Markus Stoffel: Catalogue data in Autumn Semester 2017 |
| Name | Prof. Dr. Markus Stoffel |
| Field | Metabolic Diseases |
| Address | Inst. f. Molecular Health Sciences ETH Zürich, HPL H 36 Otto-Stern-Weg 7 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 45 60 |
| Fax | +41 44 633 13 62 |
| stoffel@biol.ethz.ch | |
| Department | Biology |
| Relationship | Full Professor |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 551-0016-AAL | Biology II  Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 2 credits | 4R | M. Stoffel, E. Hafen | |
| Abstract | The lecture course Biology II is a basic introductory course into biology for students who need to pass this course for admission to their MSc curriculum. | ||||
| Learning objective | The objective of the lecture course Biology II is the understanding of form, function, and development of animals and of the basic underlying mechanisms. | ||||
| Content | The following numbers of chapters refer to the text-book "Biology" (Campbell & Reece, 7th edition, 2005) on which the course is based. Chapters 1-4 are a basic prerequisite. The sections "Structure of the Cell" (Chapters 5-10, 12, 17) and "General Genetics" (Chapters 13-16, 18, 46) are covered by the lecture Biology I. 1. Genomes, DNA Technology, Genetic Basis of Development Chapter 19: Eukaryotic Genomes: Organization, Regulation, and Evolution Chapter 20: DNA Technology and Genomics Chapter 21: The Genetic Basis of Development 2. Form, Function, and Development of Animals I Chapter 40: Basic Principles of Animal Form and Function Chapter 41: Animal Nutrition Chapter 44: Osmoregulation and Excretion Chapter 47: Animal Development 3. Form, Function, and Develeopment of Animals II Chapter 42: Circulation and Gas Exchange Chapter 43: The Immune System Chapter 45: Hormones and the Endocrine System Chapter 48: Nervous Systems Chapter 49: Sensory and Motor Mechanisms | ||||
| Literature | The following text-book is the basis for the courses Biology I and II: „Biology“, Campbell and Reece, 7th Edition, 2005, Pearson/Benjamin Cummings, ISBN 0-8053-7166-4 | ||||
| Prerequisites / Notice | Prerequisite: Lecture course Biology I of winter semester | ||||
| 551-0309-00L | Concepts in Modern Genetics | 6 credits | 4V | Y. Barral, D. Bopp, A. Hajnal, M. Stoffel, O. Voinnet | |
| Abstract | Concepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | ||||
| Learning objective | This course focuses on the concepts of classical and modern genetics and genomics. | ||||
| Content | The topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | ||||
| Lecture notes | Scripts and additional material will be provided during the semester. | ||||
| 551-1409-00L | RNA Biology Lecture Series II: Non-coding RNAs: Biology and Therapeutics | 4 credits | 2V | J. Hall, M. Stoffel, further lecturers | |
| Abstract | This course covers aspects of RNA biology related to the functions of non-coding RNAs as well as their use as drugs to treat diseases. | ||||
| Learning objective | The students should get familiar with the wide array of roles, which non-coding RNAs play in cellular functions. | ||||
| Content | Micro RNAs; computational approaches to miRNAs; micro RNA function in metabolism; viruses and viral RNAs; nucleic acid-based drugs; ncRNA-mediated genome regulation; epigenetic programming of genome remodelling in ciliates; telomerase and telomeres; tRNA biology. http://www.nccr-rna-and-disease.ch/tiki-index.php?page=LectureSeries | ||||
| Prerequisites / Notice | Basic knowledge of cell and molecular biology. | ||||
| 551-1515-00L | Insulin Signaling  Number of participants limited to 12. The enrolment is done by the D-BIOL study administration. | 6 credits | 7G | M. Stoffel | |
| Abstract | Introduction to the physiological and biochemical action of insulin signaling and its role in the fasted/feeding response and in obesity and diabetes. | ||||
| Learning objective | The students will obtain an overview about the current topics of research in insulin signaling and how it impacts on growth, metabolism and cell differentiation. They will learn to design experiments and use techniques necessary to analyze different aspects of insulin signaling,including physiological actions in whole animals as well as in tissue culture. Through lectures and literature seminars, they will learn about the open questions of insulin signaling research and discuss approaches to address these questions experimentally. In practical lab projects the students will perform physiological in vivo studies as well as biochemical experiments. Finally, they will learn how to present and discuss their data. Student assessment is a graded semester performance based on individual performance in the laboratory, a written exam and the lab data presentation. | ||||