Jonathan Hall: Catalogue data in Spring Semester 2022

Name	Prof. Dr. Jonathan Hall
Field	Pharmazeutische Chemie
Address	Inst. f. Pharmazeutische Wiss. ETH Zürich, HCI H 437 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND
Telephone	+41 44 633 74 35
Fax	+41 44 633 13 69
E-mail	jonathan.hall@pharma.ethz.ch
Department	Chemistry and Applied Biosciences
Relationship	Full Professor

Number	Title	ECTS	Hours	Lecturers
535-0002-00L	Introduction to Pharmaceutical Sciences II	2 credits	2V	J. Hall, A. Burden, S. Erni, K. Eyer, C. Halin Winter, S.‑D. Krämer, E. Kut Bacs, C. Müller, C. Steuer
Abstract	First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities.
Learning objective	First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities.
Content	Introduction to Pharmaceutical Sciences by selected milestones of research and development. Overview on research activities at the Institute of Pharmaceutical Sciences, which is focused on drug delivery and development (from concepts to prototypes). Sensitization for communication skills and information management. Demonstration of job opportunities in community pharmacies, in the hospital, in industry, and in the public sector by experts in the different fields.
Lecture notes	Handouts for individual lectures.
Prerequisites / Notice	Interactive teaching Prerequisites: Einführung in die Pharmazeutischen Wissenschaften I
535-0231-00L	Medicinal Chemistry II	2 credits	2V	J. Hall
Abstract	The lectures give an overview of selected drugs and the molecular mechanisms underlying their therapeutic effects in disease. The historical and modern-day methods by which these drugs were discovered and developed are described. Structure-function relationships and the biophysical rules underlying ligand-target interactions will be discussed and illustrated with examples.
Learning objective	Basic understanding of therapeutic agents with respect to molecular, pharmacological and pharmaceutical properties.
Content	Molecular mechanisms of action of drugs. Structure function and biophysical basis of ligand-target interactions.
Lecture notes	Will be provided electronically in parts before each individual lecture.
Literature	- G.L. Patrick, "An Introduction to Medicinal Chemistry", 5th edition, Oxford University Press (2013) - D. Steinhilber, M. Schubert-Zsilavecz, H.J. Roth, "Medizinische Chemie", Deutscher Apotheker Verlag Stuttgart (2005) - J.H. Block, J.M. Beale, "Organic Medicinal and Pharmaceutical Chemistry", 11th edition, Lippincott, Williams, Wilkins (2002) - A. Gringauz, "How Drugs Act and Why", Wiley (1997) - R. Silverman and M. Holladay, "The Organic Chemistry of Drug Design and Drug Action" 3rd Edition, Academic Press, (2014)
Prerequisites / Notice	Requirements: Knowledge of physical and organic chemistry, biochemistry and biology; Medicinal Chemistry I.
535-0900-00L	Seminars on Drug Discovery and Development	1 credit	1K	R. Schibli, K.‑H. Altmann, C. Halin Winter, J. Hall, J.‑C. Leroux, U. Quitterer, G. Schneider, H. U. Zeilhofer
Abstract	State-of-the-art information on drug discovery and development by experts from academia and industry.
Learning objective	State-of-the-art information on drug discovery and development.
Content	Seminar series of the Institute of Pharmaceutical Sciences. Experts from academia and industry report on relevant topics.