Sven Panke: Catalogue data in Autumn Semester 2016

Name Prof. Dr. Sven Panke
FieldBioprocess Engineering
Bioverfahrenstechnik, Panke
ETH Zürich, BSS G 43.3
Klingelbergstrasse 48
4056 Basel
Telephone+41 61 387 32 09
DepartmentBiosystems Science and Engineering
RelationshipFull Professor

626-0007-AALMicrobial Biotechnology
Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement.

Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit.
4 credits9RS. Panke
AbstractIntroduction into the field of microbial biotechnology, covering possible products of enzyme and fermentation technology.
ObjectiveThe student should be able to identify opportunities for microbial bioprocesses and to go through basic and advanced design procedures for microbial bioprocesses.
ContentBioprocess development - An interdisciplinary challenge
Introduction to engineering calculations
Presentation and analysis of data
Material balances
Energy balances
Unsteady-state material and energy balances
Fluid flow
Mass transfer
Homogeneous rearctions
Heterogeneous reactions
Reactor engineering
LiteraturePauline Doran, Bioprocess Engineering Principles, edition 2013, chapters
1 to 8, 10, 12-14

Other literature:
Nielsen/Villadsen, Bioreaction Engineering Principles (Kluwer)
van´t Riet/Tramper: Basic bioreactor design
Stephanopoulos/Aristidou/Nielsen: Metabolic Engineering
Prerequisites / NoticeThere will be two opportunities for tutorials during the semester.
636-0001-00LSeparations in Biotechnology and Bioprocess Economy6 credits3GS. Panke
AbstractSeparations play an integral part of any biotechnological process. This course aims at enabling students specifically with a chemistry/biology background to select & roughly design suitable separation processes for typical biotechnological products such as monoclonal antibodies, antibiotics, and fine chemicals and at providing a basic set of purification operations & judge on process economy.
ObjectiveStudents should be able to select for a given biotechnological product a suitable set of purification operations and judge on process economy.
ContentIntroduction – membrane operations – adsorption and chromatography – crystallization – overall process economics –
Lecture notesHandouts during course
636-0301-00LCurrent Topics in Biosystems Science and Engineering2 credits1ST. Stadler, N. Beerenwinkel, Y. Benenson, K. M. Borgwardt, P. S. Dittrich, M. Fussenegger, A. Hierlemann, D. Iber, M. H. Khammash, D. J. Müller, S. Panke, P. Pantazis, R. Paro, R. Platt, S. Reddy, T. Schroeder, J. Stelling
AbstractThis seminar will feature invited lectures about recent advances and developments in systems biology, including topics from biology, bioengineering, and computational biology.
ObjectiveTo provide an overview of current systems biology research.
ContentThe final list of topics will be available at
636-0507-00LSynthetic Biology II Restricted registration - show details 4 credits4AS. Panke, Y. Benenson, J. Stelling
Abstract7 months biological design project, during which the students are required to give presentations on advanced topics in synthetic biology (specifically genetic circuit design) and then select their own biological system to design. The system is subsequently modeled, analyzed, and experimentally implemented. Results are presented at an international student competition at the MIT (Cambridge).
ObjectiveThe students are supposed to acquire a deep understanding of the process of biological design including model representation of a biological system, its thorough analysis, and the subsequent experimental implementation of the system and the related problems.
ContentPresentations on advanced synthetic biology topics (eg genetic circuit design, adaptation of systems dynamics, analytical concepts, large scale de novo DNA synthesis), project selection, modeling of selected biological system, design space exploration, sensitivity analysis, conversion into DNA sequence, (DNA synthesis external,) implementation and analysis of design, summary of results in form of scientific presentation and poster, presentation of results at the iGEM international student competition (
Lecture notesHandouts during course
Prerequisites / NoticeThe final presentation of the project is typically at the MIT (Cambridge, US). Other competing schools include regularly Imperial College, Cambridge University, Harvard University, UC Berkeley, Princeton Universtiy, CalTech, etc.

This project takes place between end of Spring Semester and beginning of Autumn Semester. Registration in April.

Please note that the number of ECTS credits and the actual work load are disconnected.