Beate Escher: Catalogue data in Spring Semester 2022 |
| Name | PD Dr. Beate Escher |
| Field | Umweltchemie und Ökotoxikologie |
| Address | UFZ Leipzig Permoser Strasse 15 Department Zelltoxikologie 04318 Leipzig GERMANY |
| Telephone | +49 3412351244 |
| bescher@env.ethz.ch | |
| Department | Environmental Systems Science |
| Relationship | Privatdozentin |
| Number | Title | ECTS | Hours | Lecturers | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
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| 701-0998-00L | Environmental and Human Health Risk Assessment of Chemicals | 3 credits | 2G | M. Scheringer, B. Escher | |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Abstract | Application of methods for chemical risk assessment for human health and the environmental according to European and Swiss regulation; hazard and risk; exposure and effect analysis for different types of chemicals. Estimation of missing chemical properties (QSAR methods); critical evaluation of risk assessment methods, presentation of alternative assessment methods. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Learning objective | The students are familiar with regulatory approaches to human and environmental risk assessment of chemicals and can perform the main steps of a regulatory risk assessment for an industrial chemical. They are aware of pitfalls and challenges and know about new approaches to risk assessment. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Content | Regulatory methods for environmental risk assessment of chemicals (industrial chemicals, pesticides, pharmaceuticals), European regulation REACH, Swiss regulations, international approaches - Human vs. environmental risk assessment - Classification and labelling of chemicals - PBT assessment (persistence, bioaccumulation, toxicity) - Exposure analysis: emission patterns, multimedia fate and transport models for quantifying environmental exposure, Long range transport and persistence, predicted and measured exposure concentration for the environment and humans - Effect analysis: estimation of hazard potential for ecotoxicity and human health, extrapolation methods, classification of chemicals according to modes of toxic action, predictive models (QSAR) - Risk assessment methods (deterministic vs. probabilistic), risk assessment vs. hazard assessment, risk management - uncertainty and sensitivity analyses, precautionary principle - Environmental Quality Assessment (water, sediment, biota), Water Framework Directive) - New methods in environmental risk assessment: mixtures, temporally and spatially explicit risk assessment | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Lecture notes | Slides of lectures, lecture notes for selected chapters and additional reading material will be made available via polybox. Also templates for the exercises and the report will be made available via polybox. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Literature | - Van Leeuwen, C.J., Vermeire, T. (Eds.) Risk Assessment of Chemicals: An Introduction. Springer, 2007 (als e-book in der ETH-Bibliothek verfügbar). - Scheringer, M., Persistence and Spatial Range of Environmental Chemicals. Wiley-VCH, Weinheim, 2002. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
| Prerequisites / Notice | Block course: Lecture and accompanying exercise where students conduct a comprehensive risk assessment for one selected chemical each according to the European regulation for industrial chemicals. The risk assessment will be presented in class and has to be compiled in a written technical report (Chemical dossier) that will be graded. The overall work load is 90 hours with 30 hours contact time (block course) and 60 hours self-study. | ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Competencies |
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