Matthias Gstaiger: Catalogue data in Spring Semester 2018
|Name||Dr. Matthias Gstaiger|
Inst. f. Molekulare Systembiologie
ETH Zürich, HPM F 43
|Telephone||+41 44 633 34 49|
|551-0102-01L||Fundamentals of Biology I |
Registrations via myStudies until 31.1.2018 at the latest. Subsequent registrations will not be considered.
|6 credits||8P||P. Kallio, M. Künzler, T. A. Beyer, M. Gstaiger, M. Kopf, R. Kroschewski, D. Ramseier, M. Stoffel, E. B. Truernit, A. Wutz, further lecturers|
|Abstract||This 1st year Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. During this course (Praktikum GL BioI) the students will do three praktikum days in:|
- Cell Biology I
- Plant Anantomy & Ecology
(total of 12 experiments)
Each experiment takes one full day.
|Objective||Introduction to theoretical and experimental biology|
General Praktikum-information and course material can be obtained from Moodle
The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail).
|Content||The class is divided into four blocks: Biochemistry, Microbiology, Plant biology & Ecology and Cell Biology I.|
- TAQ Analysis (part 1): Protein purification
- TAQ Analysis (part 2): SDS-Gelelektrophoresis
- TAQ Analysis (part 3): Activity test of the purified protein
Day 1: Basics for the work with microorganisms & Isolation of microorganisms from the environment
Day 2: Morphology and diagnostics of bacteria & Antimicrobial agents
Day 3: Morphology of fungi & Microbial physiology and interactions
PLANT BIOLOGY & ECOLOGY
- Microscopy and plant cell anatomy
- Plant organ anatomy and gene expression
CELL BIOLOGY I:
- Anatomy of mouse & Blood cell determination
- Chromosome preparation and analysis
|Lecture notes||Laboratory manuals|
- The protocols can be downloaded from: Moodle
- The protocols can be found from: Moodle
- You HAVE TO print the pdf-file, which is also used as the lab manual during the experiments. Therefore, you have to have the Script always with you, when doing the experiments in Microbiology.
PLANT BIOLOGY & ECOLOGY:
- The protocols can be found from: Moodle
CELL BIOLOGY I:
- The handouts of the experiments entitled "Histology" will be provided
- The protocols of "Anatomy of mouse & Blood cell determination" and "Chromosome preparation and analysis" can be found from: Moodle
|Prerequisites / Notice||PLEASE NOTE THE FOLLOWING RULES|
Your attendance is obligatory and you have to attend all 12 Praktikum days of GL BioI. Absences are only acceptable if you are able to provide a Doctor’s certificate. The original Dr's certificate has to be given to PD Dr. P. Kallio (HCI F413) within five days of the absence of the Praktikum day.
If there will be any exceptional or important situations then you should directly contact the Director of Studies of D-Biol, who will decide if you are allowed to miss a Praktikum day or not.
1. Due to the increased number of students, the official Praktikum registration has to be done, using myStudies, preferably at the end of HS17 but not later than Sunday January 31, 2018.
2. Later registration is NOT possible and can NOT be accepted!
3. The course registration for FS2018 is usually possible at the end of Autumn semester 2017 and you will obtain an E-mail from the Rectorate when the course registration using myStudies is possible.
Extra Praktikum days have to be organized if more than 220 - 240 students will attend the Praktikum. The group division is random and the reserved Extra Praktikum days are:
- May 31, 2018
- June 4 - 5, 2018
The Praktikum GL BioI will take place during the following days and therefore, you have to make sure already now that you will not have any other activities / commitments during these days:
PRAKTIKUM DAYS FS18 (Thursdays):
Eastern & Spring vacation: 30.3 - 8.4.2018
EXTRA PRAKTIKUM DAYS (if necessary)
|551-0224-00L||Advanced Proteomics |
For master students from the 2nd semester on, also doctoral candidates and post docs.
|4 credits||6G||R. Aebersold, L. Gillet, M. Gstaiger, A. Leitner, P. Pedrioli|
|Abstract||Goal of the course is to analyze current and newly emerging technologies and approaches in protein and proteome analysis with regard to their application in biology, biotechnology and medicine.|
Format: Introduction by instructor followed by discussions stimulated by reading assignments and exercises.
|Objective||To discuss current and newly emerging technologies and approaches in protein and proteome analysis with regard to their applications in biology, biotechnology, medicine and systems biology.|
|Content||Block course teaching current methods for the acquisition and processing of proteomic datasets.|
|Prerequisites / Notice||Number of people: Not exceeding 30.|
Students from ETHZ, Uni Zurich and University of Basel
Non-ETH students must register at ETH Zurich as special students http://www.rektorat.ethz.ch/students/admission/auditors/index_EN
|551-0362-00L||Analysis of Signaling Networks by Mass Spectrometry |
Number of participants limited to 10.
The enrolment is done by the D-BIOL study administration.
|6 credits||7G||M. Gstaiger, M. Claassen, B. Wollscheid|
|Abstract||This course provides the theoretical and practical basis for the biochemical and computational analysis of signaling networks using quantitative mass spectrometry and advanced statistical methods.|
|Objective||In this course we will introduce basic and emerging techniques to study dynamic signalling networks using state of the art quantitative mass spectrometry techniques. This will involve the systematic characterization of signaling networks by affinity purification and phospho-peptide enrichment combined with quantitative mass spectrometry. We will also introduce and apply computational tools for statistical analysis, data visualization and network inference to build new hypothesis on the basis of the obtained data.|
|Prerequisites / Notice||This course requires a basic knowledge in mass spectrometry based proteomics and experience in computational data processing using R or MatLab. Ideally this course should be combined with course 551-0352-00L "Protein Analysis by Mass Spectrometry".|
Information for UZH students:
Enrolment to this course unit only possible at ETH. No enrolment to module BIO 254 at UZH.
Please mind the ETH enrolment deadlines for UZH students: Link
|3 credits||2V||C. von Mering, C. Beyer, B. Bodenmiller, M. Gstaiger, H. Rehrauer, R. Schlapbach, K. Shimizu, N. Zamboni, further lecturers|
|Abstract||Functional genomics is key to understanding the dynamic aspects of genome function and regulation. Functional genomics approaches use the wealth of data produced by large-scale DNA sequencing, gene expression profiling, proteomics and metabolomics. Today functional genomics is becoming increasingly important for the generation and interpretation of quantitative biological data.|
|Objective||Functional genomics is key to understanding the dynamic aspects of genome function and regulation. Functional genomics approaches use the wealth of data produced by large-scale DNA sequencing, gene expression profiling, proteomics and metabolomics. Today functional genomics is becoming increasingly important for the generation and interpretation of quantitative biological data. Such data provide the basis for systems biology efforts to elucidate the structure, dynamics and regulation of cellular networks.|
|Content||The curriculum of the Functional Genomics course emphasizes an in depth understanding of new technology platforms for modern genomics and advanced genetics, including the application of functional genomics approaches such as advanced microarrays, proteomics, metabolomics, clustering and classification. Students will learn quality controls and standards (benchmarking) that apply to the generation of quantitative data and will be able to analyze and interpret these data. The training obtained in the Functional Genomics course will be immediately applicable to experimental research and design of systems biology projects.|
|Prerequisites / Notice||The Functional Genomics course will be taught in English.|
|551-1310-00L||A Problem-Based Approach to Cellular Biochemistry |
Number of participants limited to 15.
|6 credits||2G||M. Peter, E. Dultz, M. Gstaiger, V. Korkhov, B. Kornmann, V. Panse, A. E. Smith|
|Abstract||Independent, guided acquisition of an overview over a defined area of research, identification of important open questions, development of an experimental strategy to address a defined question, and formulation of this strategy within the framework of a research grant.|
|Objective||The students will learn to acquire independently an overview over a defined area of research, and to identify important open questions. In addition, they will learn to develop an experimental strategy to address a defined question, and to formulate this strategy within the framework of a research grant.|
|Content||The students will work in groups of two to three, in close contact with a tutor (ETH Prof or senior scientist). The overview and the small research grant will be developed independently by the students, with guidance from the tutor through regular mandatory meetings. The students will write both the overview and the grant in short reports, and present them to their colleagues.|
|Literature||The identification of appropriate literature is a component of the course.|
|Prerequisites / Notice||This course will be taught in english, and requires extensive independent work.|