Jan Kisielow: Katalogdaten im Herbstsemester 2016 |
| Name | Herr Dr. Jan Kisielow |
| Adresse | Inst. f. Molecular Health Sciences ETH Zürich, HPL G 14.2 Otto-Stern-Weg 7 8093 Zürich SWITZERLAND |
| jan.kisielow@biol.ethz.ch | |
| Departement | Umweltsystemwissenschaften |
| Beziehung | Dozent |
| Nummer | Titel | ECTS | Umfang | Dozierende | |
|---|---|---|---|---|---|
| 551-0223-00L | Immunology III  | 4 KP | 2V | M. Kopf, M. Bachmann, J. Kisielow, A. Lanzavecchia, S. R. Leibundgut, A. Oxenius, R. Spörri | |
| Kurzbeschreibung | Diese Vorlesung liefert einen detaillierten Einblick in die - Entwicklung von T Zellen und B Zellen - Dynamik einer Immunantwort bei akuten und chronischen Infektionen - Mechanismen von Immunpathologie - neue Impfstoffstrategien | ||||
| Lernziel | Sie verstehen - die Entwicklung, Aktivierung, und Differenzierung verschiedener Typen von T Zellen und deren Effektormechanismen während einer Immunantwort - die Erkennung von pathogenen Mikroorganismen und molekulare Ereignisse nach Infektion einer Zelle - Ereignisse und Signale für die Reifung von naiven B Zellen zu antikörperproduzierenden Plasmazellen und Gedächtniszellen, - Optimierung von B Zellantworten durch das intelligente Design neuer Impfstoffe | ||||
| Inhalt | o Development and selection of CD4 and CD8 T cells, natural killer T cells (NKT), and regulatory T cells (Treg) o NK T cells and responses to lipid antigens o Differentiation, characterization, and function of CD4 T cell subsets such as Th1, Th2, and Th17 o Overview of cytokines and their effector function o Co-stimulation (signals 1-3) o Dendritic cells o Evolution of the "Danger" concept o Cells expressing Pattern Recognition Receptors and their downstream signals o T cell function and dysfunction in acute and chronic viral infections | ||||
| Literatur | Unterlagen zur Vorlesung sind erhältlich bei: https://moodle-app2.let.ethz.ch/course/view.php?id=2581¬ifyeditingon=1 | ||||
| Voraussetzungen / Besonderes | Immunology I and II recommended but not compulsory | ||||
| 551-1171-00L | Immunology: from Milestones to Current Topics | 4 KP | 2S | B. Ludewig, J. Kisielow, M. Kopf, A. Oxenius, Uni-Dozierende | |
| Kurzbeschreibung | Milestones in Immunology: on old concepts and modern experiments | ||||
| Lernziel | The course will cover six grand topics in immunology (B cells, innate immunity, antigen presentation, tumor immunity, thymus and T cells, cytotoxic T cells and NK cells) and for each grand topic four hours will be allocated. During the first double hour, historical milestone papers will be presented by the supervisor providing an overview on the development of the conceptional framework and critical technological advances. The students will also prepare themselves for this double lecture by reading the historical milestone papers and contributing to the discussion. In the following lecture up to four students will present each a recent high impact research paper which emerged from the landmark achievements of the previously discussed milestone concepts. | ||||
| Inhalt | Milestones and current topics of innate immunity, antigen presentatino, B cells, thymus and T cells, cytotoxic T cells and NK cells, and tumor immunology. | ||||
| Skript | Original and review articles will be distributed by the lecturer. | ||||
| Literatur | Literaturunterlagen werden vor Beginn des Kurses auf folgender website zugänglich sein: Moodle Course https://moodle-app2.let.ethz.ch/course/view.php?id=1002 | ||||