Martin Badertscher: Catalogue data in Autumn Semester 2018 |
| Name | Dr. Martin Badertscher |
| Department | Chemistry and Applied Biosciences |
| Relationship | Lecturer |
| Number | Title | ECTS | Hours | Lecturers | |
|---|---|---|---|---|---|
| 529-0041-00L | Modern Mass Spectrometry, Hyphenated Methods, and Chemometrics | 6 credits | 3G | R. Zenobi, M. Badertscher, B. Hattendorf | |
| Abstract | Modern mass spectrometry, hyphenated analytical methods, speciation, methods of surface analysis, chemometrics. | ||||
| Learning objective | Comprehensive knowledge about the analytical methods introduced in this course, and their applications. | ||||
| Content | Coupling of separation with identification methods such as GC-MS, LC-MS, GC-IR, LC-IR, LC-NMR etc.; importance of speciation. Modern mass spectrometry: Time of flight and ion cyclotron resonance mass spectrometry, ICP-MS. Soft ionization methods, desorption methods, spray methods. Methods of surface analysis (ESCA, Auger, SIMS, raster microscopy methods). Employment of computer science for processing data in chemical analysis (chemometrics). | ||||
| Lecture notes | lecture notes will be available in the lecture at production cost. | ||||
| Literature | information about relevant literature will be available in the lecture & in the lecture notes. | ||||
| Prerequisites / Notice | Exercises are an integral part of the lecture. Prerequisites: 529-0051-00 "Analytische Chemie I (3. Semester)" 529-0058-00 "Analytische Chemie II (4. Semester)" (or equivalent) | ||||
| 529-0043-00L | Analytical Strategy  Only for Chemistry MSc, Programme Regulations 2005. | 7 credits | 3G | R. Zenobi, M. Badertscher, G. Goubert, A. G. Graham, D. Günther | |
| Abstract | Problem-oriented development of analytical strategies and solutions. | ||||
| Learning objective | Ability to create solutions for particular analytical problems. | ||||
| Content | Individual development of strategies for the optimal application of chemical, biochemical, and physico-chemical methods in analytical chemistry solving predefined problems. Experts from industry and administration present particular problems in their field of activity. Principles of sampling. Design and application of microanalytical systems. | ||||
| Lecture notes | Copies of problem sets and solutions will be distributed free fo charge | ||||
| Prerequisites / Notice | Prerequisites: 529-0051-00 "Analytical Chemistry I (3. Semester)" 529-0058-00 "Analytical Chemistry II (4. Semester)" (or equivalent) | ||||
| 529-0043-01L | Analytical Strategy | 6 credits | 3G | R. Zenobi, M. Badertscher, G. Goubert, A. G. Graham, D. Günther | |
| Abstract | Problem-oriented development of analytical strategies and solutions. | ||||
| Learning objective | Ability to create solutions for particular analytical problems. | ||||
| Content | Individual development of strategies for the optimal application of chemical, biochemical, and physico-chemical methods in analytical chemistry solving predefined problems. Experts from industry and administration present particular problems in their field of activity. Principles of sampling. Design and application of microanalytical systems. | ||||
| Lecture notes | Copies of problem sets and solutions will be distributed free fo charge | ||||
| Prerequisites / Notice | Prerequisites: 529-0051-00 "Analytical Chemistry I (3. Semester)" 529-0058-00 "Analytical Chemistry II (4. Semester)" (or equivalent) | ||||
| 529-0073-00L | Radiochemistry | 2 credits | 2V | M. Badertscher | |
| Abstract | Principles and phenomena around radioactivity. | ||||
| Learning objective | Knowledge of the most important phenomena in relation with radioactivity. Knowledge of the principles of radiation protection. Ability to judge dangerous situations in handling radioactive materials, geopolitically as well as locally at ones own working place. | ||||
| Content | Structure and properties of atomic nuclei, mathematical description of the radioactive decay, decay types, interaction of radiation with matter, detectors for ionizing radiation, radiation protection, principles of isotope separation, nuclear power plants, major nuclear accidents. Additional topics may be suggested by the students. Stress is on chemical aspects of radioactivity and on radiation protection. | ||||
| Lecture notes | A script is available free of charge. | ||||
| Literature | J.-P. Adloff, R. Guillaumont, Fundamentals of Radiochemistry, CRC Press, London 1993 G. R. Choppin, J. Rydberg, J. O. Liljenzin, Radiochemistry and Nuclear Chemistry, Butterworth-Heinemann Ltd, Oxford 1995 K. H. Lieser, Einführung in die Kernchemie, Verlag Chemie, 2. Auflage, Weinheim 1980 Weitere Literaturangaben werden nach Bedarf in der Vorlesung abgegeben. | ||||
| 529-0075-00L | Radiochemistry (Practical Training) | 4 credits | 4P | M. Badertscher | |
| Abstract | Handling open and closed radioactive sources. Aspects of radiation protection. Handling detectors for ionizing radiation. | ||||
| Learning objective | Knowledge of the most important phenomena in relation with radioactivity. Knowlegde of the principles of radiation protection. Ability to handle radioactive material. | ||||
| Content | Handling open and closed radioactive sources. Getting accustomed to a variety of instruments and detectors for various kinds of ionizing radiation. Acquisition of working techniques under consideration of radiation protection. | ||||
| Lecture notes | Comprehensive material is available online. | ||||
| 529-1042-00L | Analytics | 2 credits | 1.5G | M. Badertscher | |
| Abstract | Principles of the most important separation techniques and the interpretation of molecular spectra. | ||||
| Learning objective | Knowledge of the necessary basics and the possibilities of application of the relevant spectroscopical and separation methods in analytical chermistry. | ||||
| Content | Application oriented basics of instrumental analysis in organic chemistry and the empirical employment of the methods of structure elucidation (mass spectrometry, NMR-, IR-, UV/VIS spectroscopy). Basics and application of chromatographic and electrophoretic separation methods. Application of the knowledge by practising. | ||||
| Lecture notes | A comprehensive script is available in the HCI-Shop. A summary of the part "Spektroskopie" defines the relevant material for the exam. | ||||
| Literature | - Pretsch E., Bühlmann P., Badertscher M. Structure Determination of Organic Compounds, 5th revised and enlarged English edition, Springer-Verlag, Berlin 2009; - Pretsch E., Bühlmann P., Badertscher M., Spektroskopische Daten zur Strukturaufklärung organischer Verbindungen, fünfte Auflage, Springer-Verlag, Berlin 2010; - D.A. Skoog, J.J. Leary, Instrumentelle Analytik, Grundlagen, Geräte, Anwendungen, Springer, Berlin, 1996; - K. Cammann, Instrumentelle Analytische Chemie, Verfahren, Anwendungen, Qualitätssicherung, Spektrum Akademischer Verlag, Heidelberg, 2001; - R. Kellner, J.-M. Mermet, M. Otto, H.M. Widmer, Analytical Chemistry, Wiley-VCH Verlag, Weinheim, 1998; - K. Robards, P.R.Haddad, P.E. Jackson, Principles and practice of modern chromatographic methods, Academic Press, London, 1994; | ||||
| Prerequisites / Notice | Prerequisites: - 529-1001-01 V "Allgemeine Chemie I (für Biol./Pharm.Wiss.)" - 535-1001-00 P "Allgemeine Chemie I (für Biol./Pharm.Wiss.)" - 529-1011-00 G "Organische Chemie I (für Biol./Pharm.Wiss.)" | ||||
| 551-1003-00L | Methods of Biological Analysis | 3 credits | 3G | R. Aebersold, M. Badertscher, K. Weis | |
| Abstract | 529-1042-00 Principles of the most important separation techniques and the interpretation of molecular spectra. 551-1003-00 The course will teach the basis and typical applications of methods for the analysis of nucleic acid sequences, mass spectrometric analysis of proteins and proteomes and advanced light and fluorescent imaging methods. | ||||
| Learning objective | 529-1042-00 Knowledge of the necessary basics and the possibilities of application of the relevant spectroscopical and separation methods in analytical chermistry. 551-1003-00 Knowledge of the theoretical basis of the methods for nucleic acid sequence analysis, mass spectrometry based protein and proteome analysis and advanced light and fluorescent imaging methods, and an understanding of the application of these principles in experimental biology. | ||||
| Content | 529-1042-00 Application oriented basics of instrumental analysis in organic chemistry and the empirical employment of the methods of structure elucidation (mass spectrometry, NMR-, IR-, UV/VIS spectroscopy). Basics and application of chromatographic and electrophoretic separation methods. Application of the knowledge by practising. 551-1003-00 The course will consist of lectures covering the theoretical and technical base of the respective analytical methods and of exercises where typical applications of the methods in modern experimental biology are discussed. | ||||
| Lecture notes | 529-1042-00 A comprehensive script is available in the HCI-Shop. A summary of the part "Spektroskopie" defines the relevant material for the exam. 551-1003-00 Materials supporting the lectures and exercises will be made available via Moodle. | ||||
| Literature | 529-1042-00 - Pretsch E., Bühlmann P., Badertscher M. Structure Determination of Organic Compounds, 5th revised and enlarged English edition, Springer-Verlag, Berlin 2009; - Pretsch E., Bühlmann P., Badertscher M., Spektroskopische Daten zur Strukturaufklärung organischer Verbindungen, fünfte Auflage, Springer-Verlag, Berlin 2010; - D.A. Skoog, J.J. Leary, Instrumentelle Analytik, Grundlagen, Geräte, Anwendungen, Springer, Berlin, 1996; - K. Cammann, Instrumentelle Analytische Chemie, Verfahren, Anwendungen, Qualitätssicherung, Spektrum Akademischer Verlag, Heidelberg, 2001; - R. Kellner, J.-M. Mermet, M. Otto, H.M. Widmer, Analytical Chemistry, Wiley-VCH Verlag, Weinheim, 1998; - K. Robards, P.R.Haddad, P.E. Jackson, Principles and practice of modern chromatographic methods, Academic Press, London, 1994; | ||||
| Prerequisites / Notice | 529-1042-00 Prerequisites: - 529-1001-01 V "Allgemeine Chemie I (für Biol./Pharm.Wiss.)" - 529-1001-00 P "Allgemeine Chemie I (für Biol./Pharm.Wiss.)" - 529-1011-00 G "Organische Chemie I (für Biol./Pharm.Wiss.)" | ||||