Sven Panke: Catalogue data in Autumn Semester 2020
|Name||Prof. Dr. Sven Panke|
ETH Zürich, BSS G 43.3
|Telephone||+41 61 387 32 09|
|Department||Biosystems Science and Engineering|
|636-0102-00L||Advanced Bioengineering||4 credits||3S||S. Panke, Y. Benenson, P. S. Dittrich, M. Fussenegger, A. Hierlemann, M. H. Khammash, A. Moor, D. J. Müller, M. Nash, R. Platt, J. Stelling, B. Treutlein|
|Abstract||This course provides an overview of modern concepts of bioengineering across different levels of complexity, from single molecules to systems, microscaled reactors to production environments, and across different fields of applications|
|Objective||Students will be able to recognize major developments in bioengineering across different organisms and levels of complexity and be able to relate it to major technological and conceptual advances in the underlying sciences.|
|Content||Molecular and cellular engineering; Synthetic biology: Engineering strategies in biology; from single molecules to systems; downscaling bioengineering; Bioengineering in chemistry, pharmaceutical sciences, and diagnostics, personalized medicine.|
|Lecture notes||Handouts during class|
|Literature||Will be announced during the course|
|636-0107-00L||Microbial Biotechnology||4 credits||3G||S. Panke, M. Jeschek|
|Abstract||Students of this course know and can evaluate modern methods of microbial biotechnology and enzyme technology and understand their relation to modern applications of microbial biotechnology.|
|Objective||Students of this course know and can evaluate modern methods of microbial biotechnology and enzyme technology and understand their relation to modern applications of microbial biotechnology.|
|Content||The course will cover in its main part selected fundamental and advanced topics and methodologies in microbial molecular biotechnology. Major topics include I) Microbial physiology of microbes (prokaryotes and selected fungi), II) Applications of Microbial Biotechnology, III) Enzymes - advanced kinetics and engineering, IV) Principles of in vivo directed evolution, V) System approaches to cell engineering/metabolic engineering, and VI) Trends in Microbial Biotechnology. The course is a mix of lectures and different exercise formats.|
|Lecture notes||Notes will be provided in the forms of handouts.|
|Literature||The course will use selected parts of textbooks and then original scientific publications and reviews.|
|636-0301-00L||Current Topics in Biosystems Science and Engineering|
For doctoral students only.
Master's students cannot receive credits for the seminar.
|2 credits||1S||R. Platt, N. Beerenwinkel, Y. Benenson, K. M. Borgwardt, P. S. Dittrich, M. Fussenegger, A. Hierlemann, D. Iber, M. H. Khammash, A. Moor, D. J. Müller, S. Panke, S. Reddy, T. Schroeder, T. Stadler, J. Stelling, B. Treutlein|
|Abstract||This seminar will feature invited lectures about recent advances and developments in systems biology, including topics from biology, bioengineering, and computational biology.|
|Objective||To provide an overview of current systems biology research.|
|Content||The final list of topics will be available at https://www.bsse.ethz.ch/news-and-events/seminar-series.html|
|636-0507-00L||Synthetic Biology II |
Does not take place this semester.
Students in the MSc Programme Biotechnology may select Synthetic Biology II instead of the Research Project 1.
|8 credits||4A||S. Panke, Y. Benenson, J. Stelling|
|Abstract||7 months biological design project, during which the students are required to give presentations on advanced topics in synthetic biology (specifically genetic circuit design) and then select their own biological system to design. The system is subsequently modeled, analyzed, and experimentally implemented. Results are presented at an international student competition at the MIT (Cambridge).|
|Objective||The students are supposed to acquire a deep understanding of the process of biological design including model representation of a biological system, its thorough analysis, and the subsequent experimental implementation of the system and the related problems.|
|Content||Presentations on advanced synthetic biology topics (eg genetic circuit design, adaptation of systems dynamics, analytical concepts, large scale de novo DNA synthesis), project selection, modeling of selected biological system, design space exploration, sensitivity analysis, conversion into DNA sequence, (DNA synthesis external,) implementation and analysis of design, summary of results in form of scientific presentation and poster, presentation of results at the iGEM international student competition (www.igem.org).|
|Lecture notes||Handouts during course|
|Prerequisites / Notice||The final presentation of the project is typically at the MIT (Cambridge, US). Other competing schools include regularly Imperial College, Cambridge University, Harvard University, UC Berkeley, Princeton Universtiy, CalTech, etc.|
This project takes place between end of Spring Semester and beginning of Autumn Semester. Registration in April.
Please note that the number of ECTS credits and the actual work load are disconnected.