Wilhelm Krek: Catalogue data in Spring Semester 2015

Name Prof. Dr. Wilhelm Krek
FieldZellbiologie
DepartmentBiology
RelationshipFull Professor

NumberTitleECTSHoursLecturers
551-0104-00LFundamentals of Biology II Information Restricted registration - show details
Registrations via myStudies until Sunday 1.2.2015, at the latest. Subsequent registrations will not be considered.
8 credits8PP. Kallio, F. Caudron, J. Fütterer, W. Kovacs, W. Krek, M. Künzler, M. Meyer, H. Stocker, U. Suter, S. Werner, Professors
AbstractThis introductory Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. In the second year (Praktikum GL Bio II) the students will perform three experiments each in:
- Microbiology
- Plant Physiology
- Genetics and
- Cell Biology II.

(total of 12 experiments)

Each experiment takes one full day.
Learning objectiveIntroduction to theoretical and experimental biology

www-link for general Praktikum-information and course material: https://moodle-app2.let.ethz.ch/course/view.php?id=1152

The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail).
ContentThe class is divided into four blocks: Cell Biology II, Genetics, Microbiology and Plant Physiology. One block lasts three weeks.

CELL BIOLOGY II:
- Cells: Cell types & staining methods, cell fusion & cell motility,
- Tissue and development: histology of mice embryos & embryogenesis
- Repair mechanisms: DNA repair & wound healing,

GENETICS:
- Yeast genetics
- Drosophila genetics
- Human genetics

MICROBIOLOGY:
Day 1: Basics for the work with microorganisms & Isolation of microorganisms from the environment
Day 2: Morphologie und Diagnostik von Bakterien & Antimikrobielle Wirkstoffe
Day 3: Morphologie der Pilze & Mikrobielle Physiologie und Interaktionen

PLANT PHYSIOLOGY:
- Plants and light
- Phytohormones and other growth factors
- Molecular biology of systemic gene silencing
- Literature and presentations

The students will also prepare short presentations (approx. 10 min) of the various topics within this course.
Lecture notesLaboratory manuals

CELL BIOLOGY II
- The protocols can be downloaded from: https://moodle-app2.let.ethz.ch/course/view.php?id=1152

MICROBIOLOGY:
- The protocols can be found from: https://moodle-app2.let.ethz.ch/course/view.php?id=1152
- You HAVE TO print the pdf-file, which is also used as the lab manual during the experiments. Thus, you have to have the Script always with you, when doing the experiments in Microbiology.

PLANT PHYSIOLOGY
- The protocols can be found from: https://moodle-app2.let.ethz.ch/course/view.php?id=1152

GENETICS
- The protocols can be found from: https://moodle-app2.let.ethz.ch/course/view.php?id=1152
LiteratureProtocols for microbiology part of the lab course are provided in the lab manual
Prerequisites / NoticeTHE PRAKTIKUM RULES:

Your attendance is obligatory and you have to attend all 12 Praktikum days. Absences are only acceptable if you are able to provide a Doctor’s certificate. If there will be any exceptional or important situations then you should directly contact the Student Advisor of D-Biol, who will decide if you are allowed to miss a Praktikum day or not.


HIGHLY IMPORTANT!!

1. Due to the increased number of students, the official Praktikum registration has to be done, using myStudies, preferably at the end of HS14 but not later than Sunday February 1, 2015.

2. Later registration is NOT possible and can NOT be accepted!

3. The course registration for FS15 is usually possible at the end of HS14 and you will obtain an E-mail from the Rectorate when the course registration using myStudies is possible.

The Praktikum GL BioII FS15 will take place during the following days and therefore, you have to make sure already now that you do not have any other activities & commitments during these days:

- 20.2.2015
- 27.2
- 6.3
- 13.3
- 20.3
- 27.3

3.4 - 12.4.2015 Eastern and spring vacation

- 17.4
- 24.4
- 8.5
- 15.5
- 22.5
- 29.5
551-0106-00LFundamentals of Biology IB5 credits5GS. C. Zeeman, W. Krek, J. Levine, O. Y. Martin, G. Velicer, A. Wutz
AbstractThis course is an introduction into the basic principles of evolution, diversity, animal/plant form and function, and ecology.
Learning objectiveIntroduction into aspects of modern biology and fundamental biological concepts.
ContentThe course is divided into distinct chapters
1. Mechanisms of evolution.
2. The evolutionary history of biological diversity (bacteria and archea, protists, plants and animals).
3. Plant form and function (growth and development, nutrient and resource acquisition, reproduction and environmental responses).
4. Animal form and function (nutrition, immune system, hormones, reproduction, nervous system and behaviour).
5. Ecology (population ecology, community ecology, ecosystems and conservation ecology).
Lecture notesNo script
LiteratureThis course is based on the textbook 'Biology' (Campbell, Reece, 9th edition). The structure of the course follows that of the book. It is recommended to purchase the English version.
Prerequisites / NoticePart of the contents of the book need to be learned through independent study.
551-0326-00LCell Biology Information 6 credits4VS. Werner, U. Auf dem Keller, W. Kovacs, W. Krek, A. M. Kyburz Kooznetsoff, M. Schäfer, U. Suter
AbstractThis Course introduces principle concepts, techniques, and experimental strategies used in modern Cell Biology. Major topics include: neuron-glia interactions in health and disease; mitochondrial dynamics; RNA processing; growth factor action in development, tissue repair and disease; cell metabolism, in particular sensing and signaling mechanisms, cell organelles, and lipid metabolism.
Learning objective-To prepare the students for successful and efficient lab work by learning how to ask the right questions and to use the appropriate techniques in a research project.
-To convey knowledge about neuron-glia interactions in health and disease.
-To provide information on growth factor signaling in development, repair and disease and on the use of growth factors or their receptors as drug targets for major human diseases
-To convey knowledge on the mechanisms underlying repair of injured tissues
-To provide the students with an overview of mitochondrial dynamics.
-Providing an understanding of RNA processing reactions and their regulations.
-To provide a comprehensive understanding of metabolic sensing mechanisms occurring in different cell types and organelles in response to glucose, hormones, oxygen, nutrients as well as lipids, and to discuss downstream signaling pathways and cellular responses.
-To provide models explaining how disturbances in complex metabolic control networks and bioenergetics can lead to disease and to highlight latest experimental approaches to uncover the intricacies of metabolic control at the cellular and organismal level.
-Providing the background and context that foster cross-disciplinary scientific thinking.
551-1502-00LSystems Biology of Complex Disease: Medical Sciences Information 3 credits4SM. Stoffel, K.‑H. Altmann, W. Krek, W. Langhans, G. A. Spinas, C. Wolfrum
AbstractInsights into pathophysiological aspects of selected metabolic disorders in man. One focus will be on diabetes and/or obesity.
Learning objectiveThe goal of the course is to give a broad overview about important aspects of physiology, pathophysiology, clinical course and complications, pathology and underlying molecular mechanisms of selected metabolic disorders in man.
ContentThe block course comprises lectures, hands-on courses and journal clubs on molecular and clinical physiology, clinical chemistry, pathology and pharmacology.
Prerequisites / NoticeThis block course is facultative module of the PhD Program “Systems Biology of Complex Diseases” organized Competence Center for Systems Physiology and Metabolic Diseases.

The course is only open for PhD Students of the Life Science Zurich PhD Program (ETH Zurich and University Zurich). Preference will be given to Students from the Program “Systems Biology of Complex Diseases”. Preferably students have already taken the introductory course of the PhD Program on “Systems Biology”.

Number of people: Max. 25

Registration by E-mail to
Davina Rodgers
davina.rodgers@cell.biol.ethz.ch
ETH Zürich
CC-SPMD Competence Center for
Systems Physiology and Metabolic Diseases
Institute of Cell Biology
Schafmattstr. 18, HPM F 22
CH-8093 Zürich

+41 44 633 33 51 (phone)
+41 44 633 13 57 (fax)