Sabine Werner: Catalogue data in Autumn Semester 2023 |  |
| Name | Prof. Dr. Sabine Werner |
| Field | Zellbiologie |
| Address | Inst. f. Molecular Health Sciences ETH Zürich, HPL F 12 Otto-Stern-Weg 7 8093 Zürich SWITZERLAND |
| Telephone | +41 44 633 39 41 |
| Fax | +41 44 633 11 74 |
| sabine.werner@biol.ethz.ch | |
| Department | Biology |
| Relationship | Full Professor |
| Number | Title | ECTS | Hours | Lecturers | ||||||||||||||||||||||||||
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| 551-0127-00L | Fundamentals of Biology III: Multicellularity | 8 credits | 6G | M. Stoffel, M. Künzler, O. Y. Martin, U. Suter, S. Werner, A. Wutz, S. C. Zeeman | ||||||||||||||||||||||||||
| Abstract | The lecture conveys the fundamental concepts underlying multicellularity with an emphasis on the molecular basis of multicellular biological systems and their functional integration into coherent wholes. The structural and functional specialization in multicellular organisms will be discussed by highlighting common and specific functions in fungi, plants, and animals (including humans). | |||||||||||||||||||||||||||||
| Learning objective | 1.Students can describe advantages and challenges associated with being multicellular and outline independent solutions that organisms have developed to cope with the challenges of complex multicellularity . 2.Students can explain how the internal and external structures of fungi, plants and animals function to support survival, growth, behavior, and reproduction. 3.Students can explain the basic pathways and mechanisms of cellular communication regulating cellular behavior (cell adhesion, metabolism, proliferation, reproduction, development). 4.Students can describe how a single cell develops from one cell into many, each with different specialized functions. | |||||||||||||||||||||||||||||
| Content | The lecture introduces the structural and functional specialization in fungi, plants and animals, including humans. After providing an overview on the diversity of eukaryotic organisms, the lecture will discuss how fungi, plants, animals and humans have evolved structures and strategies to cope with the challenges of multicellularity. The molecular basis underlying communication, coordination and differentiation will be conveyed and complemented by key aspects of reproduction, metabolism development, and regeneration. Topics include form and function of fungi and plants, human anatomy and physiology, metabolism, cell signaling, adhesion, stem cells, regeneration, reproduction, and development. | |||||||||||||||||||||||||||||
| Literature | Alberts et al. 'Molecular Biology of the Cell' 6th edition Smith A.M., et al. “Plant Biology” Garland Science, New York, Oxford Campbell “Biology”, 11th Edition | |||||||||||||||||||||||||||||
| Prerequisites / Notice | Some lecture are held in English. | |||||||||||||||||||||||||||||
Competencies |
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| 551-1511-00L | Parallels Between Tissue Repair and Cancer  Number of participants limited to 20. The enrolment is done by the D-BIOL study administration. | 6 credits | 7P | S. Werner, H. Gehart, M. Schäfer | ||||||||||||||||||||||||||
| Abstract | This course aims at the understanding of the cellular and molecular mechanisms underlying tissue repair processes in response to different insults. The focus will be on repair of the skin and the liver. In addition, we will highlight the parallels and differences between tissue repair and cancer. | |||||||||||||||||||||||||||||
| Learning objective | To learn the cellular and molecular principles underlying tissue repair processes, in particular in the skin and in the liver, and the parallels and differences to cancer. To learn modern technologies in Molecular and Cellular Biology as well as Histology and to use these technologies to study questions related to mechanisms underlying tissue repair and cancer. | |||||||||||||||||||||||||||||
| Content | This course aims at the understanding of the cellular and molecular mechanisms underlying tissue repair processes in response to different insults. The focus will be on repair of the skin and the liver. In addition, we will highlight the parallels and differences between tissue repair and cancer. Experimental approaches include biochemical studies, molecular and cellular studies using cultured cell lines and primary cells, as well as analysis of murine and human tissues. The course combines practical work with lectures, discussions, project preparations and presentations. | |||||||||||||||||||||||||||||
| Lecture notes | siehe Lernmaterialien | |||||||||||||||||||||||||||||