synthesis | ||||
Objective | Knowledge of modern methods in asymmetric stereocontrol, enantioselective catalysis, and organic reaction mechanisms. | ||||
Content | Current trends in methods for and approaches to synthesis of complex natural products, pharmaceuticals, and biological molecules; fragment coupling and protecting group strategies; chemical ligation and biomolecules synthesis; enantioselective catalysis including ligand design and optimization; cross coupling reactions from preactivated precursors; C-H activation and oxidation chemistry; building block synthesis with chiral auxiliaries and reagents; new concepts in asymmetric catalysis. Analysis of key primarily literature including identification of trends, key precendents, and emerging topics will be emphasized. | ||||
Lecture notes | will be provided in class and online | ||||
Literature | Suggesting Textbooks 1. Walsh and Kozlowski, Fundamentals of Asymmetric Catalysis, 1st Ed., University Science Books, 2009. 2. Anslyn and Dougherty, Modern Physical Organic Chemistry, 1st Ed., University Science Books, 2006. | ||||
529-0290-00L | Organic Chemistry (Seminar) | 0 credits | 2S | E. M. Carreira, J. W. Bode, P. S. Dittrich, D. Hilvert, H. Wennemers, R. Zenobi | |
Abstract | |||||
Objective | |||||
529-0299-00L | Organic Chemistry | 0 credits | 1.5K | J. W. Bode, E. M. Carreira, P. Chen, P. S. Dittrich, D. Hilvert, H. Wennemers, R. Zenobi | |
Abstract | |||||
Objective |