Martin Badertscher: Catalogue data in Autumn Semester 2020

Name Dr. Martin Badertscher
DepartmentChemistry and Applied Biosciences
RelationshipLecturer

NumberTitleECTSHoursLecturers
529-0041-00LModern Mass Spectrometry, Hyphenated Methods, and Chemometrics6 credits3GR. Zenobi, M. Badertscher, D. Günther, B. Hattendorf, P. Sinués Martinez-Lozano
AbstractModern mass spectrometry, hyphenated analytical methods, speciation, methods of surface analysis, chemometrics.
ObjectiveComprehensive knowledge about the analytical methods introduced in this course, and their applications.
ContentCoupling of separation with identification methods such as GC-MS, LC-MS, GC-IR, LC-IR, LC-NMR etc.; importance of speciation.
Modern mass spectrometry: Time of flight and ion cyclotron resonance mass spectrometry, ICP-MS. Soft ionization methods, desorption methods, spray methods.
Methods of surface analysis (ESCA, Auger, SIMS, raster microscopy methods).
Employment of computer science for processing data in chemical analysis (chemometrics).
Lecture noteslecture notes will be available in the lecture at production cost.
Literatureinformation about relevant literature will be available in the lecture & in the lecture notes.
Prerequisites / NoticeExercises are an integral part of the lecture.
Prerequisites:
529-0051-00 "Analytische Chemie I (3. Semester)"
529-0058-00 "Analytische Chemie II (4. Semester)"
(or equivalent)
529-0043-01LAnalytical Strategy Information 6 credits3GR. Zenobi, M. Badertscher, K. Eyer, S. Giannoukos, D. Günther
AbstractProblem-oriented development of analytical strategies and solutions.
ObjectiveAbility to create solutions for particular analytical problems.
ContentIndividual development of strategies for the optimal application of chemical, biochemical, and physico-chemical methods in analytical chemistry solving predefined problems. Experts from industry and administration present particular problems in their field of activity.
Principles of sampling.
Design and application of microanalytical systems.
Lecture notesCopies of problem sets and solutions will be distributed free fo charge
Prerequisites / NoticePrerequisites:
529-0051-00 "Analytical Chemistry I (3. Semester)"
529-0058-00 "Analytical Chemistry II (4. Semester)"
(or equivalent)
529-0073-00LRadiochemistry Information 2 credits2VM. Badertscher
AbstractPrinciples and phenomena around radioactivity.
ObjectiveKnowledge of the most important phenomena in relation with radioactivity. Knowledge of the principles of radiation protection. Ability to judge dangerous situations in handling radioactive materials, geopolitically as well as locally at ones own working place.
ContentStructure and properties of atomic nuclei, mathematical description of the radioactive decay, decay types, interaction of radiation with matter, detectors for ionizing radiation, radiation protection, principles of isotope separation, nuclear power plants, major nuclear accidents.

Additional topics may be suggested by the students.

Stress is on chemical aspects of radioactivity and on radiation protection.
Lecture notesA script is available free of charge.
LiteratureJ.-P. Adloff, R. Guillaumont, Fundamentals of Radiochemistry, CRC Press, London 1993

G. R. Choppin, J. Rydberg, J. O. Liljenzin, Radiochemistry and Nuclear Chemistry, Butterworth-Heinemann Ltd, Oxford 1995

K. H. Lieser, Einführung in die Kernchemie, Verlag Chemie, 2. Auflage, Weinheim 1980

Weitere Literaturangaben werden nach Bedarf in der Vorlesung abgegeben.
529-1042-00LAnalytics Information 2 credits1.5GM. Badertscher
AbstractPrinciples of the most important separation techniques and the interpretation of molecular spectra.
ObjectiveKnowledge of the necessary basics and the possibilities of application of the relevant spectroscopical and separation methods in analytical chermistry.
ContentApplication oriented basics of instrumental analysis in organic chemistry and the empirical employment of the methods of structure elucidation (mass spectrometry, NMR-, IR-, UV/VIS spectroscopy). Basics and application of chromatographic and electrophoretic separation methods. Application of the knowledge by practising.
Lecture notesA comprehensive script is available in the HCI-Shop. A summary of the part "Spektroskopie" defines the relevant material for the exam.
Literature- Pretsch E., Bühlmann P., Badertscher M. Structure Determination of Organic Compounds, 5th revised and enlarged English edition, Springer-Verlag, Berlin 2009;
- Pretsch E., Bühlmann P., Badertscher M., Spektroskopische Daten zur Strukturaufklärung organischer Verbindungen, fünfte Auflage, Springer-Verlag, Berlin 2010;
- D.A. Skoog, J.J. Leary, Instrumentelle Analytik, Grundlagen, Geräte, Anwendungen, Springer, Berlin, 1996;
- K. Cammann, Instrumentelle Analytische Chemie, Verfahren, Anwendungen, Qualitätssicherung, Spektrum Akademischer Verlag, Heidelberg, 2001;
- R. Kellner, J.-M. Mermet, M. Otto, H.M. Widmer, Analytical Chemistry, Wiley-VCH Verlag, Weinheim, 1998;
- K. Robards, P.R.Haddad, P.E. Jackson, Principles and practice of modern chromatographic methods, Academic Press, London, 1994;
Prerequisites / NoticePrerequisites:
- 529-1001-01 V "Allgemeine Chemie I (für Biol./Pharm.Wiss.)"
- 535-1001-00 P "Allgemeine Chemie I (für Biol./Pharm.Wiss.)"
- 529-1011-00 G "Organische Chemie I (für Biol./Pharm.Wiss.)"
551-1003-00LMethods of Biological Analysis Information 3 credits3GM. Badertscher, P. Picotti, K. Weis
Abstract529-1042-00
Principles of the most important separation techniques and the interpretation of molecular spectra.

551-1003-00
The course will teach the basis and typical applications of methods for the analysis of nucleic acid sequences, mass spectrometric analysis of proteins and proteomes and advanced light and fluorescent imaging methods.
Objective529-1042-00
Knowledge of the necessary basics and the possibilities of application of the relevant spectroscopical and separation methods in analytical chermistry.

551-1003-00
Knowledge of the theoretical basis of the methods for nucleic acid sequence analysis, mass spectrometry based protein and proteome analysis and advanced light and fluorescent imaging methods, and an understanding of the application of these principles in experimental biology.
Content529-1042-00
Application oriented basics of instrumental analysis in organic chemistry and the empirical employment of the methods of structure elucidation (mass spectrometry, NMR-, IR-, UV/VIS spectroscopy). Basics and application of chromatographic and electrophoretic separation methods. Application of the knowledge by practising.

551-1003-00
The course will consist of lectures covering the theoretical and technical base of the respective analytical methods and of exercises where typical applications of the methods in modern experimental biology are discussed.
Lecture notes529-1042-00
A comprehensive script is available in the HCI-Shop. A summary of the part "Spektroskopie" defines the relevant material for the exam.

551-1003-00
Materials supporting the lectures and exercises will be made available via Moodle.
Literature529-1042-00
- Pretsch E., Bühlmann P., Badertscher M. Structure Determination of Organic Compounds, 5th revised and enlarged English edition, Springer-Verlag, Berlin 2009;
- Pretsch E., Bühlmann P., Badertscher M., Spektroskopische Daten zur Strukturaufklärung organischer Verbindungen, fünfte Auflage, Springer-Verlag, Berlin 2010;
- D.A. Skoog, J.J. Leary, Instrumentelle Analytik, Grundlagen, Geräte, Anwendungen, Springer, Berlin, 1996;
- K. Cammann, Instrumentelle Analytische Chemie, Verfahren, Anwendungen, Qualitätssicherung, Spektrum Akademischer Verlag, Heidelberg, 2001;
- R. Kellner, J.-M. Mermet, M. Otto, H.M. Widmer, Analytical Chemistry, Wiley-VCH Verlag, Weinheim, 1998;
- K. Robards, P.R.Haddad, P.E. Jackson, Principles and practice of modern chromatographic methods, Academic Press, London, 1994;
Prerequisites / Notice529-1042-00
Prerequisites:
- 529-1001-01 V "Allgemeine Chemie I (für Biol./Pharm.Wiss.)"
- 529-1001-00 P "Allgemeine Chemie I (für Biol./Pharm.Wiss.)"
- 529-1011-00 G "Organische Chemie I (für Biol./Pharm.Wiss.)"