Kaspar Locher: Catalogue data in Autumn Semester 2016 |
Name | Prof. Dr. Kaspar Locher |
Field | Molecular Membrane Biology |
Address | Inst. f. Molekularbiol.u.Biophysik ETH Zürich, HPK G 11 Otto-Stern-Weg 5 8093 Zürich SWITZERLAND |
Telephone | +41 44 633 39 91 |
locher@mol.biol.ethz.ch | |
URL | http://www.locherlab.ethz.ch |
Department | Biology |
Relationship | Full Professor |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
551-0307-00L | Molecular and Structural Biology I: Protein Structure and Function D-BIOL BSc students are obliged to take part I and part II (next semester) as a two-semester course | 3 credits | 2V | R. Glockshuber, K. Locher, E. Weber-Ban | |
Abstract | Biophysics of protein folding, membrane proteins and biophysics of membranes, enzymatic catalysis, catalytic RNA and RNAi, current topics in protein biophysics and structural biology. | ||||
Objective | Understanding of structure-function relationships in proteins and in protein folding, detailed understanding of biophysics and physical methods as well as modern methods for protein purification and microanalytics. | ||||
Lecture notes | Scripts on the individual topics can be found under http://www.mol.biol.ethz.ch/teaching. | ||||
Literature | Basics: - Creighton, T.E., Proteins, Freeman, (1993) - Fersht, A., Enzyme, Structure and Mechanism in Protein Science (1999), Freeman. - Berg, Tymoczko, Stryer: Biochemistry (5th edition), Freeman (2001). Current topics: References will be given during the lectures. . | ||||
551-1323-AAL | Fundamentals of Biology II: Biochemistry and Molecular Biology Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 4 credits | 11R | K. Locher, N. Ban, R. Glockshuber, E. Weber-Ban | |
Abstract | The course provides an introduction to Biochemistry / Molecular Biology with some emphasis on chemical and biophysical aspects. | ||||
Objective | Topics include the structure-function relationship of proteins / nucleic acids, protein folding, enzymatic catalysis, cellular pathways involved in bioenergetics and the biosynthesis and breakdown of amino acids, glycans, nucleotides, fatty acids and phospholipids, and steroids. There will also be a discussion of DNA replication and repair, transcription, and translation. | ||||
Lecture notes | none | ||||
Literature | "Biochemistry", Berg/Tymoczko/Stryer, 8th edition, Palgrave Macmillan, International edition | ||||
551-1323-00L | Fundamentals of Biology II: Biochemistry and Molecular Biology | 4 credits | 4V | K. Locher, N. Ban, R. Glockshuber, E. Weber-Ban | |
Abstract | The course provides an introduction to Biochemistry / Molecular Biology with some emphasis on chemical and biophysical aspects. | ||||
Objective | Topics include the structure-function relationship of proteins / nucleic acids, protein folding, enzymatic catalysis, cellular pathways involved in bioenergetics and the biosynthesis and breakdown of amino acids, glycans, nucleotides, fatty acids and phospholipids, and steroids. There will also be a discussion of DNA replication and repair, transcription, and translation. | ||||
Lecture notes | none | ||||
Literature | mandatory: "Biochemistry", Autoren: Berg/Tymoczko/Stryer, 8th edition, Palgrave Macmillan, International edition (the English version will be preordered at the Polybuchhandlung) | ||||
Prerequisites / Notice | Some of the lectures are given in the English language. | ||||
551-1411-00L | Molecular and Structural Biology III: Current Topics The course will only take place with a minimum of 6 participants. | 2 credits | 1V | K. Locher, F. Allain, N. Ban, R. Glockshuber, M. Pilhofer, E. Weber-Ban | |
Abstract | The course discusses current topics and cutting edge research in the structural, molecular, and biochemical study of cellular macromolecules. Student participation is an essential component of the course and will contribute to the exam grade | ||||
Objective | The goal is to discuss cutting edge research in the structural, molecular, and biochemical study of cellular macromolecules. Students will also have an opportunity to present and discuss recent breakthroughs relevant to the research fields presented by the faculty teaching the course (see http://www.mol.biol.ethz.ch/research.html for details on the topics). | ||||
Literature | Will be distributed by the instructors | ||||
551-1619-00L | Structural Biology | 1 credit | 1K | R. Glockshuber, F. Allain, N. Ban, K. Locher, E. Weber-Ban, G. Wider, K. Wüthrich | |
Abstract | The course consists of a series of research seminars on Structural Biology, Biochemistry and Biophysics, given by both scientists of the National Center of Competence in Research (NCCR) in Structural Biology and external speakers. Information on the individual seminars is provided on the following websites: http://www.structuralbiology.uzh.ch/educ002.asp http://www.biol.ethz.ch/dbiol-cal/index | ||||
Objective | The goal of this course is to provide doctoral and postdoctoral students with a broad overview on the most recent developments in biochemistry, structural biology and biophysics. |