Manfred Kopf: Catalogue data in Spring Semester 2015 |
| Name | Prof. Dr. Manfred Kopf |
| Field | Molecular Biomedicine |
| Address | Inst. f. Molecular Health Sciences ETH Zürich, HPL G 12 Otto-Stern-Weg 7 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 64 70 |
| manfred.kopf@biol.ethz.ch | |
| URL | https://mhs.biol.ethz.ch/research/kopf.html |
| Department | Biology |
| Relationship | Full Professor |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 376-0008-00L | Advanced Anatomy and Physiology II   Only for Health Sciences and Technology BSc. | 4 credits | 4V | M. Ristow, M. Detmar, M. Flück, M. Kopf, W. Langhans, C. Spengler, C. Wolfrum, further lecturers | |
| Abstract | In-depth theory to molecular and pathophysiological aspects of nerves, muscles, heart , circulatory , respiratory and sensory organs . | ||||
| Learning objective | In-depth knowledge of anatomy and physiology. | ||||
| Content | Molecular fundamentals of physiological processes, processes of disease development. | ||||
| 376-0150-00L | Anatomy II, Physiology II and Histology | 6 credits | 4V + 2G | M. Ristow, D. P. Wolfer, G. Colacicco, M. Kopf, W. Langhans, L. Slomianka, C. Spengler, C. Wolfrum | |
| Abstract | Basic knowledge of the anatomy and physiology of the gastrointestinal tract, endocrine organs, urinary system and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology. Study of all human tissues and selected organs by examining slides under the light microscope. | ||||
| Learning objective | Foundations of human anatomy and physiology and basics of clinical pathophysiology | ||||
| Content | Short overview of human anatomy, physiology and general pathology. 3rd semester: Principles of histology and embryology. Anatomy and physiology: nervous system, muscle, sensory organs, circulatory system, respiratory system. 4rd semester: Anatomy and physiology: gastrointestinal tract, endocrine system, metabolism and thermoregulation, integumentary system, blood and immune system, urinary system, circadian rhythm, reproductive system, pregnancy and birth. | ||||
| Literature | Anatomie: Martini, Timmons, Tallitsch, "Anatomie", Pearson; oder Schiebler, Korf, "Anatomie", Steinkopff / Springer; Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen, Wissenschaftliche Verlagsgesellschaft, Stuttgart oder Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg | ||||
| Prerequisites / Notice | Der Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut. | ||||
| 376-0152-00L | Anatomy II and Physiology II | 4 credits | 4V | M. Ristow, M. Kopf, W. Langhans, L. Slomianka, C. Spengler, C. Wolfrum | |
| Abstract | Basic knowledge of the anatomy and physiology of the gastrointestinal tract, endocrine organs, urinary system and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology. Study of all human tissues and selected organs by examining slides under the light microscope. | ||||
| Learning objective | Foundations of human anatomy and physiology and basics of clinical pathophysiology | ||||
| Content | Short overview of human anatomy, physiology and general pathology. 3rd semester: Principles of histology and embryology. Anatomy and physiology: nervous system, muscle, sensory organs, circulatory system, respiratory system. 4rd semester: Anatomy and physiology: gastrointestinal tract, endocrine system, metabolism and thermoregulation, integumentary system, blood and immune system, urinary system, circadian rhythm, reproductive system, pregnancy and birth. | ||||
| Literature | Anatomie: Martini, Timmons, Tallitsch, "Anatomie", Pearson; oder Schiebler, Korf, "Anatomie", Steinkopff / Springer; oder Spornitz, "Anatomie und Physiologie, Lehrbuch und Atlas für Pflege-und Gesundheitsfachberufe", Springer Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen, Wissenschaftliche Verlagsgesellschaft, Stuttgart oder Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg | ||||
| Prerequisites / Notice | Der Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut. | ||||
| 376-0173-00L | Physiology II | 3 credits | 2V | M. Ristow, M. Kopf, W. Langhans, C. Spengler, C. Wolfrum | |
| Abstract | Basic knowledge of the anatomy and physiology of the urinary system, the brain and cranial nerves, the special senses and the reproductive system. Knowlewdge of the basic mechanisms of pathobiology, exemples of problems of applied physiology. Study of all human tissues and organs by examining slides under the light microscope. | ||||
| Learning objective | Foundations of human anatomy and physiology and basics of clinical pathophysiology. | ||||
| Content | Short overview of human anatomy, physiology and general pathology. 3rd semester: Cytology, histology, muscular and nervous tissue, embryology, blood, heart, blood vessels, lymphatic and immune system,respiratory system, digestive system, endocrine system, integumentary system. 4rd semester: Urinary system, water, electrolyte, and acid-base balance, male and female reproductive system, pregnancy and child birth, general pathology, neuroanatomy, sense organs, applied physiology. | ||||
| Lecture notes | Müntener und Wolfer: "Anatomie und Physiologie"; www.pharma.ethz.ch/en/teaching/dipl.stud/course.materialsdipl.stud.html | ||||
| Literature | Anatomie: Spornitz U.M.: Anatomie und Physiologie, Lehrbuch und Atlas für Pflege-und Gesundheitsfachberufe, Springer Verlag, Heidelberg Physiologie: Thews/Mutschler/Vaupel: Anatomie, Physiologie, Pathophysiologie des Menschen, Wissenschaftliche Verlagsgesellschaft, Stuttgart oder Schmidt/Lang/Thews: Physiologie des Menschen, Springer-Verlag, Heidelberg | ||||
| Prerequisites / Notice | Der Besuch der Anatomie und Physiologie I - Vorlesung ist Voraussetzung, da die Anatomie und Physiologie II - Vorlesung auf dem Wissen der im vorangegangenen Semester gelesenen Anatomie und Physiologie I - Vorlesung aufbaut. | ||||
| 551-0102-01L | Fundamentals of Biology I Registrations via myStudies until Sunday 1.2.2015, at the latest. Subsequent registrations will not be considered. | 6 credits | 8P | P. Kallio, T. A. Beyer, F. Caudron, M. Gstaiger, M. Kopf, O. Kötting, R. Kroschewski, M. Künzler, D. Ramseier, M. Stoffel, E. B. Truernit, Professors | |
| Abstract | This 1st year Laboratory course introduces the student to the entire range of classical and modern molecular biosciences. During this course (Praktikum GL Bio I) the students will do three experiments in: - Biochemistry - Cell Biology I - Microbiology - Plant Anantomy & Ecology (total of 12 experiments) Each experiment takes one full day. | ||||
| Learning objective | Introduction to theoretical and experimental biology www-link for general Praktikum-information and course material: under https://moodle-app2.let.ethz.ch/course/view.php?id=1151 The general Praktikum information (Assignment list, Instructions and Schedule & Performance Sheet) will also be sent to the students directly (E-mail). | ||||
| Content | The class is divided into four blocks: Biochemistry, Microbiology, Plant biology & Ecology and Cell Biology I. BIOCHEMISTRY: - TAQ Analysis (part 1): Protein purification - TAQ Analysis (part 2): SDS-Gelelektrophoresis - TAQ Analysis (part 3): Activity test of the purified protein MICROBIOLOGY: Day 1: Basics for the work with microorganisms & Isolation of microorganisms from the environment Day 2: Morphology and diagnostics of bacteria & Antimicrobial agents Day 3: Morphology of fungi & Microbial physiology and interactions PLANT BIOLOGY & ECOLOGY - Microscopy and plant cell anatomy - Plant organ anatomy and gene expression - Ecology CELL BIOLOGY I: - Anatomy of mouse & Blood cell determination - Histology - Chromosome preparation and analysis | ||||
| Lecture notes | Laboratory manuals BIOCHEMISTRY: - The protocols can be downloaded from: https://moodle-app2.let.ethz.ch/course/view.php?id=1151 MICROBIOLOGY: - The protocols can be found from: https://moodle-app2.let.ethz.ch/course/view.php?id=1151 - You HAVE TO print the pdf-file, which is also used as the lab manual during the experiments. Therefore, you have to have the Script always with you, when doing the experiments in Microbiology. PLANT BIOLOGY & ECOLOGY: - The protocols can be found from: https://moodle-app2.let.ethz.ch/course/view.php?id=1151 CELL BIOLOGY I: - The handouts of the experiments entitled "Histology" will be provided - The protocols of "Anatomy of mouse & Blood cell determination" and "Chromosome preparation and analysis" can be found from: https://moodle-app2.let.ethz.ch/course/view.php?id=1151 | ||||
| Literature | None | ||||
| Prerequisites / Notice | PLEASE NOTE THE FOLLOWING RULES Your attendance is obligatory and you have to attend all 12 Praktikum days of GL Bio II. Absences are only acceptable if you are able to provide a Doctor’s certificate. If there will be any exceptional or important situations then you should directly contact the Students Advisor of D-Biol, who will decide if you are allowed to miss a Praktikum day or not. HIGHLY IMPORTANT!! 1. Due to the increased number of students, the official Praktikum registration has to be done, using myStudies, preferably at the end of HS14 but not later than Sunday February 1, 2015. 2. Later registration is NOT possible and can NOT be accepted! 3. The course registration for FS2015 is usually possible at the end of HS14 and you will obtain an E-mail from the Rectorate when the course registration using myStudies is possible. Extra Praktikum days have to be organized if more than 240 students will attend the Praktikum. The reserved Extra Praktikum days are: - May 28, June 1 - 2, 2015 (Group I) - June 3 - 5, 2015 (Group II) The group division is random. The Praktikum GL BioI will take place during the following days and therefore, you have to make sure already now that you will not have any other activities / commitments during these days: PRAKTIKUM DAYS FS15: - 19.2.2015 - 26.2 - 5.3 - 12.3 - 19.3 - 26.3 - 2.4 3.4 - 12.4.2015 Eastern & Spring vacation - 16.4 - 23.4 - 30.4 - 7.5 - 21.5 EXTRA PRAKTIKUM DAYS (if necessary) - 28.5.2015 - 1.6 - 2.6 - 3.6 - 4 .6 - 5.6 | ||||
| 551-0318-00L | Immunology II | 3 credits | 2V | M. Kopf, S. R. Leibundgut, A. Oxenius, E. Slack, further lecturers | |
| Abstract | Introduction into the cellular and molecular basis of the immune system and immune responses against diverse pathogens, tumors, transplants, and self (autoimmunity) | ||||
| Learning objective | The lectures will provide a detailed understanding: - how innate and adaptive immune responses interact at the cellular and molecular level. - how the immune system recognizes and fights against pathogenic microorganisms including viruses, bacteria, and parasites. - why lymphocytes tolerate self molecules. - about function and dysfunction the intestinal immune system. - immunopathology and inflammatory diseases. | ||||
| Content | The aim of lecture is to understand: > the immunological complement system > migration and homing of immune cells > the intestinal immune system > tumor immunology > tolerance and autoimmunity > T cell memory > pathogen associated molecular patterns > Immune defense against viruses, bacteria, fungi, and parasites | ||||
| Lecture notes | lecture presentations can be downloaded at: https://moodle-app2.let.ethz.ch/course/view.php?id=1221 | ||||
| Literature | Recommended: Kuby Immunology (Freeman) | ||||
| 551-0396-01L | Immunology I Number of participants limited to 24 Prerequisites: Attendance of the concept courses Immunology I (551-0317-00L) and Immunology II (551-0318-00L) | 6 credits | 7G | A. Oxenius, M. Bachmann, B. Becher, K. Frei, M. Groettrup, M. Kopf, T. Kündig, B. Ludewig, T. B. Suter, M. van den Broek | |
| Abstract | This block course teaches a wide selection of practical immunological techniques and offers advanced lectures in selected topics in immunology. | ||||
| Learning objective | The aim of this block course is the acquaintance with a wide spectrum of immunological techniques involving practical experimental work following analysis and interpretation of the experimental data. Along the practical work, advanced lectures in selected topics in immunology, based on the knowledge from the immunology concept course, will be offered. Furthermore, students will have the opportunity to read, interpret and present current papers followed scientific discussions. | ||||
| Content | The aim of this block course is the acquaintance with a wide spectrum of immunological techniques involving practical experimental work following analysis and interpretation of the experimental data. Along the practical work, advanced lectures in selected topics in immunology, based on the knowledge from the immunology concept course, will be offered. Furthermore, students will have the opportunity to read, interpret and present current papers followed scientific discussions. | ||||
| Lecture notes | A script for the course will be available online (the link will be provided in the immunology concept lecture, 551-0318-00L). | ||||
| Prerequisites / Notice | Requirement for the registration for this block course is the attendance of the immunology concept courses 551-0317-00L and 551-0318-00L. Evaluation of achievements is done on an individual basis by each participating lecturer. | ||||
| 551-0509-00L | Current Immunological Research in Zürich | 0 credits | 1K | R. Spörri, M. Detmar, C. Halin Winter, W.‑D. Hardt, M. Kopf, A. Lanzavecchia, S. R. Leibundgut, A. Oxenius, University lecturers | |
| Abstract | This monthly meeting is a platform for Zurich-based immunology research groups to present and discuss their ongoing research projects. At each meeting three PhD students or Postdocs from the participating research groups present an ongoing research project in a 30 min seminar followed by a plenary discussion. | ||||
| Learning objective | The aim of this monthly meeting is to provide further education for master and doctoral students as well as Postdocs in diverse topics of immunology and to give an insight in the related research. Furthermore, this platform fosters the establishment of science- and technology-based interactions between the participating research groups. | ||||
| Content | Presentation and discussion of current research projects carried out by various immunology-oriented research groups in Zurich. | ||||
| Lecture notes | none | ||||
| 551-1100-00L | Infectious Agents: From Molecular Biology to Disease Number of participants limited to 22. Requires application; selected applicants will be notified before the first week of lectures. | 4 credits | 2S | W.‑D. Hardt, L. Eberl, U. F. Greber, A. B. Hehl, M. Kopf, S. R. Leibundgut, A. Oxenius, L. Pelkmans, P. Sander | |
| Abstract | Literature seminar for students at the masters level and PhD students. Introduction to the current research topics in infectious diseases; Introduction to key pathogens which are studied as model organisms in this field; Overview over key research groups in the field of infectious diseases in Zürich. | ||||
| Learning objective | Working with the current research literature. Getting to know the key pathogens serving as model organisms and the research technologies currently used in infection biology. | ||||
| Content | for each model pathogen (or key technology): 1. introduction to the pathogen 2. Discussion of one current research paper. The paper will be provided by the respective supervisor. He/she will give advice (if required) and guide the respective literature discussion. | ||||
| Lecture notes | Teachers will provide the research papers to be discussed. Students will prepare handouts for the rest of the group for their assigned seminar. | ||||
| Literature | Teachers will provide the research papers to be discussed. | ||||
| Prerequisites / Notice | Restricted to max 20 students. Please sign up before 6.2.2015 via e-mail to micro_secr@micro.biol.ethz.ch and include the following information: 551-1100-00L; your name, your e-mail address, university/eth, students (specialization, semester), PhD students (research group, member of a PhD program? which program?). The 20 students admitted to this seminar will be selected and informed by e-mail until 7.2.2015 by W.-D. Hardt. The first seminar date will serve to form groups of students and assign a paper to each group. | ||||
| 551-1118-00L | Cutting Edge Topics: Immunology and Infection Biology II | 2 credits | 1S | A. Oxenius, M. Bachmann, B. Becher, C. Halin Winter, M. Kopf, S. R. Leibundgut, C. Münz, A. Trkola, M. van den Broek | |
| Abstract | Weekly seminar about cutting edge topics in immunology and infection biology. Internationally renowned experts present their current research followed by an open discussion. | ||||
| Learning objective | Weekly seminar about cutting edge topics in immunology and infection biology. Internationally renowned experts present their current research followed by an open discussion. The aim of this course is to confront students with current research topics and with scientific presentation. The course offers the opportunity to gain in depth knowledge about diverse topics which are often only briefly touched in the concept courses and to engage in discussion with experts in the field. | ||||
| Content | Immunology and infection biology. The specific topics are variable and depend each semester on the list of invited experts. | ||||
| 551-1400-00L | Molecular Disease Mechanisms II | 6 credits | 4V | C. Wolfrum, M. Kopf, S. J. Sturla, further lecturers | |
| Abstract | In this course the mechanisms of disease development will be studied. Main topics will be: 1. Influence of environmental factors with an emphasis on inflammation and the immune response. 2. Mechanisms underlying disease progression in metabolic disorders, integrating genetic and environmental factors. 3. Mechanisms underlying disease progression in cancer, integrating genetic and environment | ||||
| Learning objective | To understand the mechanisms governing disease development with a special emphasis on genetic and environmental associated components | ||||
| Lecture notes | All information can be found at: https://moodle-app2.let.ethz.ch/course/view.php?id=690 The enrollment key will be provided by email | ||||