Christian Frei: Katalogdaten im Herbstsemester 2021 |
| Name | Herr Dr. Christian Frei |
| Adresse | Inst. f. Biomedizinische Technik ETH Zürich, GLC F 12.2 Gloriastrasse 37/ 39 8092 Zürich SWITZERLAND |
| Telefon | +41 44 632 45 85 |
| frei@biomed.ee.ethz.ch | |
| Departement | Informationstechnologie und Elektrotechnik |
| Beziehung | Dozent |
| Nummer | Titel | ECTS | Umfang | Dozierende | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 227-0945-00L | Cell and Molecular Biology for Engineers I This course is part I of a two-semester course. | 3 KP | 2G | C. Frei | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | The course gives an introduction into cellular and molecular biology, specifically for students with a background in engineering. The focus will be on the basic organization of eukaryotic cells, molecular mechanisms and cellular functions. Textbook knowledge will be combined with results from recent research and technological innovations in biology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | After completing this course, engineering students will be able to apply their previous training in the quantitative and physical sciences to modern biology. Students will also learn the principles how biological models are established, and how these models can be tested. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Lectures will include the following topics (part I and II): DNA, chromosomes, genome engineering, RNA, proteins, genetics, synthetic biology, gene expression, membrane structure and function, vesicular traffic, cellular communication, energy conversion, cytoskeleton, cell cycle, cellular growth, apoptosis, autophagy, cancer and stem cells. In addition, 4 journal clubs will be held, where recent publications will be discussed (2 journal clubs in part I and 2 journal clubs in part II). For each journal club, students (alone or in groups of up to three students) have to write a summary and discussion of the publication. These written documents will be graded and count as 40% for the final grade. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Scripts of all lectures will be available. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | "Molecular Biology of the Cell" (6th edition) by Alberts, Johnson, Lewis, Raff, Roberts, and Walter. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Kompetenzen |
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| 227-0949-00L | Biological Methods for Engineers (Basic Lab)  Number of participants limited to 10. | 3 KP | 5P | C. Frei | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | The course during 7 afternoons (13h to 18h) covers basic laboratory skills and safety, cell culture, protein analysis, RNA/DNA Isolation and RT-PCR. Each topic will be introduced, followed by practical work at the bench. Presence during the course is mandatory. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | The goal of this laboratory course is to give students practical exposure to basic techniques of cell and molecular biology. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | Enrollment is limited and students from the Master's programme in Biomedical Engineering (BME) have priority. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kompetenzen |
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| 752-0100-AAL | Biochemistry Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben. Alle andere Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen. | 2 KP | 4R | C. Frei | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Grundlegende Kenntnisse der Enzymologie, insbesondere die Struktur, Kinetik und Chemie von enzymkatalysierten Reaktionen in vitro und in vivo. Stoffwechselbiochemie: Absolvierende sind in der Lage, wesentliche zelluläre Stoffwechselvorgänge zu beschreiben und zu verstehen. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Based on the biology and chemistry courses in the 1. and 2. semester more detailed biochemical knowledge about enzymology, membrane biochemistry, and central metabolism will be presented | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Program Introduction, basics, composition of cells, biochemical units, repetition of relevant organic chemistry Structure and function of proteins Carbohydrates, structure of DNA Lipids an biological membranes Enzymes and enzyme kinetics Catalytic strategies Metabolism: Basic concepts and design. Repetition of basic thermodynamics Glycolysis The citric acid cycle Oxidative phosphorylation Fatty acid metabolism | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Principles of Biochemistry (5th Edition) 5th Edition by Laurence A. Moran (Author), Robert A Horton (Author), Gray Scrimgeour (Author), Marc Perry (Author) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literatur | Principles of Biochemistry (5th Edition) 5th Edition by Laurence A. Moran (Author), Robert A Horton (Author), Gray Scrimgeour (Author), Marc Perry (Author) | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | Basic knowledge in biology and chemistry is a precondition. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kompetenzen |
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| 752-0100-00L | Biochemie | 2 KP | 2V | C. Frei | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kurzbeschreibung | Grundlegende Kenntnisse der Enzymologie, insbesondere die Struktur, Kinetik und Chemie von enzymkatalysierten Reaktionen in vitro und in vivo. Stoffwechselbiochemie: Absolvierende sind in der Lage, wesentliche zelluläre Stoffwechselvorgänge zu beschreiben und zu verstehen. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lernziel | Studierende verstehen - die Struktur und Funktion von biologischen Makromolekülen - die kinetischen Grundlagen von enzymatischen Reaktionen - thermodynamische und mechanistische Grundlagen relevanter Stoffwechselprozesse Die Studierenden sind in der Lage, relevante Stoffwechselreaktionen detailliert zu beschreiben. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Inhalt | Kursinhalt Einführung, Grundlagen, Zusammensetzung der Zelle, biochemische Einheiten, Repetition relevanter Reaktionen der organischen Chemie Struktur und Funktion der Proteine Kohlenhydrate Lipide und biologische Membranen Enzyme und Enzymkinetik Katalytische Strategien Der Stoffwechsel: Konzepte, Grundmuster und thermodynamische Grundlagen Glykolyse und Gärung Citratzyklus Oxidative Phosphorylierung, Repetition der relevanten Grundlagen der Redoxchemie Fettsäuremetabolismus | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Skript | Als Skript dient: Horton et al. Biochemie (Pearson Verlag). | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Voraussetzungen / Besonderes | Vorausgesetzt werden Basiskenntnisse in Biologie und Chemie. | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Kompetenzen |
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