Renato Paro: Catalogue data in Spring Semester 2018 |
| Name | Prof. em. Dr. Renato Paro |
| Field | Biosysteme |
| Address | Professur für Biophysik ETH Zürich, BSS H 41 Klingelbergstrasse 48 4056 Basel SWITZERLAND |
| renato.paro@bsse.ethz.ch | |
| Department | Biosystems Science and Engineering |
| Relationship | Professor emeritus |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 551-0140-00L | Epigenetics | 4 credits | 2V | R. Paro, U. Grossniklaus, R. Santoro, A. Wutz | |
| Abstract | Epigenetics studies the inheritance of traits that cannot be attributed to changes in the DNA sequence. The lecture will present an overview of different epigenetic phenomena and provide detailed insight into the underlying molecular mechanisms. The role of epigenetic processes in the development of cancer and other disorders will be discussed. | ||||
| Learning objective | The aim of the course is to gain an understanding of epigenetic mechanisms and their impact on the development of organisms, regenerative processes or manifestation of disease. | ||||
| Content | Topics - historical overview, concepts and comparison Genetics vs. Epigenetics - Biology of chromatin: structure and function, organization in the nucleus and the role of histone modifications in processes like transcription and replication - DNA methylation as an epigenetic modification - Inheritance of epigenetic modifications during cell division: cellular memory - Stability and reversibility of epigenetic modifications: cellular plasticity and stem cells - Genomic imprinting in plants and mammals - X chromosome inactivation and dosis compensation - position effects, paramutations and transvection - RNA-induced gene silencing - The role of epigenetic processes in cancer development or cell aging | ||||
| 636-0301-00L | Current Topics in Biosystems Science and Engineering | 2 credits | 1S | T. Stadler, N. Beerenwinkel, Y. Benenson, K. M. Borgwardt, P. S. Dittrich, M. Fussenegger, A. Hierlemann, D. Iber, M. H. Khammash, D. J. Müller, S. Panke, R. Paro, R. Platt, S. Reddy, T. Schroeder, J. Stelling | |
| Abstract | This seminar will feature invited lectures about recent advances and developments in systems biology, including topics from biology, bioengineering, and computational biology. | ||||
| Learning objective | To provide an overview of current systems biology research. | ||||
| Content | The final list of topics will be available at http://www.bsse.ethz.ch/education/. | ||||
| 636-1005-AAL | Bio V: Bioinformatics Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 5 credits | 7R | R. Paro | |
| Abstract | |||||
| Learning objective | |||||
| Literature | Pevsner, Bioinformatics and Functional Genomics, chapters: 1 – 7 | ||||
| 636-1010-AAL | Bio Lab V: Molecular Biology III Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 1 credit | 3R | R. Paro | |
| Abstract | |||||
| Learning objective | |||||
| Content | “-omics” analyses in eukaryotic cells (sample preparation for and analysis of omics data) | ||||