Julia Vorholt-Zambelli: Catalogue data in Autumn Semester 2019

Name Prof. Dr. Julia Vorholt-Zambelli
FieldMikrobiologie
Address
Institut für Mikrobiologie
ETH Zürich, HCI F 429
Vladimir-Prelog-Weg 1-5/10
8093 Zürich
SWITZERLAND
Telephone+41 44 632 55 24
Fax+41 44 633 13 07
E-mailjvorholt@ethz.ch
DepartmentBiology
RelationshipFull Professor

NumberTitleECTSHoursLecturers
551-0110-AALFundamentals of Biology II: Microbiology
Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement.

Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit.
2 credits2RJ. Vorholt-Zambelli
AbstractStructure, function, genetics of prokaryotic microorganisms and fungi.
ObjectiveBasic principles of cell structure, growth physiology, energy metabolism, gene expression. Biodiversity of Bacteria and Archaea in the carbon, nitrogen, and sulfur cycles in nature. Phylogeny and evolution. Pathogenicity. Biotechnology. Antibiotics.
ContentBasic principles of cell structure, growth physiology, energy metabolism, gene expression. Biodiversity of Bacteria and Archaea in the carbon, nitrogen, and sulfur cycles in nature. Phylogeny and evolution. Pathogenicity. Biotechnology. Antibiotics.
Lecture notesnone
LiteratureBrock, Biology of Microorganisms (Madigan, M.T. and Martinko, J.M., eds.), 12th ed., Pearson Prentice Hall, 2009
Prerequisites / Noticenone
551-0205-00LChallenges in Plant Sciences Information
Number of participants limited to 40.
2 credits2KS. C. Zeeman, M. Paschke, A. Rodriguez-Villalon, C. Schöb, J. Vorholt-Zambelli, A. Widmer, further lecturers
AbstractThe colloquium introduces students to the disciplines in plant sciences and provides integrated knowledge from the molecular level to ecosystems and from basic research to applications, making use of the synergies between the different research groups of the PSC. The colloquium offers a unique chance to approach interdisciplinary topics as a challenge in the field of plant sciences.
ObjectiveMajor objectives of the colloquium are:

introduction of graduate students and Master students to the broad field of plant sciences
promotion of an interdisciplinary and integrative teaching program
promotion of active participation and independent work of students
promotion of presentation and discussion skills
increased interaction among students and professors
ContentChallenges in Plant Sciences will cover the following topics:
Chemical communication among plants, insect and pathogens.
Specificity in hormone signaling.
Genetic networks.
Plant-plant interactions.
Resilience of tropical ecosystems.
Regulatory factors controlling cell wall formation.
Chlorophyll breakdown.
Innate immunity.
Disease resistance genes.
Sustainable agroecosystems.
551-1103-00LMicrobial Biochemistry4 credits2VJ. Vorholt-Zambelli, J. Piel
AbstractThe lecture course aims at providing an advanced understanding of the physiology and metabolism of microorganisms. Emphasis is on processes that are specific to bacteria and archaea and that contribute to the widespread occurrence of prokaryotes. Applied aspects of microbial biochemistry will be pointed out as well as research fields of current scientific interest.
ObjectiveThe lecture course aims at providing an advanced understanding of the physiology and metabolism of microorganisms.
ContentImportant biochemical processes specific to bacteria and archaea will be presented that contribute to the widespread occurrence of prokaryotes. Applied aspects of microbial biochemistry will be pointed out as well as research fields of current scientific interest. Emphasis is on concepts of energy generation and assimilation.

List of topics:
Microbial Biochemistry and origin of life
Methanogenesis and methylotrophy
Anaerobic oxidation of methane
Microbial autotrophy
Complex: (Ligno-)Cellulose and in demand for bioenergy
Challenging: Aromatics and hydrocarbons
Living on a diet and the anaplerotic provocation
20 amino acids: the making of
Extending the genetic code
The 21st and 22nd amino acid
Some exotic biochemistry: nucleotides, cofactors
Ancient biochemistry? Iron-sulfur clusters, polymers
Secondary metabolites: playground of evolution
Lecture notesA script will be provided during the course.
551-1106-00LProgress Reports in Microbiology and Immunology
Students must sign up via secr.micro.biol.ethz.ch
0 credits5SJ. Piel, M. Aebi, H.‑M. Fischer, W.‑D. Hardt, A. Oxenius, J. Vorholt-Zambelli
AbstractPresentation and discussion of current research results in the field of Microbiology and Infection Immunology
ObjectivePrecise and transparent presentation of research findings in relation to the current literature, critical discussion of experimental data and their interpretation, development and presentation of future research aims
551-1109-00LSeminars in Microbiology0 credits2KM. Aebi, H.‑M. Fischer, W.‑D. Hardt, M. Künzler, J. Piel, S. Sunagawa, J. Vorholt-Zambelli
AbstractSeminars by invited speakers covering selected microbiology themes.
ObjectiveDiscussion of selected microbiology themes presented by invited speakers.
551-1129-00LUnderstanding and Engineering Microbial Metabolism Restricted registration - show details
Number of participants limited to 6.

The enrolment is done by the D-BIOL study administration.
6 credits7PJ. Vorholt-Zambelli
AbstractThis laboratory course has a focus on current research topics in our laboratory related to metabolic engineering, the general understanding of metabolism, and is focused particularly on C1-metabolism. Projects will be conducted in small groups.
ObjectiveThe course aims at introducing key principles of metabolic engineering and techniques applied in metabolism related research. The main focus of this block course is on practical work and will familiarize participants with complementary approaches, in particular genetic, biochemical and analytical techniques. Results will be presented by students in scientific presentations.
ContentThe course and will include topics such as pathway elucidation & engineering and related ongoing research projects in the lab. Experimental work applied during the course will comprise methods such as cloning work & transformation, growth determination, enzyme activity assays, liquid-chromatography mass-spectrometry and dynamic labeling experiments.
Lecture notesNone
LiteratureWill be provided at the beginning of the course.
752-4001-00LMicrobiology2 credits2VM. Ackermann, M. Schuppler, J. Vorholt-Zambelli
AbstractTeaching of basic knowledge in microbiology with main focus on Microbial Cell Structure and Function, Molecular Genetics, Microbial Growth, Metabolic Diversity, Phylogeny and Taxonomy, Prokaryotic Diversity, Human-Microbe Interactions, Biotechnology.
ObjectiveTeaching of basic knowledge in microbiology.
ContentDer Schwerpunkt liegt auf den Themen: Bakterielle Zellbiologie, Molekulare Genetik, Wachstumsphysiologie, Biochemische Diversität, Phylogenie und Taxonomie, Prokaryotische Vielfalt, Interaktion zwischen Menschen und Mikroorganismen sowie Biotechnologie.
Lecture notesWird von den jeweiligen Dozenten ausgegeben.
LiteratureDie Behandlung der Themen erfolgt auf der Basis des Lehrbuchs Brock, Biology of Microorganisms