Gunnar Jeschke: Catalogue data in Spring Semester 2018

Name Prof. Dr. Gunnar Jeschke
FieldElectron Paramagnetic Resonance
Inst. Mol. Phys. Wiss.
ETH Zürich, HCI F 227
Vladimir-Prelog-Weg 1-5/10
8093 Zürich
Telephone+41 44 632 57 02
DepartmentChemistry and Applied Biosciences
RelationshipFull Professor

529-0499-00LPhysical Chemistry1 credit1KB. H. Meier, M. Ernst, P. H. Hünenberger, G. Jeschke, F. Merkt, M. Reiher, J. Richardson, R. Riek, S. Riniker, T. Schmidt, R. Signorell, H. J. Wörner
AbstractSeminar series covering current developments in Physical Chemistry
551-1414-00LMolecular and Structural Biology V: Studying Macromolecules by NMR and EPR4 credits2VF. Allain, A. D. Gossert, G. Jeschke, K. Wüthrich
AbstractThe course provides an overview of experimental methods for the determination of structures of macromolecules at atomic resolution in solution. The two main methods used are Nuclear Magnetic Resonance (NMR) spectroscopy and Electron Paramagnetic Resonance (EPR) spectroscopy.
ObjectiveInsight into the methodology, areas of application and limitations of these two methods for the structure determination of biological macromolecules. Practical exercises with spectra to have hands on understanding of the methodology.
ContentPart I: Methods for the determination of protein structures in solution using nuclear magnetic resonance (NMR) spectroscopy. Experimental approaches to the characterization of intramolecular dynamics of proteins.
Part II: NMR methods for structurally characterizing RNA and protein-RNA complexes.
Part III: EPR of biomolecules
Literature1) Wüthrich, K. NMR of Proteins and Nucleic Acids, Wiley-Interscience.
2) Dominguez et al, Prog Nucl Magn Reson Spectrosc. 2011 Feb;58(1-2):1-61.
3) Duss O et al, Methods Enzymol. 2015;558:279-331.