Yves Barral: Catalogue data in Spring Semester 2015 |
| Name | Prof. Dr. Yves Barral |
| Field | Biochemie |
| Address | Institut für Biochemie ETH Zürich, HPM D 8.3 Otto-Stern-Weg 3 8093 Zürich SWITZERLAND |
| Telephone | +41 44 632 06 78 |
| Fax | +41 44 632 15 91 |
| yves.barral@bc.biol.ethz.ch | |
| Department | Biology |
| Relationship | Full Professor |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 227-0396-00L | EXCITE Interdisciplinary Summer School on Bio-Medical Imaging   The school admits 60 MSc or PhD students with backgrounds in biology, chemistry, mathematics, physics, computer science or engineering based on a selection process. Students have to apply for acceptance by 27 April 2015. To apply a curriculum vitae and an application letter need to be submitted. Further information can be found at: www.excite.ethz.ch. | 3 credits | 6G | S. Kozerke, Y. Barral, G. Csúcs, G. Székely, R. A. Wepf, M. P. Wolf | |
| Abstract | Two-week summer school organized by EXCITE (Center for EXperimental & Clinical Imaging TEchnologies Zurich) on biological and medical imaging. The course covers X-ray imaging, magnetic resonance imaging, nuclear imaging, ultrasound imaging, infrared and optical microscopy, electron microscopy, image processing and analysis. | ||||
| Learning objective | Students understand basic concepts and implementations of biological and medical imaging. Based on relative advantages and limitations of each method they can identify preferred procedures and applications. Common foundations and conceptual differences of the methods can be explained. | ||||
| Content | Two-week summer school on biological and medical imaging. The course covers concepts and implementations of X-ray imaging, magnetic resonance imaging, nuclear imaging, ultrasound imaging, infrared and optical microscopy and electron microscopy. Multi-modal and multi-scale imaging and supporting technologies such as image analysis and modeling are discussed. Dedicated modules for physical and life scientists taking into account the various backgrounds are offered. | ||||
| Lecture notes | Hand-outs, Web links | ||||
| Prerequisites / Notice | The school admits 60 MSc or PhD students with backgrounds in biology, chemistry, mathematics, physics, computer science or engineering based on a selection process. To apply a curriculum vitae, a statement of purpose and applicants references need to be submitted. Further information can be found at: www.excite.ethz.ch/education/summer_school. | ||||
| 551-0103-AAL | Fundamentals of Biology II: Cell Biology Enrolment only for MSc students who need this course as additional requirement. | 5 credits | 11R | U. Kutay, Y. Barral, E. Hafen, G. Schertler, U. Suter, S. Werner | |
| Abstract | The goal of this course is to provide students with a wide general understanding in cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
| Learning objective | The goal of this course is to provide students with a wide general understanding cell biology. With this material as a foundation, students have enough of a cell biological basis to begin their specialization not only in cell biology but also in related fields such as biochemistry, microbiology, pharmacological sciences, molecular biology, and others. | ||||
| Content | The focus is animal cells and the development of multicellular organisms with a clear emphasis on the molecular basis of cellular structures and phenomena. The topics include biological membranes, the cytoskeleton, protein sorting, energy metabolism, cell cycle and division, viruses, extracellular matrix, cell signaling, embryonic development and cancer research. | ||||
| Literature | Alberts et al. ‘Molecular Biology of the Cell’ Fifth edition, 2008 ISBN 978-0-8153-4105-5 (hard cover) and ISBN 978-0-8153-4106-2 (paperback). Topic/Lecturer/Chapter/Pages: Introduction to Cell Biology/Gebhard Schertler/1+2+3+4/1-193; Cellular compartments/Gebhard Schertler/12/695-748; Membrane lipids/Gebhard Schertler/10/617-629; Working with cells/Ulrike Kutay/9/579-613; Mitochondria/Ulrike Kutay/12+14/695-703/713-723/815-818/856-860; Chloroplasts, peroxisomes/Ulrike Kutay/12+14/695-703/713-723/840-844/856-860; Structure and dynamics of the nucleus/Ulrike Kutay/6+12/362-366/704-706/710-712; Membrane proteins/Gebhard Schertler/10/629-650; Working with membranes/Gebhard Schertler/9/579-615; Nuclear transport of proteins/Ulrike Kutay/12/706-711; RNA processing and nuclear export/Ulrike Kutay/6/345-353/357-366/369; Endoplasmic reticulum/Ulrike Kutay/12/723-745; Vesicular transport/Ulrike Kutay/13/749-766; From the ER through the Golgi/Ulrike Kutay/13/766-779; From the TGN to Lysosomes and the plasma membrane/Ulrike Kutay/13/779-787/799-809; The plasma membrane and endocytosis/Ulrike Kutay/13/787-799; Introduction to the cytoskeleton/Ulrike Kutay/16/965-1035; Microtubules/Ulrike Kutay/16/965-1035; Actin/Muscle/Ulrike Kutay/16/965-1035; Cell polarization and migration/Yves Barral/16/1036-1052; Introduction to the cell cycle/Yves Barral/17/1053-1070; MPF and the cell cycle control machinery/Yves Barral/17/1053-1070; Mechanisms of chromosome segregation/Yves Barral/17/1070-1090; Cell division/Yves Barral/17/1090-1101; Apoptosis/Yves Barral/18/1115-1127; Membrane transport passive and active/Sabine Werner/11/651-667; Ion channels, action potential/Sabine Werner/11/667-687; General principles of signalling/Sabine Werner/15/879-903; Nuclear receptors, G-protein coupled receptors/Sabine Werner/15/879-921; Cell signalling; G-protein coupled receptors/Sabine Werner/15/904-921; Cell signalling; Receptor tyrosine kinases/Sabine Werner/15/921-938; Cell signalling; Tyrosine kinase associated receptors/Sabine Werner/15/921-938; Cell signalling; Receptor serine threonine kinases/Sabine Werner/15/939-944; Signalling through proteolysis/Sabine Werner/15/946-954; Cancer Biology/Sabine Werner/20/1205-1267; Cell-Cell Interactions/Ueli Suter/19/1131-1195; Extracellular Matrix/Ueli Suter/19/1131-1195; Regeneration / Stem Cells/Ueli Suter/23/1417-1484; Germ Cells and Sex Determination/Ernst Hafen/21/1269-1304; Development/Ernst Hafen/22/1305-1417 | ||||
| Prerequisites / Notice | none | ||||
| 551-0320-00L | Cellular Biochemistry (Part II) | 3 credits | 2V | Y. Barral, R. Kroschewski, A. E. Smith | |
| Abstract | This course will focus on molecular mechanisms and concepts underlying cellular biochemistry, providing advanced insights into the structural and functional details of individual cell components, and the complex regulation of their interactions. Particular emphasis will be on the spatial and temporal integration of different molecules and signaling pathways into global cellular processes. | ||||
| Learning objective | The full-year course (551-0319-00 & 551-0320-00) focuses on the molecular mechanisms and concepts underlying the biochemistry of cellular physiology, investigating how these processes are integrated to carry out highly coordinated cellular functions. The molecular characterization of complex cellular functions requires a combination of approaches such as biochemistry, but also cell biology and genetics. This course is therefore the occasion to discuss these techniques and their integration in modern cellular biochemistry. The students will be able to describe the structural and functional details of individual cell components, and the spatial and temporal regulation of their interactions. In particular, they will learn to explain how different molecules and signaling pathways can be integrated during complex and highly dynamic cellular processes such as intracellular transport, cytoskeletal rearrangements, cell motility, and cell division. In addition, they will be able to illustrate the relevance of particular signaling pathways for cellular pathologies such as cancer or during cellular infection. | ||||
| Content | Spatial and temporal integration of different molecules and signaling pathways into global cellular processes, such as cell division, cell infection and cell motility. Emphasis is also put on the understanding of pathologies associated with defective cell physiology, such as cancer or during cellular infection. | ||||
| Literature | Recommended supplementary literature (review articles and selected primary literature) will be provided during the course. | ||||
| Prerequisites / Notice | To attend this course the students must have a solid basic knowledge in chemistry, biochemistry, cell biology and general biology. Biology students have in general already attended the first part of the "Cellular Biochemistry" concept course (551-0319-00). The course will be taught in English. In addition, the course will be based on a blended-learning scenario, where frontal lectures will be complemented with carefully chosen web-based teaching elements that students access through the ETH Moodle platform. | ||||
| 551-0339-00L | Molecular Mechanisms of Cell Dynamics Number of participants limited to 15 | 6 credits | 7G | B. Kornmann, Y. Barral, U. Kutay, M. Peter | |
| Abstract | Application of current strategies to study complex and highly regulated cellular processes during cell division and growth. | ||||
| Learning objective | The students learn to evaluate and to apply the current strategies to study complex and highly regulated cellular processes during cell division and growth. | ||||
| Content | During this Block-Course, the students will learn to (1) describe the main regulators and the mechanics of cell division and growth, (2) perform standard lab techniques and quantitate dynamic cellular processes during cell division and growth, (3) evaluate and compare experimental strategies and model systems, (4) independently search and critically evaluate scientific literature on a specific problem and present it in a seminar, and (5) formulate scientific concepts (preparation and presentation of a poster). Students will work in small groups in individual labs on one research project (8 full days of practical work; every group of students will stay in the same lab during the entire course). The projects are close to the actual research carried out in the participating research groups, but with a clear connection to the subject of the course. | ||||
| Literature | Documentation and recommended literature (review articles and selected primary literature) will be provided during the course. | ||||
| Prerequisites / Notice | This course will be taught in english. | ||||