Yves Barral: Catalogue data in Autumn Semester 2021 |
Name | Prof. Dr. Yves Barral |
Field | Biochemie |
Address | Institut für Biochemie ETH Zürich, HPM D 8.3 Otto-Stern-Weg 3 8093 Zürich SWITZERLAND |
Telephone | +41 44 632 06 78 |
Fax | +41 44 632 15 91 |
yves.barral@bc.biol.ethz.ch | |
Department | Biology |
Relationship | Full Professor |
Number | Title | ECTS | Hours | Lecturers | |
---|---|---|---|---|---|
551-0103-AAL | Fundamentals of Biology II: Cell Biology Enrolment ONLY for MSc students with a decree declaring this course unit as an additional admission requirement. Any other students (e.g. incoming exchange students, doctoral students) CANNOT enrol for this course unit. | 5 credits | 11R | U. Kutay, Y. Barral, G. Schertler, U. Suter, S. Werner | |
Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Learning objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | ||||
Literature | Alberts et al. 'Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback). Topic/Lecturer/Chapter/Pages: Analyzing cells & molecules / Gebhard Schertler/8/ 439-463; Membrane structure / Gebhard Schertler/ 10/ 565-595; Compartments and Sorting/ Ulrike Kutay/12+14+6/641-694/755-758/782-783/315-320/325 -333/Table 6-2/Figure6-20, 6-21, 6-32, 6-34; Intracellular Membrane Traffic/ Ulrike Kutay/13/695-752; The Cytoskeleton/ Ulrike Kutay/ 16/889 - 948 (only the essentials); Membrane Transport of Small Molecules and the Electrical Properties of Membranes /Sabine Werner/11/597 - 633; Mechanisms of Cell Communication / Sabine Werner/15/813-876; Cancer/ Sabine Werner/20/1091-1141; Cell Junctions and Extracellular Matrix/Ueli Suter / 1035-1081; Stem Cells and Tissue Renewal/Ueli Suter /1217-1262; Development of Multicellular organisms/ Ernst Hafen/ 21/ 1145-1179 /1184-1198/1198-1213; Cell Migration/Joao Matos/951-960; Cell Death/Joao Matos/1021-1032; Cell Cycle/chromosome segregation/Cell division/Meiosis/Joao Matos/ 963-1018. | ||||
Prerequisites / Notice | none | ||||
551-0103-00L | Fundamentals of Biology II: Cell Biology Only for - Biologie BSc (Programme Regulations 2013), - Pharmaceutical Sciences BSc (Programme Regulations 2013) - Health Sciences and Technology BSc (Programme Regulations 2017) | 5 credits | 5V | S. Werner, Y. Barral, U. Kutay, G. Schertler, U. Suter, I. Zemp | |
Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Learning objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | ||||
Lecture notes | The lectures are presented in the Powerpoint format. These are available on the WEB for ETH students over the nethz (Moodle). Some lectures are available on the ETH WEB site in a live format (Livestream) at the above WEB site. | ||||
Literature | The lectures follow Alberts et al. `Molecular Biology of the Cell' 6th edition, 2014, ISBN 9780815344322 (hard cover) and ISBN 9780815345244 (paperback). | ||||
Prerequisites / Notice | Some of the lectures are given in the English language. Certain sections of the text-book must be studied by self-instruction. | ||||
551-0309-00L | Concepts in Modern Genetics Information for UZH students: Enrolment to this course unit only possible at ETH. No enrolment to module BIO348 at UZH. Please mind the ETH enrolment deadlines for UZH students: Link | 6 credits | 4V | Y. Barral, D. Bopp, A. Hajnal, O. Voinnet | |
Abstract | Concepts of modern genetics and genomics, including principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | ||||
Learning objective | This course focuses on the concepts of classical and modern genetics and genomics. | ||||
Content | The topics include principles of classical genetics; yeast genetics; gene mapping; forward and reverse genetics; structure and function of eukaryotic chromosomes; molecular mechanisms and regulation of transcription, replication, DNA-repair and recombination; analysis of developmental processes; epigenetics and RNA interference. | ||||
Lecture notes | Scripts and additional material will be provided during the semester. | ||||
551-0337-00L | Cell Biology of the Nucleus Number of participants limited to 18. The enrolment is done by the D-BIOL study administration. General safety regulations for all block courses: The COVID certificate is mandatory at ETH Zurich. Only students who have a Covid certificate, i.e. who have been vaccinated, have recovered or have been tested, are entitled to attend courses in attendance. -Whenever possible the distance rules have to be respected -All students have to wear masks throughout the course. Please keep reserve masks ready. Surgical masks (IIR) or medical grade masks (FFP2) without a valve are permitted. Community masks (fabric masks) are not allowed. -The installation and activation of the Swiss Covid-App is highly encouraged -Any additional rules for individual courses have to be respected -Students showing any COVID-19 symptoms are not allowed to enter ETH buildings and have to inform the course responsible. | 6 credits | 7P | R. Kroschewski, Y. Barral, M. Jagannathan, S. Jessberger, K. Weis | |
Abstract | Introduction to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems. | ||||
Learning objective | The aim of our course is to introduce the students to the organizational principles of the nucleus using budding yeast, drosophila and vertebrate cells as model systems. Emphasis is given to: • Establishment of nuclear identity and nuclear-cytoplasmic communication • Reorganization of the nucleus in aging • Animal cells during the generation of cell diversity and neuronal differentiation By the end of the course, based on lectures, literature reading and practical lab work, the students will be able to formulate open questions concerning the function of the nucleus. Thus, the students will know about the mechanisms and consequences of nuclear-cytoplasmic compartmentalization, nuclear positioning, DNA clustering in the nucleus and cytoplasm during cell divisions and aging. | ||||
Content | During this block-course, the students will - learn how organelles establish and maintain identity with a focus on the nucleus - discover the evolutionary and functional plasticity of the nucleus - design, apply, evaluate and compare experimental strategies Students - in groups of 2 or max. 3 - will be integrated into a research project connected to the subject of the course, within one of the participating research groups. Lectures and technical notes will be given and informal discussions held to provide you with the theoretical background. | ||||
Lecture notes | There will be optional papers to be read before the course start. They serve as framework orientation for the practical parts of this block course and will be made accessible to you shortly before the course starts on the relevant Moodle site. | ||||
Literature | Documentation and recommended literature (review articles) will be provided during the course. | ||||
551-0973-00L | Specialized Biology Course with an Educational Focus: Evolution | 6 credits | 2G + 13A | H. Stocker, Y. Barral, K. Köhler | |
Abstract | Specialist aspects of biology with a focus on evolution are covered from the angle of imparting these to pupils, their historical development, and their significance for the subject, the individual and society. | ||||
Learning objective | After successful completion of the module, students should be able - to retrieve in-depth knowledge of biology with a special focus on evolution and to impart this to others. - to analyse controversial topics and to give factual explanations for these. - to conduct more in-depth work on a research topic and to compile a tuition unit based on this topic - to prepare tuition units involving complex learning matter at a high specialist level which are suitably tailored to the recipients, and to teach these in a manner conducive to learning. | ||||
Content | Selected biological topics, with a special focus on evolution, are dealt with under consideration of the special needs of persons involved in teaching. The module comprises lectures, a book club, and a seminar thesis. | ||||
Lecture notes | Teaching materials are available online on Moodle. | ||||
Literature | Literature and references are posted online on Moodle. | ||||
Prerequisites / Notice | The Specialized Biology Course with an Educational Focus consists of two modules (6 CP each). In the fall semester, the focus is on evolution. The module of the spring semester deals with biological concepts. Students attending both modules can start with either module. Performance is assessed during the course of the entire module. Active participation in the course is required. The thesis (including oral presentation) has to be completed. The Specialized Biology Course with an Educational Focus (6+6 CP) can be acknowledged, in agreement with the advisor of the respective elective major, as one of the two obligatory research projects (each 15 CP). In such a case, additional 3 CP must be obtained in another course. In case of overbooking of the course, students enrolled in the Teaching Diploma in Biology will have priority. |