Gunnar Jeschke: Catalogue data in Spring Semester 2018

Name	Prof. Dr. Gunnar Jeschke
Field	Electron Paramagnetic Resonance
Address	Inst. Mol. Phys. Wiss. ETH Zürich, HCI F 227 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND
Telephone	+41 44 632 57 02
E-mail	gunnar.jeschke@phys.chem.ethz.ch
Department	Chemistry and Applied Biosciences
Relationship	Full Professor

Number	Title	ECTS	Hours	Lecturers
529-0499-00L	Physical Chemistry	1 credit	1K	B. H. Meier, M. Ernst, P. H. Hünenberger, G. Jeschke, F. Merkt, M. Reiher, J. Richardson, R. Riek, S. Riniker, T. Schmidt, R. Signorell, H. J. Wörner
Abstract	Seminar series covering current developments in Physical Chemistry
Learning objective
551-1414-00L	Molecular and Structural Biology V: Studying Macromolecules by NMR and EPR	4 credits	2V	F. Allain, A. D. Gossert, G. Jeschke, K. Wüthrich
Abstract	The course provides an overview of experimental methods for the determination of structures of macromolecules at atomic resolution in solution. The two main methods used are Nuclear Magnetic Resonance (NMR) spectroscopy and Electron Paramagnetic Resonance (EPR) spectroscopy.
Learning objective	Insight into the methodology, areas of application and limitations of these two methods for the structure determination of biological macromolecules. Practical exercises with spectra to have hands on understanding of the methodology.
Content	Part I: Methods for the determination of protein structures in solution using nuclear magnetic resonance (NMR) spectroscopy. Experimental approaches to the characterization of intramolecular dynamics of proteins. Part II: NMR methods for structurally characterizing RNA and protein-RNA complexes. Part III: EPR of biomolecules
Literature	1) Wüthrich, K. NMR of Proteins and Nucleic Acids, Wiley-Interscience. 2) Dominguez et al, Prog Nucl Magn Reson Spectrosc. 2011 Feb;58(1-2):1-61. 3) Duss O et al, Methods Enzymol. 2015;558:279-331.