Donald Hilvert: Catalogue data in Autumn Semester 2021

Award: The Golden Owl
Name Prof. em. Dr. Donald Hilvert
FieldOrganische Chemie
Address
Dep. Chemie und Angew. Biowiss.
ETH Zürich, HCI H 327
Vladimir-Prelog-Weg 1-5/10
8093 Zürich
SWITZERLAND
Telephone+41 44 632 31 76
E-maildonald.hilvert@org.chem.ethz.ch
DepartmentChemistry and Applied Biosciences
RelationshipProfessor emeritus

NumberTitleECTSHoursLecturers
529-0731-00LNucleic Acids and Carbohydrates
Note for BSc Biology students: Only one of the two concept courses 529-0731-00 Nucleic Acids and Carbohydrates (autumn semester) or 529-0732-00 Proteins and Lipids (spring semester) can be counted for the Bachelor's degree.
6 credits3GD. Hilvert, P. A. Kast, S. J. Sturla, H. Wennemers
AbstractStructure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines
ObjectiveStructure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines
ContentStructure, function and chemistry of nucleic acids and carbohydrates. DNA/RNA structure and synthesis; recombinant DNA technology and PCR; DNA arrays and genomics; antisense approach and RNAi; polymerases and transcription factors; catalytic RNA; DNA damage and repair; carbohydrate structure and synthesis; carbohydrate arrays; cell surface engineering; carbohydrate vaccines
Lecture notesNo script; illustrations from the original literature relevant to the individual lectures will be provided weekly (typically as handouts downloadable from the Moodle server).
LiteratureMainly based on original literature, a detailed list will be distributed during the lecture
CompetenciesCompetencies
Subject-specific CompetenciesConcepts and Theoriesassessed
Techniques and Technologiesassessed
Method-specific CompetenciesAnalytical Competenciesassessed
Problem-solvingassessed
Social CompetenciesCommunicationassessed
Cooperation and Teamworkassessed
Personal CompetenciesSelf-awareness and Self-reflection assessed
Self-direction and Self-management assessed
529-0733-01LEnzymes6 credits3GD. Hilvert
AbstractPrinciples of enzymatic catalysis, enzyme kinetics, mechanisms of enzyme-catalyzed reactions (group transfer reactions, carbon-carbon bond formation, eliminations, isomerisations and rearrangements), cofactor chemistry, enzymes in organic synthesis and the biosynthesis of natural products, catalytic antibodies.
ObjectiveOverview of enzymes, enzyme-catalyzed reactions and metabolic processes.
ContentPrinciples of enzymatic catalysis, enzyme kinetics, mechanisms of enzyme catalyzed reactions (group transfer reactions, carbon-carbon bond formation, eliminations, isomerisations and rearrangements), cofactor chemistry, enzymes in organic synthesis and the biosynthesis of natural products, catalytic antibodies.
Lecture notesA script will not be handed out.
LiteratureGeneral:
T. Bugg, An Introduction to Enzyme and Coenzyme Chemistry, Blackwell Science Ltd., Oxford, 1997.

In addition, citations from the original literature relevant to the individual lectures will be assigned weekly.