Dario Neri: Catalogue data in Spring Semester 2020

Name	Prof. Dr. Dario Neri
Address	Inst. f. Pharmazeutische Wiss. ETH Zürich, HCI H 439 Vladimir-Prelog-Weg 1-5/10 8093 Zürich SWITZERLAND
Telephone	+393351003074
E-mail	dario.neri@pharma.ethz.ch
Department	Chemistry and Applied Biosciences
Relationship	Lecturer

Number	Title	ECTS	Hours	Lecturers
535-0002-00L	Introduction to Pharmaceutical Sciences II	3 credits	2V	J. Hall, K.‑H. Altmann, S. M. Ametamey, S.‑D. Krämer, J.‑C. Leroux, D. Neri, U. Quitterer, R. Schibli, C. Steuer
Abstract	First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities.
Learning objective	First identification with Pharmaceutical Sciences; motivation for profiling in the Natural Sciences, which are focused on within the first two years as a preparation for the specialized studies; sensitization for the duties and the responsibilities of a person with a federal diploma in Pharmacy; information about job opportunities.
Content	Introduction to Pharmaceutical Sciences by selected milestones of research and development. Overview on research activities at the Institute of Pharmaceutical Sciences, which is focused on drug delivery and development (from concepts to prototypes). Sensitization for communication skills and information management. Demonstration of job opportunities in community pharmacies, in the hospital, in industry, and in the public sector by experts in the different fields.
Lecture notes	Handouts for individual lectures.
Prerequisites / Notice	Interactive teaching
535-0900-00L	Seminars on Drug Discovery and Development	1 credit	1K	R. Schibli, K.‑H. Altmann, M. Detmar, C. Halin Winter, J. Hall, J.‑C. Leroux, D. Neri, U. Quitterer, G. Schneider, H. U. Zeilhofer
Abstract	State-of-the-art information on drug discovery and development by experts from academia and industry.
Learning objective	State-of-the-art information on drug discovery and development.
Content	Seminar series of the Institute of Pharmaceutical Sciences. Experts from academia and industry report on relevant topics.
535-0901-00L	From A to Z in Drug Discovery and Development Does not take place this semester.	2 credits	2S	J. Hall, K.‑H. Altmann, M. Detmar, D. Neri, R. Schibli, H. U. Zeilhofer
Abstract	The lecture series takes place at the ETH Hönggerberg and covers a variety of major activities involved in drug discovery: selecting drug targets, technologies used in drug discovery, small, medium and large drugs, objectives of the medicinal chemist, assessing drug safety, principles of personalized medicine, designing clinical trials, how intellectual property is protected, as well as others.
Learning objective	The objective of the course is to gain a global understanding of most of the important phases in the discovery and development of modern synthetic and biological drugs, from the first activities to clinical trials. The lecture is intended for students that have an interest in the area and/or may consider a career working in drug discovery. This lecture course complements knowledge and experience gained in the research project performed by the PhD student.
Content	Fifteen two hour lectures for life-science PhD students, given by experts from the ETH, UZH, USZ and the pharmaceutical industry. Introduction to the modern drug discovery process - Principles of drug pharmacokinetics and drug metabolism - Computer sciences in drug discovery - Drug targets - In vitro methods in drug discovery - Natural products in drug discovery - Medicinal chemistry: Chemical lead selection/optimization - Nucleic acid-based drugs - Antibodies and therapeutic proteins: Targets and drugs - In vivo molecular imaging in drug discovery - Personalized medicine in drug discovery and development - Drug formulation: Key development consideration, Current new APIs challenges and FDA rising standards - Preclinical safety, adverse drug events and drug-drug interactions - Clinical development steps including trial design - Intellectual property in drug discovery and development
Lecture notes	Scripts to be uploaded into ILIAS
Literature	To be distributed during the lecture
Prerequisites / Notice	Formally none, but a basic understanding in biochemistry, physiology and chemistry is highly desirable as it will certainly help to get the most from the lectures.