Ruth Kroschewski: Catalogue data in Autumn Semester 2022
|Dr. Ruth Kroschewski
Institut für Biochemie
ETH Zürich, HPM D 11.3
|+41 44 632 63 46
|+41 44 632 15 91
|Cell Biology of the Nucleus
Number of participants limited to 18.
The enrolment is done by the D-BIOL study administration.
|R. Kroschewski, Y. Barral, M. Jagannathan, S. Jessberger, K. Weis
|Introduction to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems.
|The aim of our course is to introduce the students to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems. Emphasis is given to:
• Establishment of nuclear identity and nuclear-cytoplasmic communication
• Reorganization of the nucleus in aging
• Animal cells during the generation of cell diversity and neuronal differentiation
By the end of the course, based on lectures, literature reading and practical lab work, the students will be able to formulate open questions concerning the function of the nucleus. Thus, the students will know about the mechanisms and consequences of nuclear-cytoplasmic compartmentalization, nuclear positioning, DNA clustering in the nucleus and cytoplasm during cell divisions and aging.
|During this block-course, the students will
- learn how organelles establish and maintain identity with a focus on the nucleus
- discover the evolutionary and functional plasticity of the nucleus
- design, apply, evaluate and compare experimental strategies
Students - in groups of 2 or max. 3 - will be integrated into a research project connected to the subject of the course, within one of the participating research groups.
Lectures and technical notes will be given and informal discussions held to provide you with the theoretical background.
|There will be optional papers to be read before the course start. They serve as framework orientation for the practical parts of this block course and will be made accessible to you shortly before the course starts on the relevant Moodle site.
|Documentation and recommended literature (review articles) will be provided during the course.
|Cellular Biochemistry of Health and Disease
Number of participants limited to 20.
|V. Korkhov, T. Ishikawa, M. Jagannathan, R. Kroschewski, G. Neurohr, M. Peter, A. E. Smith, B. Snijder, K. Weis
|During this Masters level seminar style course, students will explore current research topics in cellular biochemistry focused on the structure, function and regulation of selected cell components, and the consequences of dysregulation for pathologies.
|Students will work with experts toward a critical analysis of cutting-edge research in the domain of cellular biochemistry, with emphasis on normal cellular processes and the consequences of their dysregulation. At the end of the course, students will be able to introduce, present, evaluate, critically discuss and write about recent scientific articles in the research area of cellular biochemistry.
|Guided by an expert in the field, students will engage in classical round-table style discussions of current literature with occasional frontal presentations. Students will alternate as discussion leaders throughout the semester, with the student leader responsible to briefly summarize key general knowledge and context of the assigned primary research paper. Together with the faculty expert, all students will participate in discussion of the primary paper, including the foundation of the biological question, specific questions addressed, key methods, key results, remaining gaps and research implications.
|The literature will be provided during the course
|Prerequisites / Notice
|The course will be taught in English.