Michael Arand: Catalogue data in Autumn Semester 2017

Award: The Golden Owl
Name Prof. Dr. Michael Arand
(Professor Universität Zürich (UZH))
E-mailarandm@ethz.ch
DepartmentChemistry and Applied Biosciences
RelationshipLecturer

NumberTitleECTSHoursLecturers
529-0745-00LGeneral and Environmental Toxicology7 credits3VM. Arand, K. Hungerbühler, H. Nägeli, B. B. Stieger, I. Werner
AbstractToxicokinetic and toxicodynamic aspects of xenobiotic interactions with cellular structures and mechanisms. Toxic responses at the level of organs (immune-, neuro-, reproductive and genotoxicity) and organisms. Introduction into developmental toxicology and ecotoxicology.
ObjectiveUnderstanding of the impact of chemicals on biological systems; evaluation of the effects from different biomedical perspectives.
ContentExplanation of important interactions between xeniobiotic chemicals and cellular structures such as membranes, enzymes, and nucleic acids. Relevance of intake, distribution, excretion, and biochemical transformation processes. Relevance of mixtures. Explanation of important modes of toxic action such as immuno toxicity, neurotoxicity, reproduction toxicity, genotoxicity based on examples of certain xenobiotics and their effects on important organs.
Lecture notesCourse material will be handed out as the lectures progress
LiteratureTextbooks of pharmacology and toxicology (cf. list in course material)
Prerequisites / NoticeEducational basis: basic chemistry, biology and biochemistry