Rudolf Aebersold: Katalogdaten im Frühjahrssemester 2019 |
| Name | Herr Prof. Dr. Rudolf Aebersold |
| Lehrgebiet | Systembiologie |
| aebersold@imsb.biol.ethz.ch | |
| Departement | Biologie |
| Beziehung | Professor emeritus |
| Nummer | Titel | ECTS | Umfang | Dozierende | |
|---|---|---|---|---|---|
| 551-0002-00L | Allgemeine Biologie II  | 4 KP | 4G | U. Sauer, R. Aebersold, W. Gruissem | |
| Kurzbeschreibung | Grundlagen der Biochemie (Makromoleküle, Membranen, Zellstrukturen, Stoffwechsel) Molekulargenetik (Genexpression und Regulation, vom Gen zum Protein) Physiologie höherer Pflanzen (Struktur, Wachstum, Entwicklung, Nährstoffe, Transport und Reproduktion) | ||||
| Lernziel | Verständnis grundlegender Konzepte molekularer Biologie und Physiologie. | ||||
| Inhalt | Zellluläre Funktionen auf der Ebenen von Molekülen und Strukturen. Molekulare Vorgänge in der Prozessierung vom Gen zum Protein. Pflanzenphysiologie. Die folgenden Campbell Kapitel werden behandelt: Woche 1-5: Prof. Sauer 5 Biological macromolecules and lipids 7 Cell structure and function 8 Cell membranes 10 Respiration: introduction to metabolism 10 Cell respiration 11 Photosynthetic processes Woche 6-9: Prof. Aebersold 16 Nucleic acids and inheritance 17 Expression of genes 18 Control of gene expression 19 DNA Technology Woche 9-13: Prof. Gruissem 35 Plant Structure and Growth 36 Transport in vascular plants 37 Plant nutrition 38 Reproduction of flowering plants 39 Plants signal and behavior | ||||
| Skript | Kein Skript | ||||
| Literatur | Campbell, Reece et al: "Biologie" (10th global edition); Pearson 2015. | ||||
| 551-0003-AAL | General Biology I+II Belegung ist NUR erlaubt für MSc Studierende, die diese Lerneinheit als Auflagenfach verfügt haben. Alle andere Studierenden (u.a. auch Mobilitätsstudierende, Doktorierende) können diese Lerneinheit NICHT belegen. | 7 KP | 13R | U. Sauer, R. Aebersold, W. Gruissem, O. Y. Martin, A. Widmer | |
| Kurzbeschreibung | General Biology I: Organismic biology to teach the basic principles of classical and molecular genetics, evolutionary biology and phylogeny. General Biology II: Molecular biology approach to teach the basic principles of biochemistry, cell biology, cgenetics, evolutionary biology and form and function of vacular plants. | ||||
| Lernziel | General Biology I: The understanding of basic principles of biology (inheritance, evolution and phylogeny) and an overview of the diversity of life. General Biology II: The understanding basic concepts of biology: the hierarchy of the structural levels of biological organisation, with particular emphasis on the cell and its molecular functions, the fundamentals of metabolism and molecular genetics, as well as form and function of vascular plants. | ||||
| Inhalt | General Biology I: General Biology I focuses on the organismal biology aspects of genetics, evolution and diversity of life in the Campbell chapters 12-34. Week 1-7 by Alex Widmer, Chapters 12-25 12 Cell biology Mitosis 13 Genetics Sexual life cycles and meiosis 14 Genetics Mendelian genetics 15 Genetics Linkage and chromosomes 20 Genetics Evolution of genomes 21 Evolution How evolution works 22 Evolution Phylogentic reconstructions 23 Evolution Microevolution 24 Evolution Species and speciation 25 Evolution Macroevolution Week 8-14 by Oliver Martin, Chapters 26-34 26 Diversity of Life Introdution to viruses 27 Diversity of Life Prokaryotes 28 Diversity of Life Origin & evolution of eukaryotes 29 Diversity of Life Nonvascular&seedless vascular plants 30 Diversity of Life Seed plants 31 Diversity of Life Introduction to fungi 32 Diversity of Life Overview of animal diversity 33 Diversity of Life Introduction to invertebrates 34 Diversity of Life Origin & evolution of vertebrates General Biology II: The structure and function of biomacromolecules; basics of metabolism; tour of the cell; membrane structure and function; basic energetics of cellular processes; respiration, photosynthesis; cell cycle, from gene to protein; structure and growth of vascular plants, resource acquisition and transport, soil and plant nutrition. Specifically the following Campbell chapters will be covered: 3 Biochemistry Chemistry of water 4 Biochemistry Carbon: the basis of molecular diversity 5 Biochemistry Biological macromolecules and lipids 7 Cell biology Cell structure and function 8 Cell biology Cell membranes 10 Cell biology Respiration: introduction to metabolism 10 Cell biology Cell respiration 11 Cell biology Photosynthetic processes 16 Genetics Nucleic acids and inheritance 17 Genetics Expression of genes 18 Genetics Control of gene expression 19 Genetics DNA Technology 35 Plant structure&function Plant Structure and Growth 36 Plant structure&function Transport in vascular plants 37 Plant structure&function Plant nutrition 38 Plant structure&function Reproduction of flowering plants 39 Plant structure&function Plants signal and behavior | ||||
| Skript | No script | ||||
| Literatur | Campbell et al. (2015) Biology - A Global Approach. 10th Edition (Global Edition) | ||||
| Voraussetzungen / Besonderes | Basic general and organic chemistry This is a virtual self-study lecture for non-German speakers of the "Allgemeine Biology I (551-0001-00L) and "Allgemeine Biology II (551-0002-00L) lectures. The exam will be written jointly with the participants of this lecture. | ||||
| 551-0224-00L | Advanced Proteomics Für Masterstudierende ab 2. Semester, Doktorierende und Postdoktorierende | 4 KP | 6G | R. Aebersold, L. Gillet, M. Gstaiger, A. Leitner, P. Pedrioli | |
| Kurzbeschreibung | Ziel dieses Kurses ist es, etablierte und neue Technologien der Protein- und Proteome-Analyse kennenzulernen in Bezug auf ihre Anwendung in Biologie, Biotechnologie und Medizin. Format: Einführung durch Dozent mit anschliessender Diskussion, unterstützt durch Literaturarbeit und Übungen. | ||||
| Lernziel | Im Kurs werden sowohl die bereits etablierten als auch die neuesten derzeit entstehenden Technologien und Methoden in der Protein- und Proteomanlayse diskutiert im Hinblick auf ihre Anwendung in der Biologie, Biotechnologie, Medizin und Systembiologie. | ||||
| Inhalt | Block course teaching current methods for the acquisition and processing of proteomic datasets. | ||||
| Voraussetzungen / Besonderes | Number of people: Not exceeding 30. Students from ETHZ, Uni Zurich and University of Basel Non-ETH students must register at ETH Zurich as special students http://www.rektorat.ethz.ch/students/admission/auditors/index_EN | ||||
| 551-0324-00L | Systems Biology  | 6 KP | 4V | R. Aebersold, B. Christen, M. Claassen, U. Sauer | |
| Kurzbeschreibung | Introduction to experimental and computational methods of systems biology. By using baker’s yeast as a thread through the series, we focus on global methods for analysis of and interference with biological functions. Illustrative applications to other organisms will highlight medical and biotechnological aspects. | ||||
| Lernziel | - obtain an overview of global analytical methods - obtain an overview of computational methods in systems biology - understand the concepts of systems biology | ||||
| Inhalt | Overview of global analytical methods (e.g. DNA arrays, proteomics, metabolomics, fluxes etc), global interference methods (siRNA, mutant libraries, synthetic lethality etc.) and imaging methods. Introduction to mass spectrometry and proteomics. Concepts of metabolism in microbes and higher cells. Systems biology of developmental processes. Concepts of mathematical modeling and applications of computational systems biology. | ||||
| Skript | no script | ||||
| Literatur | The course is not taught by a particular book, but some books are suggested for further reading: - Systems biology in Practice by Klipp, Herwig, Kowald, Wierling und Lehrach. Wiley-VCH 2005 | ||||