Matthias Gstaiger: Catalogue data in Spring Semester 2022 |
| Name | Dr. Matthias Gstaiger |
| Address | Inst. f. Molekulare Systembiologie ETH Zürich, HPM F 43 Otto-Stern-Weg 3 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 34 49 |
| matthias.gstaiger@imsb.biol.ethz.ch | |
| Department | Biology |
| Relationship | Lecturer |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 551-0128-00L | Fundamentals of Biology I  Registrations via myStudies until 28.1.2022 at the latest. Subsequent registrations will not be considered. | 8 credits | 8P | M. Gstaiger, A. Cléry, E. Dultz, C. H. Giese, R. Kroschewski, M. Künzler | |
| Abstract | This 1st year Laboratory course introduces the students to the basic experimental techniques used in the classical and modern molecular biosciences. In the first year (Praktikum GL BioI) the students will be introduced into the basic concepts and methods of Microbiology, Biochemistry and Molecular Biology in 12 consecutive course days. | ||||
| Learning objective | Introduction to the biology of unicellular organisms and practical experience with biochemical and molecular biology techniques. General Praktikum-information and course material can be obtained from Moodle The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail). | ||||
| Content | This 1st year Laboratory course introduces the students to the entire range of classical and modern molecular biosciences. Students will participate in 12 consecutive course days. The practical will operate in two shifts on Thursday and Friday. morning shift 8:00-13:00 afternoon shift 13:30-18:30 Program Day 1: Handling and detection of microorganisms Day 2: Morphological, biochemical and genetic differentiation of microorganisms Day 3: Biotic interactions and genetics of bacteria Day 4: Metabolism and physiology of bacteria Day 5: DNA extraction, tranformation (E.coli, yeast) Day 6: RNA extraction, Life cycle of eukaryotic cells Day 7: Purification of TAQ polymerase from E coli by ionexchange chromatography Day 8: Characterizing fractions of the purification of TAQ polymerase (SDS-PAGE, WB) Day 9: mRNA splicing in yeast by RT-PCR and purified TAQ polymerase Day 10: Affinity chromatography, protein crystallization and structure Day 11: Protein folding, protein stability and Enzyme kinetics Day 12: Protein folding, protein stability and Enzyme kinetics | ||||
| Lecture notes | Laboratory manuals can be downloaded from Moodle | ||||
| Prerequisites / Notice | PLEASE NOTE THE FOLLOWING RULES Your attendance is obligatory and you have to attend all 12 Praktikum days of GL BioI. Absences are only acceptable if you are able to provide a Doctor’s certificate. The original Dr's certificate has to be given to Dr. M. Gstaiger (HPM F43) within five days of the absence of the Praktikum day. If there will be any exceptional or important situations then you should directly contact the Director of Studies of D-Biol, who will decide if you are allowed to miss a Praktikum day or not. HIGHLY IMPORTANT!! 1. Due to the increased number of students, the official Praktikum registration has to be done, using myStudies, preferably at the end of HS21 but not later than January 28, 2022. 2. Later registration is NOT possible and can NOT be accepted! 3. The course registration for FS2022 is usually possible at the end of fall semester 2021 and you will obtain an E-mail from the Rectorate when the course registration using myStudies is possible. The 12 course days of the Praktikum Grundlagen Biologie-I will take place Thursday or Friday during the spring semester 2022. Therefore, you have to make sure already now that you will not have any other activities / commitments during these days. The exact course schedule will be communicated before the beginning of the spring semester. PRAKTIKUM DAYS FS22 (Thursdays): 24.02.; 03.03.; 10.03.; 17.03.; 24.03.; 31.03.; 07.04.; 28.04.; 5.05.; 12.05.; 19.05.; 02.06. PRAKTIKUM DAYS FS22 (Fridays): 25.02.; 04.03.; 11.03.; 18.03.; 25.03.; 1.04.; 8.04.; 29.04.; 06.05.; 13.05.; 20.05.; 03.06. No Praktikum during the Easter vacation: 11.04-22.04. | ||||
| 551-0130-00L | Fundamentals of Biology II  Registrations via myStudies until 2.2.2022 at the latest. Subsequent registrations will not be considered. | 8 credits | 8P | M. Gstaiger, N. Aceto, J. A. Antunes Pereira, M. Cangkrama, H. Gehart, Z. Kontarakis, W. Kovacs, A. Leitner, S. L. Masneuf, P. Picotti, U. Sauer, E. B. Truernit, A. Wutz, N. Zamboni | |
| Abstract | This introductory Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. In the second year (Praktikum GL Bio II) the students will perform three praktikum days in: - Plant Biology - Animal Models - Genomics - Molecular Systems Biology (total of 12 experiments) Each experiment takes one full day. | ||||
| Learning objective | Introduction to theoretical and experimental biology General Praktikum-information and course material: Moodle The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail). | ||||
| Content | The class is divided into four blocks: Cell Biology, Plant Biology, Genomics AND Molecular Systems Biology. One block lasts three weeks. Animal Models: - Tissue structure and biology - Mouse anatomy and histology - Tissue repair and cancer GENOMICS: - Chromosome preparations from mammalian cells - Genome Editing - Cancer genomics Molecular Systems Biology: - Preparation of proteomics and metabolomics samples - Analysis of proteomics and metabolomics data - Interpretation of proteomics and metabolomics data PLANT BIOLOGY: - Plants and light - Phytohormones and other growth factors - Molecular biology of systemic gene silencing | ||||
| Lecture notes | Laboratory manuals All scripts and additional course information is available on Moodle. | ||||
| Prerequisites / Notice | THE PRAKTIKUM RULES: Your attendance is obligatory and you have to attend all 12 Praktikum days. Absences are only acceptable if you are able to provide a Doctor’s certificate. The original Dr's certificate has to be given to Dr. M. Gstaiger (HPM F43) within five days of the absence of the Praktikum day. If there will be any exceptional or important situations then you should directly contact the Director of Studies of D-Biol, who will decide if you are allowed to miss a Praktikum day or not. HIGHLY IMPORTANT!! 1. Due to the increased number of students, the official Praktikum registration has to be done, using myStudies, preferably at the end of HS21 but not later than 2.2.2022. 2. Later registration is NOT possible and can NOT be accepted! 3. The course registration for FS22 is usually possible at the end of HS21 and you will obtain an E-mail from the Rectorate when the course registration using myStudies is possible. Students can register for a practice group via myStudies. As soon as the course unit is registered in myStudies, a text box appears indicating that a group can be selected. Accordingly, students can select a group in the next step. If more than 180 students register, the surplus students will be placed on a waiting list and then allocated by the course responsible. The Praktikum GL BioII FS22 will take place during the following days and therefore, you have to make sure already now that you do not have any other activities & commitments during these days: PRAKTIKUM DAYS DURING FS22 (Monday): 21.02.; 28.02.; 07.03.; 14.03.; 21.03.; 28.03.; 04.04.; 11.04.; 02.05.; 09.05.; 16.05.; 23.05.; No Praktikum during the Easter break: 18.04-29.04. | ||||
| 551-0130-01L | Fundamentals of Biology II Registrations via myStudies until 2.2.2022 at the latest. Subsequent registrations will not be considered. | 4 credits | 3P | M. Gstaiger, J. A. Antunes Pereira, S. L. Masneuf, E. B. Truernit | |
| Abstract | This introductory Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. In the second year (Praktikum GL Bio II) the students will perform three praktikum days in: - Animal Models - Plant Biology (total of 6 experiments) Each experiment takes one full day. | ||||
| Learning objective | Introduction to theoretical and experimental biology General Praktikum-information and course material: Moodle The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail). | ||||
| Content | The class is divided into two blocks: Animal Models and Plant Biology. One block lasts three weeks. ANIMAL MODELS: - Tissue structure and biology - Mouse anatomy and histology - Tissue repair and cancer PLANT BIOLOGY: - Phytohormones and other growth factors - Molecular biology of systemic gene silencing - Transport and storage - Literature reading and presentation | ||||
| Lecture notes | Laboratory manuals All scripts and additional course information is available on Moodle. | ||||
| Prerequisites / Notice | THE PRAKTIKUM RULES: Your attendance is obligatory and you have to attend all 6 Praktikum days. Absences are only acceptable if you are able to provide a Doctor’s certificate. The original Dr's certificate has to be given to Dr. M. Gstaiger (HPM F43) within five days of the absence of the Praktikum day. If there will be any exceptional or important situations then you should directly contact the Director of Studies of D-Biol, who will decide if you are allowed to miss a Praktikum day or not. HIGHLY IMPORTANT!! 1. Due to the increased number of students, the official Praktikum registration has to be done, using myStudies, preferably at the end of HS21 but not later than 2.2.2022. 2. Later registration is NOT possible and can NOT be accepted! 3. The course registration for FS22 is usually possible at the end of HS21 and you will obtain an E-mail from the Rectorate when the course registration using myStudies is possible. Students can register for a practice group via myStudies. As soon as the course unit is registered in myStudies, a text box appears indicating that a group can be selected. Accordingly, students can select a group in the next step. If more than 180 students register, the surplus students will be placed on a waiting list and then allocated by the course responsible. The Praktikum GL BioII FS22 will take place during the following days and therefore, you have to make sure already now that you do not have any other activities & commitments during these days: PRAKTIKUM DAYS DURING FS22 (Monday): 21.02.; 28.02.; 07.03.; 14.03.; 21.03.; 28.03.; 04.04.; 11.04.; 02.05.; 09.05.; 16.05.; 23.05.; No Praktikum during the Easter break: 18.04-29.04. | ||||
| 551-0364-00L | Functional Genomics Information for UZH students: Enrolment to this course unit only possible at ETH. No enrolment to module BIO 254 at UZH. Please mind the ETH enrolment deadlines for UZH students: Link | 3 credits | 2V | C. von Mering, B. Bodenmiller, M. Gstaiger, H. Rehrauer, R. Schlapbach, K. Shimizu, N. Zamboni, further lecturers | |
| Abstract | Functional genomics is key to understanding the dynamic aspects of genome function and regulation. Functional genomics approaches use the wealth of data produced by large-scale DNA sequencing, gene expression profiling, proteomics and metabolomics. Today functional genomics is becoming increasingly important for the generation and interpretation of quantitative biological data. | ||||
| Learning objective | Functional genomics is key to understanding the dynamic aspects of genome function and regulation. Functional genomics approaches use the wealth of data produced by large-scale DNA sequencing, gene expression profiling, proteomics and metabolomics. Today functional genomics is becoming increasingly important for the generation and interpretation of quantitative biological data. Such data provide the basis for systems biology efforts to elucidate the structure, dynamics and regulation of cellular networks. | ||||
| Content | The curriculum of the Functional Genomics course emphasizes an in depth understanding of new technology platforms for modern genomics and advanced genetics, including the application of functional genomics approaches such as advanced sequencing, proteomics, metabolomics, clustering and classification. Students will learn quality controls and standards (benchmarking) that apply to the generation of quantitative data and will be able to analyze and interpret these data. The training obtained in the Functional Genomics course will be immediately applicable to experimental research and design of systems biology projects. | ||||
| Prerequisites / Notice | The Functional Genomics course will be taught in English. | ||||